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Los Angeles Rams vs Arizona Cardinals 10/3/21 NFL Picks, Odds, Predictions

Arizona Cardinals (3-0) vs. Los Angeles Rams (3-0)
October 3, 2021 4:05 pm EDT
The Line: Los Angeles Rams -6 / Arizona Cardinals +6; Over/Under: -54.5
(Get latest betting odds)

The Arizona Cardinals and the Los Angeles Rams meet in an NFC West division matchup at SoFi Stadium in NFL action on Sunday afternoon.

The Arizona Cardinals will look to add on to their 31-19 win over Jacksonville last time out. Kyler Murray has thrown for 1,005 yards, 7 touchdowns and 4 interceptions on 76.5% passing while Chase Edmonds and James Conner each have 100+ rushing yards. Christian Kirk leads the Cardinals in receiving with 239 receiving yards while Rondale Moore, A.J. Green, DeAndre Hopkins, Edmonds and Maxx Williams each have 100+ receiving yards as well this season. Defensively, Isaiah Simmons leads the Cards with 23 total tackles and an interception while while Byron Murphy Jr. has a pair of interceptions and Chandler Jones has a team-high 5 sacks.

The Los Angeles Rams will look to build on their 34-24 win over Tampa bay last time out. Matthew Stafford leads the Rams with 942 passing yards 9 touchdowns and an interception on 70.2% passing while Darrell Henderson Jr. and Sony Michel each have 100+ rushing yards. Cooper Kupp leads the Rams’ receivers with 25 catches for 367 yards and 5 TDs while DeSean Jackson, Van Jefferson, Robert Woods and Tyler Higbee all have 100+ receiving yards this season. On defense, Kenny Young has a team-high 25 total tackles while Aaron Donald, Leonard Floyd and Justin Hollins each have a pair of sacks.

Arizona is 12-5-2 ATS in their last 19 road games and 8-2 ATS in their last 10 games in October while the under is 5-0 in their last 5 games as a road underdog. Los Angeles is 9-3-1 ATS in their last 13 games as a home favorite and 10-4-1 ATS in their last 15 division games while the over is 5-0 in their last 5 games overall.

Call it an obvious play, call it square, but I’m leaning towards the over here. These are two of the more electric and talked-about offensive units in the NFL and not just the NFC, and I just think that this is shaping up to be a track meet from start to finish. Give me the over here.

Chris Ruffolo's Free Pick: Over 54.5

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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