Chiefs vs Chargers Prediction 12/14/25 NFL Picks Today

The Los Angeles Chargers and Kansas City Chiefs meet Sunday in NFL action at Arrowhead Stadium. Here’s a Chiefs vs Chargers Prediction. This article will include a Chiefs vs Chargers Pick.

Los Angeles Chargers Betting Preview

The Los Angeles Chargers beat the Raiders and Eagles, and they play the Cowboys next. The Los Angeles Chargers have won 5 of their last 6 games. Justin Herbert is completing 65.6 percent of his passes for 2,981 yards, 22 touchdowns, and 11 interceptions. Ladd McConkey and Keenan Allen have combined for 1,339 receiving yards and 9 touchdowns, while Quentin Johnston has 39 receptions.

The Los Angeles Chargers ground game is averaging 125.7 yards per contest, and Kimani Vidal leads the way with 587 yards and 3 touchdowns. Defensively, Los Angeles is allowing 20.8 points and 282.2 yards per game. Daiyan Henley leads the Los Angeles Chargers with 82 tackles, Tuli Tuipulotu has 10 sacks and Tony Jefferson has 4 interceptions.

Kansas City Chiefs Betting Preview

The Kansas City Chiefs lost to the Cowboys and Texans, and they play the Titans next. The Kansas City Chiefs have lost 4 of their last 5 games. Patrick Mahomes is completing 63.1 percent of his passes for 3,398 yards, 22 touchdowns, and 10 interceptions. Rashee Rice and Travis Kelce have combined for 1,247 receiving yards and 10 touchdowns, while Hollywood Brown has 42 receptions.

The Kansas City Chiefs ground game is averaging 118.9 yards per contest, and Kareem Hunt leads the way with 545 yards and 8 touchdowns. Defensively, Kansas City is allowing 19.4 points and 303.7 yards per game. Nick Bolton leads the Kansas City Chiefs with 112 tackles, George Karlaftis has 6 sacks and Jaylen Watson has 2 interceptions.

Why the Kansas City Chiefs will win

• The Chiefs have won each of their last 13 games following a home loss.
• The Chargers have lost each of their last eight games as road underdogs against AFC opponents.
• The home team has covered the spread in each of the Chargers’ last six games.
• The Chargers have failed to cover the spread in each of their last four road games.
• The Chiefs have won the first quarter in each of their last six Week 15 home games.
• The Chiefs have scored the first touchdown in 11 of their last 12 Week 15 games.
• The Chiefs have won the first half in each of their last 11 Week 15 home games.

Why the Los Angeles Chargers will win

• The Chargers have won each of their last six games against AFC West opponents.
• The Chiefs have lost five of their last six games as favorites against opponents on a winning streak.
• The Chiefs have failed to cover the spread in each of their last nine games without Isiah Pacheco.
• The Chargers have covered the spread in each of their last eight games against AFC West opponents.
• The Chiefs have lost the first quarter in each of their last four games as favorites against AFC opponents.
• The Chargers have scored the first touchdown in each of their last five games as underdogs following a home win.
• The Chiefs have lost the first half in each of their last three games as moderate favorites (-3.5 to -7.0 points).

Total Points Facts

• Each of the Chiefs’ last nine games at GEHA Field at Arrowhead Stadium following a loss have gone UNDER the total points line.
• Each of the last eight games between teams from the same division have gone OVER the total points line.
• Each of the Chargers’ last six Sunday games as underdogs have gone UNDER the total points line.

Kansas City Chiefs Player Prop Facts

• Kareem Hunt has scored a touchdown in each of the Chiefs’ last four games against teams that held a winning record.
• Isiah Pacheco has recorded 43+ rushing yards in each of his six previous appearances following a home loss.
• Travis Kelce has recorded 44+ receiving yards in each of his last 13 appearances against AFC West opponents.
• Xavier Worthy has recorded 46+ rushing and receiving yards in each of the Chiefs’ last seven regular season home games against AFC opponents.
• Heading into Week 15, Isiah Pacheco ranks 4th in the league amongst qualified players for broken tackle percentage (45.0%) this season.

Los Angeles Chargers Player Prop Facts

• Quentin Johnston has scored a touchdown in each of his last three appearances against teams that held a losing record.
• Omarion Hampton has recorded 56+ rushing yards in each of his last three appearances following a win.
• Omarion Hampton has recorded 67+ rushing and receiving yards in each of his last four appearances.
• Tyler Conklin has recorded 50+ receiving yards in each of his last four appearances with his team as an underdog against AFC West opponents.
• Heading into Week 15, Cameron Dicker ranks T1st in the NFL in made field goals (31) this season.

Matchup/League Facts

• Heading into Week 15, the Chiefs rank 1st in the NFL in 4th down percentage against (27.8%) this season.
• Heading into Week 15, the Chiefs have suffered the equal-most losses by a margin of 10 points or less this season (7).
• Chargers – two different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 15.
• Chargers – two different players have recorded 90+ rushing yards in a game this season – equal-most in the NFL, heading into Week 15.

Chiefs vs Chargers Prediction

The Chiefs are going to get the benefit of the doubt with their season on the line, as they have to win out to have a real shot of getting in the playoffs. The Chiefs have won 7 of the last 8 games against the Chargers, and their pressure style defense should have a field day against a banged up Chargers offensive line. We saw what the Eagles did to the Chargers last week, and that was with no Jalen Carter.

However, I’m not laying this many points with a Chiefs team that has similar issues on the offensive line. Since November, the Chiefs are 0-5 ATS and 1-4 SU as a favorite. The Chiefs are 4-10 ATS in their last 14 games when favorites of 4 or more points. Also, a lot of people aren’t just saying that the Chargers are a good football team with a talented defense and an offense that would be better if it weren’t for injuries. I have to grab the points with the Chargers in this massive AFC West matchup.