San Antonio Spurs (5-1) vs. LA Lakers (6-2)
November 5, 2025 10:00 pm EDT
The Line: LA Lakers -2.5; Over/Under: 230.5
(Get latest betting odds)
The San Antonio Spurs and the Los Angeles Lakers duke it out at the Crypto.com Arena on Wednesday night. Here’s a Lakers vs Spurs Prediction. This article will include a Lakers vs Spurs Pick.
San Antonio Spurs Betting Preview
The San Antonio Spurs were enjoying a five-game win streak to start the season before they ran into the Suns in a 130-118 road defeat on Sunday. Stephon Castle led the team with 26 points, seven rebounds and five assists, Keldon Johnson added 19 points off the bench while Harrison Barnes chipped in with 13 points. As a team, the Spurs shot 45 percent from the field e and 10 of 41 from the 3-point line as they got off to a slow start and were always fighting an uphill battle after allowing 39 points in the second quarter.
The Spurs trailed in this one by as many as 31 points before they finished with a flurry of 40 points in the fourth quarter to keep the final scores respectable. Victor Wembenyama has been on fire for the Spurs but finished with just nine points with six turnovers in this contest.
Los Angeles Lakers Betting Preview
Meanwhile, the Los Angeles Lakers have been on fire as they’ve reeled off six wins from their last seven games. They will be eager to build on their current four-game win streak after sneaking past the Trail Blazers in a 123-115 road win on Monday. DeAndre Ayton had his best game for the Lakers with 29 points, 10 rebounds and three blocks, Rui Hachimura added 28 points on 10 of 15 shooting while Nick Smith Jr had a breakout game of 25 points with six assists off the bench.
As a team, the Lakers shot a healthy 58 percent from the field and nine of 23 from the 3-point line as they worked their way back from an early 13-point deficit to stay within striking distance. They poured in 71 points in the fourth quarter to pull off the upset win on the road despite missing Luka Doncic and Austin Reaves who were both rested.
Why the Los Angeles Lakers will win
- The Lakers have won each of their last nine games against Southwest Division opponents.
- The Spurs have lost seven of their last eight games at Crypto.com Arena.
- The Lakers have covered the spread in each of their last eight games as home favorites when playing with a rest disadvantage.
- The Spurs have failed to cover the spread in four of their last five games at Crypto.com Arena when playing with a rest advantage.
Why the San Antonio Spurs will win
- The Spurs have won four of their last five games as road underdogs against Pacific Division opponents following a loss.
- The Lakers have lost nine of their last 11 home games against Spurs teams that held a winning record.
- The Spurs have covered the spread in each of their last 12 road games against Pacific Division opponents following a loss.
- The Lakers have failed to cover the spread in three of their last four home games against Western Conference opponents.
Total Points Facts
- Seven of the Lakers’ last eight games have gone OVER the total points line.
- Each of the Spurs’ last six Wednesday games as underdogs have gone UNDER the total points line.
Lakers vs Spurs Prediction
The Spurs are still missing De’Aaron Fox, Dylan Harper and Jeremy Sochan, while the Lakers should have Austin Reaves and Luka Doncic back in the lineup after being rested on Monday. The Spurs were one of the hottest teams in the league before they got silenced by the Suns in an ugly defeat on Sunday. The Lakers are now one of the form teams in the league after winning without their star players in their last outing. I might have been interested in the Spurs if we were getting more free points, but with the line so short, I am sticking with the Lakers to maintain their momentum with a narrow win here.
