New Orleans Saints vs LA Chargers
August 10, 2025 4:05 pm EDT
The Line: Saints -1; Over/Under: 36.5
(Get latest betting odds)
In this article we will formulate a Chargers vs Saints prediction for this NFL game on Sunday, August 10th at SoFi Stadium in Inglewood, California. Let’s take a look at the prediction for this week one matchup in the preseason.
Los Angeles Chargers Betting Preview
The Los Angeles Chargers are 1-0 this preseason after they defeated Detroit by a score of 34-7 in the Hall of Fame game. Los Angeles jumped out to a 14-0 lead in the first quarter, which was cut to 14-7 in the second, before they pulled away in the blowout win. The Chargers added two field goals in the third quarter and scored a touchdown late in the fourth to seal the victory. Los Angeles out gained Detroit by a total of 261-197, went 4-13 on third down, and won the turnover battle 5-0 in the game. Trey Lance went 13-20 for 120 yards and two touchdowns, while DJ Uiagalelei went 2-3 with 25 yards in the game. Kimani Vidal rushed for 37 yards and two scores, while KeAndre Lambert-Smith caught two passes for 43 yards and a touchdown. Emany Johnson led the defense with seven tackles, while Morris-Brash and Edwards each added a sack.
Los Angeles went 1-2 in the preseason last year, which was second best in the AFC West. The Chargers lost their first two games against the Seahawks and Rams by scores of 16-3 and 13-9, but they did win the finale by a score of 26-19 against the Cowboys. Justin Herbert will not be playing in this game and it doesn’t sound like Heinicke will play, so we should see plenty of Trey Lance once again.
New Orleans Saints Betting Preview
The New Orleans Saints went 5-12 last year and they finished tied for third in the NFC South standings with the Panthers. New Orleans started the season with two straight wins, but they lost the next seven games, which set the tone for the disappointing season. The Saints picked up wins against the Panthers, Cowboys, Falcons, Browns, and Giants, while they lost to the Eagles, Falcons, Chiefs, Buccaneers (2), Broncos, Chargers, Panthers, Rams, Commanders, Packers, and Raiders. New Orleans scored 19.9 points per game in 2024, which was ranked 24th in the NFL, while they allowed 23.4 points against per game, which was 19th.
New Orleans went 1-2 in the preseason last year, which was tied for second with the Panthers in the NFC South. The Saints beat the Cardinals by a score of 16-14 in their first game, but they lost to the 49ers by a score of 16-10 and the Titans by a score of 30-27. New Orleans is expected to play Spencer Rattler, Tyler Shough, and Jake Haener at quarterback, as they have a quarterback competition this year.
Chargers vs Saints Prediction
These two teams come into this matchup looking to start the preseason on a positive note, but I think New Orleans has more to play for. The Saints are going to feature at least three quarterbacks in this game and all three will be looking to make big plays and push the ball down the field. The Chargers will have Trey Lance under center, who played well in that first game against the Lions. I think we are going to see both offenses look strong, so I like the over here.
