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Pacers vs Pistons Prediction 11/24/25 NBA Picks Today

Detroit Pistons (14-2) vs. Indiana Pacers (2-14)
November 24, 2025 7:00 pm EDT
The Line: Indiana Pacers +9.5; Over/Under: 234.5
(Get latest betting odds)

The Detroit Pistons and Indiana Pacers meet Monday in NBA action at the Gainbridge Fieldhouse. Here’s a Pacers vs Pistons Prediction. This article will include a Pacers vs Pistons Pick.

Detroit Pistons Betting Preview

The Detroit Pistons beat the Hawks and Bucks, and they play the Celtics next. The Pistons have won 12 straight games.

The Detroit Pistons are averaging 118.9 points on 48.1 percent shooting and allowing 112.1 points on 43.9 percent shooting. Cade Cunningham is averaging 27.3 points and 5.4 rebounds, while Jalen Duren is averaging 20.6 points and 1.8 assists. Tobias Harris is the third double-digit scorer and Ausar Thompson is grabbing 6.2 rebounds. The Detroit Pistons are shooting 34.6 percent from beyond the arc and 74.2 percent from the free-throw line. The Detroit Pistons are allowing 35.3 percent shooting from deep and are grabbing 46.9 rebounds per game.

Indiana Pacers Betting Preview

The Indiana Pacers lost to the Cavs, beat the Hornets, and they play the Raptors next. The Pacers have lost 14 of their last 16 games.

The Indiana Pacers are averaging 108.7 points on 40.1 percent shooting and allowing 123.2 points on 48.4 percent shooting. Bennedict Mathurin is averaging 31 points and 7 rebounds, while Pascal Siakam is averaging 24.6 points and 7.1 rebounds. Andrew Nembhard is the third double-digit scorer, and Aaron Nesmith is grabbing 4.5 rebounds. The Indiana Pacers are shooting 30 percent from beyond the arc and 77.2 percent from the free-throw line. The Indiana Pacers are allowing 33 percent shooting from deep and are grabbing 46.8 rebounds per game.

Why the Indiana Pacers will win

  • The Pacers have won each of their last six home games against Central Division opponents following a loss.
  • The Pistons have lost 15 of their last 17 games at Gainbridge Fieldhouse following a win.
  • The Pacers have covered the spread in five of their last six games at Gainbridge Fieldhouse when playing with a rest advantage.
  • The Pistons have failed to cover the spread in eight of their last 10 games at Gainbridge Fieldhouse following a win.

Why the Detroit Pistons will win

  • The Pistons have won each of their last 12 games.
  • The Pacers have lost each of their last six games when playing with a rest advantage.
  • The favorites have covered the spread in eight of the last nine games between the Pistons and Pacers.
  • The Pacers have failed to cover the spread in seven of their last eight games following a loss.

Total Points Facts

  • Seven of the Pacers’ last eight home games against the Pistons have gone OVER the total points line.
  • Five of the Pistons’ last six games have gone OVER the total points line.

Indiana Pacers Player Facts

  • Andrew Nembhard ranks 1st in the Eastern Conference amongst qualified players for FT% (93.9%) this season.
  • Pascal Siakam is one of only six qualified players in the league to be leading their team in points (24.8), rebounds (7.0) and assists (4.9) per game this season.

Detroit Pistons Player Facts

  • Cade Cunningham has recorded 8+ assists in nine consecutive appearances – longest active streak of any player in the league.
  • Jalen Duren ranks 1st in the Eastern Conference amongst qualified players for FG% (67.5%) this season.

Matchup/League Facts

  • The Pacers rank 30th in the league for steals per game this season (6.5).
  • The Pacers rank 30th in the league for field goal percentage this season (41.1%).
  • The Pistons rank 1st in the league for opponent assists per game this season (23.3).
  • The Pistons rank 1st in the league for Q2 win percentage this season (81.3%).

Pacers vs Pistons Injury Report

The Pacers will be without Tyrese Haliburton, Obi Toppin, Kam Jones, Aaron Nesmith, Johnny Furphy, and Quenton Jackson.

The Pistons will be without Marcus Sasser and Bobi Klintman.

Pacers vs Pistons Prediction

The Pistons have not only won 12 straight games, but they’re 12-4 ATS on the season. There’s no reason to step in front of the Pistons right now. The Pacers continue to lose, they’re 7-9 ATS on the season, and they’re as banged up as any team in the league. Already 12 games below a .500 record and guys still on the injury report, at this point the Pacers should probably be in a tank mode. Get guys healthy next year, snag a top-three pick, and the Pacers are in business. As for this game, give me the Pistons and the chalk.

Randy Chambers's Free Pick: Detroit Pistons -9.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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