White Sox vs Giants Prediction 6/29/25 MLB Picks Today

In this article we will formulate a White Sox vs Giants prediction for this MLB game on Sunday, June 29th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 27-56 this year after they split the first two games in this series by scores of 1-3 and 1-0. In their game two win, Chicago scored the only run in the game in the sixth inning to sneak away with the win. The White Sox recorded seven hits in the game and they were led by Benintendi, who went 1-4 with one home run and one RBI in the win. Chicago started Houser, who allowed four hits and zero earned runs over 7.0 innings for the win, while Taylor picked up the save. 

Prior to this series, the White Sox lost two out of three against the Diamondbacks, but did win two out of three against the Blue Jays before that. Chicago has lost three of their last five games and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.12 ERA with a 1.39 WHIP and a .255 opponent batting average, while the offense has scored 282 runs with a .220 batting average and a .293 on base percentage this season. Miguel Vargas has led Chicago with 10 home runs and 34 RBIs, while Andrew Benintendi has added 10 home runs and 31 RBIs this year. The projected starting pitcher for Chicago is Jonathan Cannon, who is 2-7 with a 4.66 ERA and a 1.40 WHIP over 63.2 innings pitched this year. 

San Francisco Giants Betting Preview

The San Francisco Giants are 45-38 this season after they lost game two by a score of 1-0 on Saturday afternoon. San Francisco had very strong pitching in the game, but they couldn’t score any runs in the shutout loss. The Giants recorded four hits in the game and they were led by Koss, who went 2-4 in the loss. San Francisco started Ray, who allowed four hits and one earned run over 6.0 innings for the loss, while Miller and Rogers combined for two scoreless innings. 

Prior to this series, the Giants lost all three against the Marlins, but did win two out of three against the Red Sox before that. San Francisco has lost four of their last five games and they are currently third in the NL West standings. The San Francisco pitching staff has a 3.36 ERA with a 1.24 WHIP, and a .236 opponent batting average, while the offense has scored 347 runs with a .231 batting average and a .311 on base percentage this season. Wilmer Flores has led San Francisco with 11 home runs and 55 RBIs, while Heliot Ramos has added 13 home runs and 44 RBIs this year. The projected starting pitcher for San Francisco is Justin Verlander, who is 0-5 with a 4.52 ERA and a 1.41 WHIP over 61.2 innings pitched this season. 

Why the Giants will beat the White Sox

• The White Sox have lost each of their last nine games as home underdogs against National League opponents following a home win.
• The Giants have won each of their last six Sunday games against teams that held a losing record.
• The Giants have covered the run line in each of their last eight day games against American League opponents following a road loss.
• The White Sox have failed to cover the run line in each of their last five games following a win.
• The Giants have led after 3 innings in each of their last five Sunday games as favorites.

Total Runs Facts

• Each of the Giants’ last eight games against AL Central opponents have gone UNDER the total runs line.
• Four of the White Sox’s last five day games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Giants’ last four day games against AL Central opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the White Sox’s last seven games as home underdogs against NL West opponents.

Chicago White Sox Player Prop Facts

• Andrew Benintendi has hit a home run in four of the White Sox’s last five day games against NL opponents that held a winning record.
• Josh Rojas has recorded at least one hit in each of his last 10 appearances with his team as an underdog against the Giants.

San Francisco Giants Player Prop Facts

• Justin Verlander has recorded a win in four of his last five appearances against AL Central opponents that held a losing record.
• Justin Verlander has recorded six or more strikeouts in 23 of his last 27 road appearances against AL opponents that held a losing record.
• Matt Chapman has recorded at least one hit in each of his last seven appearances.
• Tom Murphy has hit a home run in two of his last three appearances against AL Central opponents.
• Tom Murphy has recorded a Double in four of his last five road appearances against AL Central opponents.
• Rafael Devers ranks 6th amongst qualified players for On Base Percentage (.392) this season.

Matchup/League Facts

• The White Sox rank 30th in the league for hits this season (597).
• The White Sox rank 30th in the league for RBIs this season (268).
• The Giants rank 2nd in the league for home runs allowed this season (65).
• The Giants rank 3rd in the league for walks this season (297).

White Sox vs Giants Prediction 

San Francisco comes into this matchup after dropping four of their last five games to Miami and Chicago, so they are really struggling right now. The Giants are 20-21 on the road this year, while the White Sox are 18-24 at home. Chicago has won two of their last three games and they are starting Cannon, who has allowed five earned runs in two straight starts, but hasn’t pitched since June 2nd. San Francisco will answer with Verlander, who has allowed three earned runs in three of his last five starts. I don’t love either starter in this game, but I do give the edge to San Francisco, especially with Cannon missing about a month. Take the Giants -1.5 here.