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Yankees vs White Sox Prediction 8/28/25 MLB Picks Today

Yankees vs White Sox
August 28, 2025 7:40 pm EDT
The Line: White Sox +171 / Over/Under: 9
(Get latest betting odds)

In this article, we will formulate a Yankees vs White Sox Prediction for this MLB game on Thursday, August 28th at the Rate Field in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago White Sox Preview

The Chicago White Sox have a 48-85 record this season and are sitting on the last place of the AL Central. The White Sox have a 29-39 home record and are 61-64 in over/under. They are coming off a 1-12 home defeat by the Royals, and have back-to-back losses. Over is 4-2 in their last 6 games and are playing the Twins and the Tigers next.


The White Sox have a .234 batting average this season, .303 OBP and .374 Slugging percentage. Chicago’s pitching staff has a 4.20 ERA and 1.36 WHIP. Lenyn Sosa leads the White Sox with 113 hits, and he is the team’s best hitter with a .270 batting average. He also leads the team in RBI with 60, adding a team-high 17 home runs.

Davis Martin (R) is the projected starting pitcher for the White Sox, and he has a 5-9 record, 3.93 ERA and 1.26 WHIP.

New York Yankees Preview

The New York Yankees have a 73-60 record this season and are sitting on the third place of the AL East. The Yankees have a 32-32 road record and are 63-65 in over/under. They are coming off a 11-2 home victory over the Nationals, and have four consecutive wins. Over is 8-2 in their last 10 games and are playing the Astros and the Blue Jays next.

The Yankees have a .251 batting average this season, .331 OBP and .456 Slugging percentage. New York’s pitching staff has a 3.99 ERA and 1.26 WHIP. Aaron Judge leads the Yankees with 144 hits, adding team-highs both in RBI, with 95 and in home runs, with 41. He is also the team’s best hitter, with a .323 batting average.

Will Warren (R) is the projected starting pitcher for the Yankees, and he has a 7-6 record, 4.47 ERA and 1.40 WHIP.

Why the Chicago White Sox will win

  • The Yankees have lost each of their last four games as road favorites following a home win.
  • The White Sox have won three of their last four games as home underdogs following a home loss.
  • The Yankees have failed to cover the run line in 11 of their last 12 games as road favorites against American League opponents.
  • The White Sox have covered the run line in eight of their last nine home games after playing the previous day.
  • The Yankees have trailed after 3 innings in each of their last nine Thursday night games against opponents that held a losing record.
  • The White Sox have led after 5 innings in four of their last five games.

Why the New York Yankees will win

  • The Yankees have won each of their last seven games against teams that held a losing record.
  • The White Sox have lost each of their last nine Thursday night games against AL East opponents.
  • The Yankees have covered the run line each of their last seven games against teams that held a losing record.
  • The White Sox have failed to cover the run line in four of their last five home games against AL East opponents that held a winning record.
  • The Yankees have won the first inning in four of their last five road games.
  • The Yankees have led after 3 innings in each of their last seven games against American League opponents that held a losing record.
  • The Yankees have led after 5 innings in eight of their last nine night games against opponents that held a losing record.

Total Runs Facts

  • Each of the Yankees’ last four road games have gone OVER the total runs line.
  • Four of the White Sox’s last five home games against AL East opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the White Sox’s last six games as home underdogs against AL East opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Yankees’ last four games against American League opponents.

Matchup/League Facts

  • The White Sox rank 29th in the league for walks allowed this season (483).
  • The White Sox rank 28th in the league for slugging percentage this season (.374).
  • The Yankees rank 1st in the league for home runs this season (225).
  • The Yankees rank T1st in the league for RBIs this season (667).

Yankees vs White Sox Prediction

The Yankees are 5-1 in their last 6 head-to-head meetings against the White Sox, but both teams are tied 3-3 in their last 6 meetings in Chicago. Over is 3-1 in their last 4 meetings.

In this Yankees vs White Sox Prediction, the Yankees are coming as -190 home favorites. The White Sox might have the pitching advantage on paper, but this is a great price for a Yankees team against one of the weakest teams in baseball this season. The White Sox were destroyed yesterday by 1-12 by the Royals, while the Yankees annihilated the Nationals with a 3-0 series sweep with a combined 26-8 score. I expect them to roll over the White Sox and win by 2+ runs easily. Take the New York Yankees on the runline on the road.

Nikos Lagouretos's Free Pick: New York Yankees -1.5

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