Arizona Cardinals vs LA Chargers Prediction 10-21-24 NFL Picks

LA Chargers (3-2) vs. Arizona Cardinals (2-4)
October 21, 2024 9:00 pm EDT
The Line: Arizona Cardinals +2.5; Over/Under: +44.5
(Get latest betting odds)

In this article, we will formulate an Arizona Cardinals vs LA Chargers prediction for this NFL game on Monday, October 21st at State Farm Stadium in Glendale, Arizona. Let’s take a look at the prediction for this Week 7 matchup.

Arizona Cardinals Betting Preview

The Arizona Cardinals are 2-4 this year after they lost to Green Bay by a score of 34-13 in their last game. Arizona allowed the first 24 points in the game and never got back into it. The Cardinals were outgained by a total of 437-303, lost the turnover battle 3-1, and went 4-10 on third down in the game. Kyler Murray threw for 214 yards and one touchdown, while Trey McBride caught eight passes for 96 yards.

Arizona also has losses against Buffalo, Detroit, and Washington, but they do have wins against the Rams and 49ers. The Arizona offense has scored 22.2 points per game with 187 passing yards and 145.2 rushing yards per game, while the defense has allowed 27.2 points per game this season. The Cardinals have gone 40.6% on third down and 3-7 on fourth down so far this season. Kyler Murray has completed 68.2% of his passes for 1,186 yards, eight touchdowns, and two interceptions, while James Conner has rushed for 403 yards and three scores.

LA Chargers Betting Preview

The Los Angeles Chargers are 3-2 this season after they defeated Denver by a score of 23-16 in their last game. Los Angeles led 23-0 after three quarters and they cruised to the win but did allow Denver to make the score look much closer than it was. The Chargers outgained Denver by a total of 350-316, won the turnover battle 2-0, and went 11-18 on third down in the game. Justin Herbert threw for 237 yards and one touchdown, while JK Dobbins rushed for 96 yards and one score.

Los Angeles also has wins against Las Vegas and Carolina, but they do have two losses against Pittsburgh and Kansas City. The LA offense has scored 18.2 points per game with 153.2 passing yards and 127.8 rushing yards per game, while the defense has allowed 13.2 points per game this season. The Chargers have gone 42.5% on third down and 0-1 on fourth down through five games. Justin Herbert has completed 64% of his passes for 815 yards, six touchdowns, and one interception, while Ladd McConkey has caught 19 passes for 219 yards and two scores.

Why the Chargers will beat the Cardinals

The Cardinals have lost each of their last six home games against AFC opponents.
The Chargers have won each of their last five games against the Cardinals following a win.
The Chargers have covered the spread in each of their last six October road games against NFC opponents.
The Cardinals have failed to cover the spread in each of their last four Monday games played on the West Coast.
The Cardinals have lost the first half in each of their last seven games as home underdogs.
The Chargers have scored the first touchdown in nine of their last 10 Monday games played on the West Coast.
The Cardinals have lost the first quarter in each of their last four Week 7 games.

Total Points Facts

Each of the Cardinals’ last eight games at State Farm Stadium following a loss have gone OVER the total points line.
Each of the Chargers’ last seven Monday games played on the West Coast has gone UNDER the total points line.

Arizona Cardinals Player Prop Facts

Kyler Murray has recorded 239+ passing yards in seven of his eight previous October home appearances.
James Conner has recorded 86+ rushing yards in four of the Cardinals’ last five games following a loss.
James Conner has recorded 14+ receiving yards in each of his last nine appearances against AFC West opponents.
James Conner has recorded 83+ rushing and receiving yards in each of the Cardinals’ last seven games following a loss.
James Conner has scored at least one touchdown in each of his five previous home appearances against AFC West opponents.
Kyler Murray has thrown three touchdowns in each of the Cardinals’ last two games following a road loss.
Kyler Murray has recorded 21+ completions in seven of the Cardinals’ last eight games as underdogs.
Jalen Thompson is just one away from 10 career interceptions.

Los Angeles Chargers Player Prop Facts

Justin Herbert has recorded 228+ passing yards in each of the Chargers’ last 11 road games as slight favorites (<-3.5 points).
Justin Herbert has recorded 11+ rushing yards in each of the Chargers’ last five road games against NFC opponents.
Will Dissly has recorded 13+ receiving yards in each of his last six appearances.
Quentin Johnston has recorded 34+ rushing and receiving yards in each of the Chargers’ last four games following a win.
J.K. Dobbins has scored a touchdown in each of his last four appearances with his team as a favorite.
Justin Herbert has thrown two or more touchdowns in each of the Chargers’ last eight games against NFC opponents.
Justin Herbert has recorded 21+ completions in each of the Chargers’ last 11 road games as slight favorites (<-3.5 points).
Asante Samuel Jr. is just one away from 10 career interceptions (including playoffs).

Matchup/League Facts

Heading into Week 7, the Cardinals rank 32nd in the NFL in punt return yards per game (6.8) this season.
Heading into Week 7, the Cardinals rank T2nd in the NFL in Q4 win percentage (66.7) this season.
Heading into Week 7, the Chargers rank 1st in the NFL in points allowed per game (13.2) this season.
Heading into Week 7, the Chargers rank 32nd in the NFL in Q3 points per game (1.8) this season.