Colts vs Texans Prediction 11/30/25 NFL Picks Today
Houston Texans (6-5) vs. Indianapolis Colts (8-3)
November 30, 2025 1:00 pm EDT
The Line: Indianapolis Colts -4.5; Over/Under: 44.5
(Get latest betting odds)
The Houston Texans and Indianapolis Colts meet Sunday in NFL action at Lucas Oil Stadium. Here’s a Colts vs Texans Prediction. This article will include a Colts vs Texans Pick.
Houston Texans Betting Preview
The Houston Texans beat the Bills and Titans, and play the Chiefs next. The Houston Texans have won 4 of their last 5 games. C.J. Stroud is completing 66.5 percent of his passes for 1,702 yards, 11 touchdowns, and 5 interceptions. Nico Collins and Dalton Schultz have combined for 1,194 receiving yards and 5 touchdowns, while Jayden Higgins has 27 receptions.
The Houston Texans ground game is averaging 107.6 yards per contest, and Nick Chubb leads the way with 435 yards and 2 touchdowns. Defensively, Houston is allowing 16.5 points and 264.3 yards per game. Azeez Al-Shaair leads the Houston Texans with 71 tackles, Danielle Hunter has 11 sacks and Calen Bullock has 4 interceptions.
Indianapolis Colts Betting Preview
The Indianapolis Colts lost to the Chiefs, beat the Falcons, and they play the Jaguars next. The Indianapolis Colts have won 5 of their last 7 games. Daniel Jones is completing 69.1 percent of his passes for 2,840 yards, 17 touchdowns, and 7 interceptions. Tyler Warren and Alex Pierce have combined for 1,273 receiving yards and 4 touchdowns, while Micheal Pittman Jr. has 59 receptions.
The Indianapolis Colts ground game is averaging 138.8 yards per contest, and Jonathan Taylor leads the way with 1,197 yards and 15 touchdowns. Defensively, Indianapolis is allowing 20.8 points and 342.7 yards per game. Nick Cross leads the Indianapolis Colts with 77 tackles, Laiatu Latu has 6 sacks and Mekhi Blackmon has 2 interceptions.
Why the Indianapolis Colts will win
- The Colts have won each of their last seven games at Lucas Oil Stadium.
- The Texans have lost each of their last six road games against teams that held a winning record.
- The Colts have covered the spread in seven of their last eight games against AFC South opponents.
- The Texans have failed to cover the spread in each of their last five games as underdogs following a home win.
- The Colts have won the first quarter in nine of their last 10 Sunday games against the Texans.
- The Colts have won the first half in each of their last six Week 13 home games against AFC opponents.
- The Colts have scored the first touchdown in each of their last nine games.
Why the Houston Texans will win
- The Texans have won 12 of their last 13 road games against AFC South opponents.
- The Colts have lost five of their last six November games at Lucas Oil Stadium.
- The Texans have covered the spread in eight of their last nine games as road underdogs against AFC South opponents.
- The Colts have failed to cover the spread in five of their last six November home games against AFC opponents.
- The underdogs have won the first quarter in four of the last five games between the Texans and Colts.
- The Texans have won the first half in six of their last seven Sunday games against teams that held a winning record.
Total Points Facts
- Eight of the Texans’ last nine Week 13 games have gone UNDER the total points line.
- Each of the Colts’ last four games against AFC South opponents have gone OVER the total points line.
- Four of the last five games between teams from the same division have gone UNDER the total points line.
Indianapolis Colts Player Prop Facts
- Jonathan Taylor has scored the first touchdown in four of the Colts’ last five November games as favorites.
- Jonathan Taylor has scored two or more touchdowns in four of the Colts’ last five games as moderate favorites (-3.5 to -7.0 points).
- Daniel Jones has recorded 22+ completions in three of his last four November appearances with his team as a favorite.
- Jonathan Taylor has recorded 96+ rushing yards in each of the Colts’ last six games as moderate favorites (-3.5 to -7.0 points).
- Daniel Jones has recorded 255+ passing yards in four of the Colts’ last five games.
- Josh Downs has recorded 34+ receiving yards in each of his last eight appearances against AFC South opponents.
- Jonathan Taylor has scored at least one touchdown in each of his eight previous appearances against the Texans.
- Jonathan Taylor has recorded 122+ rushing and receiving yards in seven of his last eight appearances with the Colts as home favorites against AFC South opponents.
- Jonathan Taylor has scored the last touchdown in three of the Colts’ last four November games as favorites.
- Heading into Week 13, Jonathan Taylor ranks 1st in the NFL in rushing yards (1197) this season.
Houston Texans Player Prop Facts
- Nick Chubb has recorded 22+ rushing yards in each of his last 11 Sunday appearances with his team as an underdog.
- C.J. Stroud has recorded 247+ passing yards in six of his eight previous November appearances.
- Joe Mixon has scored a touchdown in each of his last five appearances against the Colts.
- Christian Kirk has recorded 22+ receiving yards in each of his last 29 appearances with his team as an underdog.
- Christian Kirk has recorded 25+ rushing and receiving yards in each of his last 29 appearances with his team as an underdog.
- Davis Mills has recorded 22+ completions in four of his last five appearances as a starter.
- Heading into Week 13, Ka’imi Fairbairn ranks T1st in the NFL in made field goals (25) this season.
Matchup/League Facts
- Colts – four different players have recorded 2.0 sacks or more in a game this season – equal-most in the NFL, heading into Week 13.
- Heading into Week 13, the Colts rank 1st in the NFL in points per game (31.0) this season.
- Heading into Week 13, the Texans rank 1st in the NFL in yards allowed per game (264.3) this season.
- Heading into Week 13, the Texans rank 1st in the NFL in 1st downs against (175) this season.
Colts vs Texans Prediction
I’d obviously like the Texans more if Stroud was playing, but he’s still in concussion protocol at the time of this writing. I’m still grabbing the points. The Texans’ defense is the best in the league and good enough to keep them in this game. We know Jones can get rattled at times, and the Colts weren’t able to have success running last week. It’s going to be tough sledding here against this Houston defensive front.
The Colts are also 28th in passing defense, so if there was a game for potentially Davis Mills to get comfortable, it would be this one. The underdog has covered 5 of the last 6 games between the Texans and Colts. Give me the points.
