
White Sox vs Tigers Prediction 6/4/25 MLB Picks Today
Detroit Tigers (40-22) vs. Chicago White Sox (19-42)
June 4, 2025 7:40 pm EDT
The Line: Chicago White Sox 160 / Detroit Tigers -192; Over/Under: 8.5
(Get latest betting odds)
In this article, we will formulate a White Sox vs Tigers prediction for this MLB game on Wednesday, June 4, at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup.
Detroit Tigers Betting Preview
The Detroit Tigers (40-22, 19-14 Away) rarely lose series this season, but even though they lost to the Cleveland Guardians, the Tigers responded with a sweep of the Giants and a win against the Royals. The current four-game series against the White Sox is tied at one apiece after Chicago’s 8-1 win last night. In a bullpen day for Detroit, Brant Hurter took the loss after allowing one run on one hit with four strikeouts and one walk in 2.0 innings.
This season, the Tigers average 5.07 runs per game (4th in the MLB) on a .251/.324/.413 triple-slash. When it comes to pitching, the Tigers’ staff has a 3.13 ERA (5th) and 1.15 WHIP (2nd). Spencer Torkelson leads the Tigers with a .236 batting average, 14 home runs, and 42 RBI this season.
Sawyer Gipson-Long will take the mound for the Tigers on Wednesday. The 27-year-old right-hander will pitch for the first time since 2023.
Chicago White Sox Betting Preview
The Chicago White Sox (19-42, 13-16 Home) returned home from two road series, during which they lost to the Mets and were swept by the Orioles. Following a massive 13-1 defeat in Game 1, the White Sox responded with an 8-1 win. Michael Taylor led the offense with four RBI, while Shane Smith got the win after allowing no runs on three hits with six strikeouts and two walks across 5.1 innings of work.
This year, the White Sox average 3.37 runs per game (27th in the MLB) on a .220/.292/.341 triple-slash. When it comes to pitching, the White Sox’s staff has a 4.25 ERA (23rd) and 1.38 WHIP (23rd). Miguel Vargas leads the White Sox with a .243 batting average, eight home runs, and 26 RBI this season.
The White Sox haven’t announced their starting pitcher at the time of writing.
Total Runs Facts
- Each of the White Sox’s last four home games have gone OVER the total runs line.
- Each of the Tigers’ last four night games against American League opponents have gone OVER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the White Sox’s last seven night games against AL Central opponents.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Tigers’ last six games at Rate Field.
Matchup/League Facts
- The White Sox rank 28th in the league for hits this season (440).
- The White Sox rank 28th in the league for home runs this season (48).
- The Tigers rank 27th in the league for strikeouts against this season (557).
- The Tigers are one of only four teams in the league to rank top 10 in both strikeouts and walks allowed this season.
White Sox vs Tigers Prediction
The Tigers won seven of the previous ten H2H encounters, including four of the last five. In one series this season, the Tigers swept the White Sox in three games in Detroit. Given the situation with starting pitchers for this game, I am going with Over. Gipson-Long hasn’t pitched for two years, and he will definitely be rusty in this one, while it’s likely going to be a bullpen day for the White Sox. Four of five H2H meetings this year went Over. Go with another high-scoring affair here.