Cavaliers vs 76ers
November 5, 2025 7:00 pm EDT
The Line: Cavaliers -10
(Get latest betting odds)
The Philadelphia 76ers and Cleveland Cavaliers meet Wednesday in NBA action at the Rocket Arena. Here’s a Cavaliers vs 76ers Prediction. This article will include a Cavaliers vs 76ers Pick.
Philadelphia 76ers Betting Preview
The Philadelphia 76ers beat the Nets, lost to the Bulls, and they play the Raptors next. The 76ers have won 5 of their last 7 games.
The Philadelphia 76ers are averaging 123.6 points on 47.1 percent shooting and allowing 117.6 points on 47 percent shooting. Tyrese Maxey is averaging 33.7 points and 9 assists, while VJ Edgecombe is averaging 20.3 points and 5 rebounds. Kelly Oubre Jr. is the third double-digit scorer and Quentin Grimes is grabbing 4.7 rebounds. The Philadelphia 76ers are shooting 40.2 percent from beyond the arc and 80.1 percent from the free-throw line. The Philadelphia 76ers are allowing 31.9 percent shooting from deep and are grabbing 42.6 rebounds per game.
Cleveland Cavaliers Betting Preview
The Cleveland Cavaliers lost to the Raptors, beat the Hawks, and they play the Wizards next. The Cavs have won 4 of their last 6 games.
The Cleveland Cavaliers are averaging 114.1 points on 44.5 percent shooting and allowing 114 points on 46.5 percent shooting. Donovan Mitchell is averaging 29.5 points and 4.5 assists, while Evan Mobley is averaging 19.3 points and 4.4 assists. De’Andre Hunter is the third double-digit scorer and Sam Merrill is grabbing 2 rebounds. The Cleveland Cavaliers are shooting 34.9 percent from beyond the arc and 75.5 percent from the free throw line. The Cleveland Cavaliers are allowing 37 percent shooting from deep and are grabbing 41.1 rebounds per game.
Why the Cleveland Cavaliers will win
- The 76ers have lost each of their last 12 road games against teams that held a winning record.
- The Cavaliers have won each of their last 10 games against opponents who are on the second leg of a back-to-back.
- The 76ers have failed to cover the spread in each of their last 12 games as road underdogs following a road loss.
- The Cavaliers have covered the spread in eight of their last nine games against Atlantic Division opponents that held a winning record.
Why the Philadelphia 76ers will win
- The 76ers have won each of their last five games against the Cavaliers following a road loss.
- The Cavaliers have lost three of their last four games as favorites against Atlantic Division opponents.
- The 76ers have covered the spread in each of their last nine games against the Cavaliers following a road loss.
- The Cavaliers have failed to cover the spread in 11 of their last 12 home games following a win.
Total Points Facts
- Eight of the last nine games between the 76ers and Cavaliers have gone OVER the total points line.
- Thirteen of the 76ers’ last 15 games as underdogs following a road loss have gone OVER the total points line.
Cleveland Cavaliers Player Facts
- Evan Mobley is one of only two qualified players in the league averaging at least 1.5 steals and 1.5 blocks this season.
- Donovan Mitchell is one of only two players in the league to have made 8+ threes in a game this season.
Philadelphia 76ers Player Facts
- Tyrese Maxey ranks 1st amongst qualified players for points per game (34.4) this season.
- Adem Bona ranks 2nd amongst qualified players for blocks per 36 minutes (4.0) this season.
Matchup/League Facts
- The Cavaliers rank 30th in the league for Q4 opponent points per game this season (31.3).
- The Cavaliers rank 1st in the league for Q3 win percentage this season (85.7%).
- The 76ers rank 1st in the league for blocks per game this season (7.6).
- The 76ers have recorded the largest comeback win from a Q3 deficit this season – trailed by 16 points @ Wizards on October 28.
Cavaliers vs 76ers Injury Report
The Cavs will be without Max Strus. Darius Garland, Jarrett Allen, and Sam Merrill are questionable.
The 76ers will be without Jared McCain, Paul George, and Dominick Barlow.
Cavaliers vs 76ers Prediction
The 76ers and the points are worth a look, but they’re on the end of a back-to-back, and this line tells me they’ll be without a lot of key players. It’s also not going to be easy to rebound from last night’s loss. It was rough. The Cavs are at home, rested, and they’re going to be as healthy as they’ve been in a while. There’s a chance Garland plays. Massive line, but oddsmakers are throwing this out there for a reason. I’ll lay the chalk.
