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Trail Blazers vs Spurs Prediction 11/26/25 NBA Picks Today

San Antonio Spurs (11-5) vs. Portland Trailblazers (8-10)
November 26, 2025 10:00 pm EDT
The Line: Portland Trailblazers -2.5; Over/Under: 238.5
(Get latest betting odds)

The San Antonio Spurs invade the Moda Center to take on the Portland Trail Blazers on Wednesday night. Here’s a Trail Blazers vs Spurs Prediction. This article will include a Trail Blazers vs Spurs Pick.

San Antonio Spurs Betting Preview

The San Antonio Spurs have been in pretty good form as they’ve won six of their last nine games overall. They will be looking to bounce back here after having their three-game win streak halted by the Suns in a 111-102 road defeat on Sunday. De’Aaron Fox led the team with 26 points on five of 11 shooting, Devin Vassell added 17 points while Keldon Johnson chipped in with 14 points, six rebounds and two assists off the bench.
As a team, the Spurs shot just 42 percent from the field and 10 of 34 from the 3-point line as they got off to a quick start and took the lead into halftime. But that all changed in the third quarter where the Spurs leaked 37 points to trail the rest of the way. Julian Champagnie shot just three of 14 from the field for his 10 points while David Garcia finished scoreless on zero of four shooting.

Portland Trail Blazers Betting Preview

Meanwhile, the Portland Trail Blazers have been struggling for consistency as they’ve lost seven of their last 10 games overall, but they will be eager to build some momentum after taking down the Bucks in a 115-103 road win on Monday. Jerami Grant led the team with 35 points on eight of 18 shooting, Deni Avdija added 22 points with five assists while Donovan Clingan chipped in with 14 points, 11 rebounds and four assists.
As a team, the Trail Blazers shot 46 percent from the field and 18 of 43 from the 3-point line as they kept a lid on the Bucks’ starters. They led this one by as many as 33 points before they took their foot off the gas with the game in garbage time.

Why the Portland Trail Blazers will win

  • The Spurs have lost seven of their last eight games at Moda Center following a road loss.
  • The home team has won each of the Spurs’ last four games.
  • The Spurs have failed to cover the spread in each of their last seven road games against Western Conference opponents that held a losing record.
  • The Trail Blazers have covered the spread in 13 of their last 14 games when playing with a rest disadvantage.

Why the San Antonio Spurs will win

  • The Trail Blazers have lost each of their last seven games against the Spurs after winning as underdogs.
  • The Spurs have won each of their last seven night games against Northwest Division opponents that held a losing record.
  • The underdogs have covered the spread in each of the Trail Blazers’ last seven games at Moda Center.
  • The Trail Blazers have failed to cover the spread in each of their last six games as favorites.

Total Points Facts

  • Each of the Trail Blazers’ last seven games as favorites have gone OVER the total points line.
  • Each of the Spurs’ last four games as road underdogs have gone UNDER the total points line.

Portland Trail Blazers Player Facts

  • Donovan Clingan is one of only five players in the league to have recorded 20+ rebounds in a game this season.
  • Deni Avdija ranks T7th in the league for fast break points (69) this season.

San Antonio Spurs Player Facts

  • Harrison Barnes is the only qualified player in the league shooting at least 50% from the field, 40% from three and 90% from the free-throw line this season.
  • De’Aaron Fox is one of only 15 qualified Guards in the league shooting at least 50% from the field this season.

Matchup/League Facts

  • The Trail Blazers rank 30th in the league for opponent steals per game this season (10.8).
  • The Trail Blazers have recorded the largest comeback win from a Q1 deficit this season – trailed by 20 points vs Thunder on November 5.
  • The Spurs rank 1st in the league for Q1 opponent points per game this season (25.6).
  • The Spurs have missed the playoffs in six consecutive seasons – second-longest active streak in the NBA.

Trail Blazers vs Spurs Prediction

The Spurs are still shorthanded with Victor Wembenyama, Stephon Castle and Jordan McLaughlin out, while the Trail Blazers have ruled out Jrue Holiday and Scott Henderson again with Shaedon Sharpe listed as questionable. The Spurs have been a team on the rise despite the injury to Wembenyama and they were playing great basketball before they ran into a red-hot Suns in their last outing. They will like their chances against this banged up Trail Blazers squad, who are only 3-4 at home this season. Give me the Spurs to pull off the minor upset on the road.

Peter Tran's Free Pick: San Antonio +2.5

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Peter Tran

Peter Trans is an acclaimed Expert NBA Handicapper, renowned for his insightful analysis and predictions in the world of professional basketball. With a keen eye for detail and a deep understanding of the game, Peter has established himself as a trusted authority among basketball enthusiasts and bettors alike. His expertise is showcased on SportsChatPlace.com, where he provides in-depth game analyses, betting tips, and forecasts that are both highly informative and remarkably accurate.

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