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White Sox vs Marlins Prediction 5/11/25 MLB Picks Today

Miami Marlins (15-23) vs. Chicago White Sox (11-29)
May 11, 2025 2:10 pm EDT
The Line: Chicago White Sox 114 / Miami Marlins -135; Over/Under: 8.5
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In this article, we will formulate a White Sox vs Marlins prediction for this MLB game on Sunday, May 11th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 11-29 this year, and they have split the first two games in the series by scores of 6-2 and 1-3. In their game two loss, Chicago led 1-0 in the first inning, but didn’t score in the final eight innings for the low-scoring loss. The White Sox recorded four hits in the game, and they were led by Vaughn, who went 1-4 with one home run and one RBI in the loss. Chicago started Smith, who allowed four hits and zero earned runs over 6.0 innings, while Wilson, Leasure, and Eisert allowed one earned run each in relief. 


Prior to this series, the White Sox lost all four games against the Royals, but did win two out of three against the Astros before that. Chicago has lost five of their last six games, and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.15 ERA with a 1.39 WHIP and a .247 opponent batting average, while the offense has scored 135 runs with a .214 batting average and a .291 on-base percentage this season. Luis Robert has led Chicago with five home runs and 16 RBIs, while Andrew Vaughn has added five home runs and 16 RBIs this year. The projected starting pitcher for Chicago is Sean Burke, who is 2-4 with a 4.35 ERA and a 1.32 WHIP over 39.1 innings pitched this year. 

Miami Marlins Betting Preview

The Miami Marlins are 15-23 this season after they won game two by a score of 3-1 on Saturday. Miami trailed for most of the game, but they scored once in the seventh and twice in the eighth to steal the win. The Marlins recorded seven hits in the game, and they were led by Wagaman, who went 1-4 with two RBIs in the win. Miami started Cabrera, who allowed three hits and one earned run over 5.0 innings, while Faucher picked up the win out of the bullpen. 

Prior to this series, the Marlins lost two out of three against the Dodgers and two out of three against the Athletics. Miami has lost 10 of its last 13 games, and they are currently last in the NL East standings. The Miami pitching staff has a 5.73 ERA with a 1.54 WHIP and a .269 opponent batting average, while the offense has scored 162 runs with a .247 batting average and a .311 on-base percentage this season. Matt Mervis has led Miami with seven home runs and 14 RBIs, while Kyle Stowers has added seven home runs and 26 RBIs this year. The projected starting pitcher for Miami is Sandy Alcantara, who is 2-4 with an 8.42 ERA and a 1.61 WHIP over 31.0 innings pitched this season. 

Why the White Sox will beat the Marlins

  • The underdogs have won each of the Marlins’ last four games at Rate Field.
  • The Marlins have lost four of their last five games as road favorites against AL Central opponents.
  • The underdogs have covered the run line in each of the Marlins’ last six games at Rate Field.
  • The Marlins have failed to cover the run line in 19 of their last 22 games as favorites.
  • The Marlins have trailed after 3 innings in each of their last 11 road games.
  • The Marlins have trailed after 5 innings in each of their last seven road games.

Total Runs Facts

  • Ten of the Marlins’ last 11 road games have gone OVER the total runs line.
  • Seven of the White Sox’s last eight home games against NL East opponents have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the Marlins’ last 10 road games against American League opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the White Sox’s last nine home games.

Chicago White Sox Player Prop Facts

  • Andrew Benintendi has hit at least one home run in three of his last four appearances at Rate Field against NL opponents that held a losing record.
  • Andrew Vaughn has recorded at least one hit in each of the White Sox’s last 10 Sunday games.
  • Andrew Vaughn has recorded an RBI in each of the White Sox’s last four games against NL East opponents that held a losing record.
  • Korey Lee has recorded a Single in each of his last five appearances with the White Sox as underdogs against NL East opponents.
  • Andrew Benintendi has scored a run in each of his last five appearances.

Miami Marlins Player Prop Facts

  • Sandy Alcantara has recorded five or more strikeouts in 13 of his last 15 appearances against AL opponents.
  • Jesus Sanchez has hit a home run in six of his last 29 appearances with the Marlins against AL opponents.
  • Otto Lopez has recorded at least one hit in each of his last eight appearances against AL opponents that held a losing record.
  • Sandy Alcantara has recorded a win in three of his last four appearances with the Marlins as favorites.
  • Jesus Sanchez has recorded an RBI in three of the Marlins’ last four games.
  • Otto Lopez has recorded at least one Single in each of his last seven appearances against AL opponents that held a losing record.

White Sox vs Marlins Prediction 

These two teams have split the first two games of this series, and each side will be looking for a rare series win here. The Marlins are 5-11 on the road this year, while the White Sox are 8-12 at home. Chicago has scored one run or fewer in three of their last four games, but they will go against Alcantara, who has allowed 12 earned runs and 13 hits over his last 7.2 innings. Miami has scored a total of six runs in its last three games, and it will go against Burke, who has allowed one earned run or fewer in three of his last four starts. Both lineups are struggling to score runs, but I think the White Sox have the advantage on the mound. Take Chicago here. 

David Racey's Free Pick: White Sox ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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