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White Sox vs Yankees Prediction 7/29/26 MLB Picks Today

NY Yankees (61-46) vs. Chicago White Sox (55-51)
July 29, 2026 7:40 pm EDT
The Line: Chicago White Sox 123 / NY Yankees -149; Over/Under: 7.5
(Get latest betting odds)

In this article we will formulate a White Sox vs Yankees prediction for this MLB game on Wednesday, July 29th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 55-51 this year after they lost the first two games in this series by scores of 5-9 and 2-3. In game two, Chicago trailed for most of the game, but they scored in the ninth to avoid the shutout. The White Sox recorded seven hits in the game and they were led by Meidroth, who went 1-4 with one home run and two RBIs. Kay allowed five hits and three earned runs over 5.1 innings for the loss, while Schweitzer threw three innings in relief. Prior to this series, Chicago lost two out of three against the Astros, but did win two out of three against the Rangers before that. 

This season, Chicago has a 4.14 ERA with a 1.31 WHIP and a .238 opponent batting average, while they have scored 508 runs with a .240 batting average and a .318 on base percentage. Colson Montgomery has led the White Sox with 24 home runs and 61 RBIs, while Miguel Vargas has added 22 home runs and 63 RBIs. The projected starting pitcher for Chicago is Davis Martin, who is 9-5 with a 3.49 ERA and a 1.27 WHIP over 111.0 innings pitched this year. 

New York Yankees Betting Preview

The New York Yankees are 61-46 this season after they won game two by a score of 3-2 on Tuesday night. New York scored three runs in the second inning, but failed to score over the last seven innings in the win. The Yankees recorded six hits in the game and they were led by Schuemann, who went 1-2 with two RBIs. Cole allowed four hits and zero earned runs over 6.0 innings for the win, while Bednar picked up the save. Prior to this series, New York won two out of three against the Phillies and two out of three against the Pirates. 

This season, New York has a 3.40 ERA with a 1.19 WHIP and a .227 opponent batting average, while they have scored 500 runs with a .234 batting average and a .313 on base percentage. Ben Rice has led the Yankees with 31 home runs and 73 RBIs, while Cody Bellinger has added 11 home runs and 53 RBIs. The projected starting pitcher for New York is Cam Schlittler, who is 10-6 with a 2.07 ERA and a 0.93 WHIP over 130.1 innings pitched this season. 

Why the Chicago White Sox will win

  • The Yankees have lost three of their last four games as favorites against American League opponents following a win.
  • The White Sox have won four of their last six games as home underdogs following a loss.
  • The White Sox have covered the run line in 11 of their last 12 games against teams that held a winning record.
  • The Yankees have failed to cover the run line in each of their last four games against American League opponents following a win.
  • The Yankees have lost the first inning in three of their last four games.
  • The Yankees have trailed after 3 innings in seven of their last nine games as favorites against AL Central opponents.

Why the New York Yankees will win

  • The White Sox have lost each of their last 11 home games against AL East opponents.
  • The Yankees have won each of their last nine road games against AL Central opponents following a win.
  • The White Sox have failed to cover the run line in nine of their last 10 home games against AL East opponents.
  • The Yankees have covered the run line in each of their last six Wednesday road games against AL Central opponents.
  • The White Sox have trailed after 3 innings in three of their last four games as underdogs.
  • The White Sox have trailed after 5 innings in seven of their last eight night games at Rate Field against AL East opponents.

Total Runs Facts

  • Six of the Yankees’ last seven games as road favorites have gone UNDER the total runs line.
  • Four of the White Sox’s last five night games as underdogs have gone OVER the total runs line.
  • There has been no run scored during the first inning in seven of the White Sox’s last eight games against AL East opponents.
  • There has been no run scored during the first inning in five of the Yankees’ last six games as road favorites against AL Central opponents.

Chicago White Sox Player Prop Facts

  • Chase Meidroth has hit a home run in two of the White Sox’s last three games.
  • Davis Martin has recorded six or more strikeouts in four of his last five appearances with the White Sox as home underdogs.
  • Miguel Vargas has recorded a hit in each of his eight previous home appearances against the Yankees.
  • Davis Martin has recorded a win in five of his last six home appearances against opponents that held a winning record.
  • Colson Montgomery ranks 10th in the league in Home Runs (24) this season.

New York Yankees Player Prop Facts

  • Austin Wells has hit a home run in each of his last two road appearances against the White Sox after playing the previous day.
  • Cam Schlittler has recorded eight or more strikeouts in four of his last five appearances in night games.
  • Amed Rosario has recorded at least one hit in each of his 11 previous appearances at Rate Field against opponents that held a winning record.
  • Ben Rice ranks 2nd amongst qualified players for Slugging Percentage (.585) this season.

Matchup/League Facts

  • The White Sox rank 24th in the league for hits this season (844).
  • The White Sox rank 24th in the league for hits this season (844).
  • The Yankees rank 1st in the league for ERA this season (3.41).
  • The Yankees rank 1st in the league for ERA this season (3.41).

White Sox vs Yankees Prediction 

New York picked up another win on Tuesday night in game two and they have allowed two runs or fewer in three of their last five games. The Yankees are 35-23 on the road this year, while the White Sox are 32-21 at home. Chicago has lost four of their last five games, but they still lead the AL Central by 1.5 games. The White Sox are starting Martin, who has allowed 4, 1, and 5 earned runs in his last three starts, while Schlittler has allowed two earned runs or fewer in three of his last four outings. Take the under here, as both pitchers have been very good all season. 

David Racey's Free Pick: Under 7.5

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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