White Sox vs Giants Prediction 6/28/25 MLB Picks Today

The San Francisco Giants and Chicago White Sox meet Saturday in MLB action at Rate Field. Here’s a White Sox vs Giants Prediction. This article will include a White Sox vs Giants Pick.

San Francisco Giants Betting Preview

The San Francisco Giants are 45-37 on the year and play the Diamondbacks, Athletics, and Phillies next. The San Francisco Giants are batting .232 on the season, have a .313 OBP, and a .375 slugging percentage. The San Francisco Giants’ pitching staff has a 3.38 ERA and a 1.24 WHIP. Heliot Ramos leads the San Francisco Giants with 87 hits and 44 RBI, while Jung Hoo Lee and Wilmer Flores have combined for 142 hits and 89 RBI.

Robbie Ray gets the ball for the San Francisco Giants, and he is 8-2 with a 2.83 ERA and 104 strikeouts this season. Ray is 1-1 with a 3.08 ERA and 40 strikeouts in his career against the Chicago White Sox.

Chicago White Sox Betting Preview

The Chicago White Sox are 26-56 on the year and play the Dodgers, Rockies, and Blue Jays next. The Chicago White Sox are batting .220 on the season, have a .293 OBP, and a .343 slugging percentage. The Chicago White Sox pitching staff has a 4.18 ERA and a 1.40 WHIP. Miguel Vargas leads the Chicago White Sox with 68 hits and 34 RBI, while Lenyn Sosa and Chase Meidroth have combined for 121 hits and 31 RBI.

Adrian Houser gets the ball for the Chicago White Sox, and he is 2-2 with a 2.27 ERA and 26 strikeouts this season. Houser is 1-0 with a 3.38 ERA and 8 strikeouts in his career against the San Francisco Giants.

Why the Chicago White Sox will win

• The Giants have lost each of their last four games as favorites against AL Central opponents following a win.
• The White Sox have won three of their last four games as underdogs following a loss.
• The Giants have failed to cover the run line in each of their last 10 Saturday games as road favorites.
• The White Sox have covered the run line in seven of their last eight day games following a home loss.
• The Giants have trailed after 5 innings in each of their last four day games against AL Central opponents.
• The Giants have lost the first inning in each of their last three road games.
• The Giants have trailed after 3 innings in four of their last five day games against AL Central opponents that held a losing record.

Why the San Francisco Giants will win

• The White Sox have lost seven of their last eight games at Rate Field.
• The road team has won each of the Giants’ last four games.
• The road team has covered the run line in 10 of the Giants’ last 11 games.
• The White Sox have failed to cover the run line in each of their last seven Saturday games against National League opponents.
• The Giants have led after 3 innings in three of their last four games against American League opponents.
• The Giants have led after 5 innings in three of their last four day games against American League opponents that held a losing record.

Chicago White Sox Player Prop Facts

• Adrian Houser has recorded a win in each of his three previous appearances at Rate Field.
• Adrian Houser has recorded six strikeouts in three of his last four appearances in day games.
• Andrew Benintendi has hit a home run in three of the White Sox’s last four day games against NL opponents that held a winning record.
• Josh Rojas has recorded at least one hit in each of his last nine appearances with his team as an underdog against the Giants.

San Francisco Giants Player Prop Facts

• Heliot Ramos has hit a home run in three of his last five road appearances against AL Central opponents.
• Rafael Devers has recorded at least one hit in 17 of his last 18 road appearances against AL opponents.
• Tom Murphy has recorded a Double in four of his last five road appearances against AL Central opponents.
• Robbie Ray ranks T4th in the league for Wins (8) this season.

White Sox vs Giants Prediction

I’m going to continue fading the White Sox, as they just can’t get out of their own way. Houser has been solid this season with a 2.27 ERA and 1.26 WHIP, but it doesn’t matter when the White Sox have scored one or fewer runs in four of their last six games. Ray looks like an all-star again with his 2.83 ERA and 1.16 WHIP, and he’s allowing a .187 batting average in 36.1 road innings. Solid pitching matchup, but the Giants have the clear edge in offensive production. Give me the Giants and the somewhat reasonable price.