White Sox vs Red Sox Prediction 4/18/25 MLB Picks Today

The Chicago White Sox are visiting the Boston Red Sox on Friday, April 18^th at the Fenway Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Chicago White Sox vs Boston Red Sox Prediction. We will examine:

The Boston Red Sox recent form and player performance

The Chicago White Sox recent form and player performance

Recent betting trends and streaks involving the Boston Red Sox

Recent betting trends and streaks involving the Chicago White Sox

Recent betting trends in games played between the Chicago White Sox vs Boston Red Sox

A summary that ties it all together and produces a favorable betting outcome for Chicago White Sox vs Boston Red Sox game

Boston Red Sox Preview

The Boston Red Sox have a 10-10 record this season and are sitting on the third place of the AL East. The Red Sox have a 4-3 home record and are 7-12 in over/under. They are coming off a 1-0 road victory over the Tampa Bay Rays and are playing the Mariners and the Guardians next. They are 3-1 in their last 4 games and 7-3 to the under in their last 10. The Red Sox have a .247 batting average this season, .320 OBP and .382 slugging percentage. Boston’s pitching staff has a 4.16 ERA and 1.33 WHIP.  Alex Bregman leads the Red Sox with 25 hits, 16 RBI, 4 home runs and a team-high .321 batting average.

Hunter Dobbins (R) will take the mound for the Red Sox, and he has a 1-0 record, 0.60 ERA and 0.73 WHIP. He has allowed just one earned run in his three starts this season in 15 innings of work, and he has been terrific in his three starts against the Yankees in his career, with zero earned runs in 18.2 innings of work.

Chicago White Sox Preview

The Chicago White Sox have a 4-14 record this season and are sitting on the last place of the AL Central. The White Sox have a 0-6 road record and are 7-8 in over/under. They are coming off a 0-8 road defeat by the Athletics, and have four consecutive losses. Under is 6-2-2 in their last 10 games and are playing the Twins and the Athletics next. The White Sox have a .196 batting average this season, .270 OBP and .296 Slugging percentage. Chicago’s pitching staff has a 4.26 ERA and 1.32 WHIP. Lenyn Sosa leads the White Sox with 16 hits and a team-high .281 batting average. Andrew Vaughn leads the team in RBI, with 8.

Martin Perez (L) will take the mound for the White Sox, and he has a 1-0 record, 1.59 ERA and 1.06 WHIP. In his previous start against the Red Sox this season, he gave up two runs in 4.2 innings of work.

Why the Boston Red Sox will win

• The White Sox have lost each of their last six road games.
• The Red Sox have won each of their last five night games against the White Sox at Fenway Park following a win.
• The White Sox have failed to cover the run line in eight of their last nine games as underdogs against AL East opponents following a home loss.
• The Red Sox have covered the run line in four of their last five night games against the White Sox at Fenway Park following a win.
• The Red Sox have led after 3 innings in six of their last seven games as home favorites against AL Central opponents.
• The Red Sox have led after 5 innings in seven of their last eight home games against AL Central opponents.

Why the Chicago White Sox will win

• The Red Sox have lost six of their last seven games as favorites against American League opponents following a win.
• The White Sox have won three of their last four games as underdogs against AL East opponents following a loss.
• The Red Sox have failed to cover the run line in seven of their last eight night games at Fenway Park following a road win.
• The road team has covered the run line in each of the White Sox’s last four games.
• The Red Sox have trailed after 5 innings in three of their last four night games against opponents that held a losing record.
• The Red Sox have trailed after 3 innings in three of their last four night games against opponents that held a losing record.

Total Runs Facts

• Ten of the Red Sox’s last 11 games as favorites against American League opponents have gone UNDER the total runs line.
• Five of the White Sox’s last six night games against AL East opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the Red Sox’s last 11 games as favorites against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the White Sox’s last nine games at Fenway Park.

Matchup/League Facts

• The Red Sox rank 30th in the league for strikeouts against this season (197).
• The Red Sox rank 29th in the league for hits allowed this season (177).
• The White Sox rank 30th in the league for hits this season (112).
• The White Sox rank 30th in the league for batting average this season (.196).

White Sox vs Red Sox Prediction

The White Sox won their previous series against the Red Sox this season by 2-1 wins in Chicago. They are 3-1 in their last 4 meetings against the Red Sox and under is 3-1 in their last 4 meetings.

In this White Sox vs Red Sox Prediction, the Red Sox are coming as big -205 home favorites. The Red Sox are rightfully favored, as they have been the better team this season, but they are putting an inexperienced pitcher on the mound, while the White Sox are putting one of their best. Chicago won in Perez’ previous start against Boston this season, and this line is simply too big to back the home favorite. I expect Perez to keep the Red Sox’s bats at bay once again and keep this one close in the first half, so take the White Sox at +0.5 runs in the first 5 innings.