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White Sox vs Tigers Prediction 8/13/25 MLB Picks Today

Detroit Tigers (69-52) vs. Chicago White Sox (44-76)
August 13, 2025 2:10 pm EDT
The Line: Chicago White Sox / Detroit Tigers; Over/Under:
(Get latest betting odds)

In this article we will formulate a White Sox vs Tigers prediction for this MLB game on Wednesday, August 13th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 44-76 this year after they split the first two games in this series by scores of 1-2 and 9-6. In their game two win, Chicago trailed 1-0 in the fourth, but they scored the next six runs to pull away with the win. The White Sox recorded 13 hits and they committed two errors in the game, while they were led by Quero, who went 3-5 with one home run and three RBIs in the win. Chicago started Gomez, who allowed one hit and one earned run over 5.0 innings for the win, while Leasure picked up the save. 

Prior to this series, the White Sox lost two out of three against the Guardians and all three against the Mariners. Chicago has lost seven of their last nine games and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.15 ERA with a 1.36 WHIP and a .248 opponent batting average, while the offense has scored 462 runs with a .229 batting average and a .301 on base percentage this season. Lenyn Sosa has led Chicago with 14 home runs and 48 RBIs, while Andrew Benintendi has added 14 home runs and 45 RBIs this year. The projected starting pitcher for Chicago is Shane Smith, who is 3-7 with a 4.22 ERA and a 1.29 WHIP over 96.0 innings pitched this year. 

Detroit Tigers Betting Preview

The Detroit Tigers are 69-52 this season after they lost game two in this series by a score of 9-6 on Tuesday. Detroit led 1-0 in the fourth inning, but their pitching staff had another awful game and they ended with the loss. The Tigers recorded eight hits and they committed one error in the game, while they were led by Keith, who went 2-5 with one home run and three RBIs in the loss. Detroit started Flaherty, who allowed eight hits and five earned runs over 4.1 innings for the loss, while Kahnle allowed two earned runs in relief. 

Prior to this series, the Tigers won two out of three against the Angels, but lost two out of three against the Twins before that. Detroit has won three of their last five games and they are still leading the AL Central standings. The Detroit pitching staff has a 3.87 ERA with a 1.24 WHIP and a .241 opponent batting average, while the offense has scored 583 runs with a .251 batting average and a .317 on base percentage this season. Riley Greene has led Detroit with 27 home runs and 87 RBIs, while Spencer Torkelson has added 26 home runs and 66 RBIs this year. The projected starting pitcher for Detroit is Keider Montero, who is 4-3 with a 4.66 ERA and a 1.43 WHIP over 73.1 innings pitched this season. 

Why the White Sox will beat the Tigers

  • The White Sox have won each of their last six Wednesday day games against the Tigers.
  • The Tigers have lost each of their last four day games against the White Sox at Rate Field following a road loss.
  • The White Sox have covered the run line each of their last nine day games against teams that held a winning record.
  • The Tigers have failed to cover the run line each of their last six road games against teams that held a losing record.
  • The Tigers have trailed after 5 innings in four of their last five road games against opponents that held a losing record.
  • The White Sox have led after 3 innings in each of their last three day games against AL Central opponents that held a winning record.

Why the Tigers will beat the White Sox

  • The Tigers have won each of their last nine games against AL Central opponents following a road loss.
  • The White Sox have lost each of their last eight Wednesday games against AL Central opponents.
  • The Tigers have covered the run line in eight of their last nine day games against American League opponents following a road loss.
  • The White Sox have failed to cover the run line in each of their last five day games against American League opponents following a win.
  • The Tigers have led after 3 innings in each of their last five day games.
  • The Tigers have led after 5 innings in four of their last five day games.

Total Runs Facts

  • Each of the Tigers’ last seven day games against American League opponents have gone OVER the total runs line.
  • Four of the White Sox’s last five day games after playing the previous day have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Tigers’ last seven road games against American League opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the last five games between the Tigers and White Sox.

Chicago White Sox Player Prop Facts

  • Miguel Vargas has recorded at least one hit in each of his last five appearances in day games against AL teams that held a winning record.
  • Miguel Vargas has hit a home run in two of his last three appearances in day games.

Detroit Tigers Player Prop Facts

  • Riley Greene has recorded at least one Double in three of the Tigers’ last four games at Rate Field against opponents that held a losing record.
  • Kerry Carpenter has hit a home run in each of his last four appearances in day games against teams that held a losing record.
  • Wenceel Perez has recorded at least one hit in each of his nine previous appearances in day games against AL Central teams that held a losing record.

White Sox vs Tigers Prediction 

Chicago was able to pick up a nice win on Tuesday in game two of this series and they will look for a rare series win here. The White Sox are 26-35 at home this year, while the Tigers are 30-28 on the road. Detroit continues their slide and they are starting Montero, who has allowed 12 earned runs in his last three outings. Chicago is starting Smith, who has allowed two earned runs in three straight starts, but doesn’t go very deep into games. I don’t like the pitching matchup here, so I will take the over. 

David Racey's Free Pick: Over

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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