White Sox vs Guardians Prediction 8/10/25 MLB Picks Today

In this article we will formulate a White Sox vs Guardians prediction for this MLB game on Sunday, August 10th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 42-75 this season after they lost the first two games in this series by scores of 5-9 and 1-3. In their game two loss, Chicago tied the game at one in the second inning, but didn’t score over the final seven innings in the defeat. The White Sox recorded four hits in the game and they were led by Taylor, who went 2-3 with one home run and one RBI in the loss. Chicago started Burke, who allowed five hits and two earned runs over 3.1 innings for the loss, while Hudson allowed one earned run in relief. 

Prior to this series, the White Sox lost all three against the Mariners, but did win two out of three against the Angels before that. Chicago has lost six games in a row and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.16 ERA with a 1.37 WHIP and a .248 opponent batting average, while the offense has scored 446 runs with a .228 batting average and a .300 on base percentage this season. Miguel Vargas has led Chicago with 13 home runs and 44 RBIs, while Andrew Benintendi has added 14 home runs and 44 RBIs this year. The projected starting pitcher for Chicago is Davis Martin, who is 3-9 with a 4.11 ERA and a 1.29 WHIP over 96.1 innings pitched this season. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 61-55 this year after they won game two by a score of 3-1 on Saturday night. Cleveland jumped out to a 1-0 lead in the first inning, but they needed a run in the fourth to retake the lead and they added an insurance run in the sixth. The Guardians recorded seven hits and they committed one error in the game, while they were led by Manzardo, Kayfus, and Rocchio, who all had one RBI in the win. Cleveland started Cantillo, who allowed four hits and one earned run over 5.2 innings for the win, while Smith picked up the save. 

Prior to this series, the Guardians won all three games against the Mets and two out of three against the Twins. Cleveland has won nine of their last ten games and they are currently second in the AL Central standings. The Cleveland pitching staff has a 3.80 ERA with a 1.29 WHIP and a .239 opponent batting average, while the offense has scored 462 runs with a .229 batting average and a .302 on base percentage this season. Jose Ramirez has led Cleveland with 23 home runs and 61 RBIs, while Kyle Manzardo has added 18 home runs and 50 RBIs this year. The projected starting pitcher for Cleveland is Slade Cecconi, who is 5-4 with a 3.72 ERA and a 1.19 WHIP over 82.1 innings pitched this year. 

Why the Guardians will beat the White Sox

• The Guardians have won 12 of their last 13 games against the White Sox.
• The White Sox have lost each of their last six games.
• The road team has covered the run line in each of the Guardians’ last eight games.
• The White Sox have failed to cover the run line in five of their last six games.
• The Guardians have won the first inning in three of their last four road games against American League opponents that held a losing record.
• The White Sox have trailed after 3 innings in three of their last four games against American League opponents that held a winning record.
• The White Sox have trailed after 5 innings in each of their last seven games against American League opponents that held a winning record.

Total Runs Facts

• Four of the Guardians’ last five road games after playing the previous day have gone UNDER the total runs line.
• Three of the White Sox’s last four day games after playing the previous day have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Guardians’ last eight Sunday games at Rate Field.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the last 12 day games between the Guardians and White Sox at Rate Field.

Chicago White Sox Player Prop Facts

• Michael A. Taylor has hit a home run in three of the White Sox’s last four games as underdogs.
• Michael A. Taylor has recorded at least one hit in each of his last six appearances in day games against teams that held a winning record.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit a home run in each of the Guardians’ last two day games against opponents that held a losing record.
• Will Brennan has recorded at least one Double in each of his last three appearances with the Guardians as favorites against AL opponents.
• Lane Thomas has recorded at least one hit in each of his 12 previous road appearances against AL Central opponents that held a losing record.

White Sox vs Guardians Prediction 

Cleveland picked up yet another win on Saturday in game two of this series and they are going for the sweep here. The Guardians are 32-28 on the road this season, while the White Sox are 24-34 at home. Chicago has lost six games in a row and they are starting Martin, who has allowed at least three earned runs in three of his last four starts. Cleveland is going with Cecconi, who has allowed 2, 3, 2, 6, and 2 earned runs in his last five starts. These two teams are trending in opposite directions and Cleveland has all of the momentum, so take the Guardians here.