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Eagles vs 49ers Pick – NFL Predictions & Odds 1/29/23

San Francisco 49ers (15-4) vs. Philadelphia Eagles (15-3)
January 29, 2023 3:00 pm EDT
The Line: Philadelphia Eagles -2.5 / San Francisco 49ers +2.5; Over/Under: 45.5
(Get latest betting odds)

The San Francisco 49ers and Philadelphia Eagles clash Sunday in NFL NFC Championship action at Lincoln Financial Field. Let’s dive into the odds, injuries, matchup history and make a prediction for this game.

49ers vs Eagles Odds

The Eagles are 2.5 point favorites and have a ML price of -135. The over / under is set at 45.5 points.

49ers vs Eagles Injuries

49ers cornerback Ambry Thomas is questionable with an ankle injury, while running backs Christian McCaffrey and Elijah Mitchell are probable. Eagles wide receiver A.J. Brown is questionable with a hip injury. 

49ers vs Eagles Recent Meeting

The 49ers beat the Eagles, 17-11, in September 2021 as 3 point favorites. The Eagles scored 3 points in the first three quarters and Hurts threw for 190 yards. Jimmy Garoppolo was the quarterback for the 49ers. The Eagles have won 6 of the last 9 meetings against the 49ers, a span that goes back to 2006. 

The 49ers are 5-0 ATS in their last 5 playoff games and 23-8 ATS in their last 31 games overall. The Eagles are 7-3 ATS in their last 10 home games and 1-4 ATS in their last 5 games overall. The over is 4-1 in 49ers last 5 games overall. The under is 4-1 in Eagles last 5 games overall. The 49ers are 3-7 ATS in their last 10 meetings. The favorite is 7-3 ATS in their last 10 meetings.

Randy’s Free Pick

The Philadelphia Eagles look to be a well oiled machine on both sides of the ball, and they should be favored at home. However, we’re getting free points with the 49ers, a team that hasn’t lost a game since October 23. Brock Purdy is taking what defenses give him while the playmakers make plays, and that 49ers defense is something special. This is going to be a bloodbath defensively on both sides. It could come down to the wire. I want the points in my pocket for this toss up.

Randy Chambers's Free Pick: San Francisco 49ers +2.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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