Texans vs Cardinals Prediction 12/14/25 NFL Picks Today
Arizona Cardinals (3-10) vs. Houston Texans (8-5)
December 14, 2025 1:00 pm EDT
The Line: Houston Texans -9.5; Over/Under: 42.5
(Get latest betting odds)
The Arizona Cardinals and the Houston Texans meet in week 15 NFL action from NRG Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Texans vs Cardinals Prediction.
Arizona Cardinals Recap
The Arizona Cardinals come into this game looking to bounce back from a 45-17 loss at the hands of the Los Angeles Rams last time out to sit at 3-10 this season. After this game, Arizona will head home for a game against the Atlanta Falcons.
Cardinals Lose 5 In A Row
Jacoby Brissett has thrown for 2,459 yards, 15 touchdowns and 5 interceptions on 66.2% passing while Bam Knight has rushed for a team-high 271 yards and 4 TDs. Emari Demercado also has 241 rushing yards while Trey McBride has 93 catches for 937 yards and 8 touchdowns and Marvin Harrison Jr. has 40 catches for 594 yards and 4 TDs. Michael Wilson has 61 catches for 712 yards and 3 TDs and another five Cardinals also have 150+ receiving yards as well this season. On defense, Budda Baker also has a team-high 93 total tackles while Josh Sweat has a team-high 11 sacks and Calais Campbell has 5.5 sacks. As a unit, Arizona’s defense has combined for 24 sacks and 9 interceptions so far this season.
Why the Arizona Cardinals will win
- The Texans have lost three of their last four games as heavy favorites (>-7.0 points).
- The underdogs have won each of the Texans’ last three games.
- The Cardinals have covered the spread in each of their last eight road games following a loss.
- The Texans have failed to cover the spread in eight of their last nine December games against NFC opponents.
Arizona Cardinals Player Prop Facts
- Trey McBride has scored a touchdown in each of the Cardinals’ last six games as road underdogs.
- Jacoby Brissett has recorded 258+ passing yards in each of the Cardinals’ last eight games.
- Jacoby Brissett has recorded 25+ completions in each of the Cardinals’ last four games.
- Michael Carter has recorded 18+ receiving yards in each of his last seven appearances following a loss.
- Michael Carter has recorded 34+ rushing and receiving yards in each of his seven previous appearances against AFC South opponents.
- Michael Carter has recorded 25+ rushing yards in each of his last four appearances against AFC opponents.
- Heading into Week 15, Trey McBride ranks T1st in the NFL in receptions (93) this season.
Houston Texans Recap
The Houston Texans come into this game looking to add on to their 20-10 win over Kansas City last time out to sit at 8-5 this season. After this game, Houston will take on the Las Vegas Raiders at home.
Texans Win 5 In A Row
C.J. Stroud has 2,181 yards, 12 touchdowns and 6 interceptions on 64.3% passing while Davis Mills has thrown for 879 yards, 5 TDs and an INT on 58.7% passing. Nick Chubb has rushed for 472 yards and 3 touchdowns as well this season. Woody Marks also has 554 rushing yards and 2 TDs while Nico Collins leads Houston’s receivers with 916 receiving yards and 4 TDs and Dalton Schultz has 62 grabs for 574 yards. Xavier Hutchinson has 303 receiving yards and 3 TDs and Jayden Higgins has 393 receiving yards as well this season. Three more Texans have 150+ receiving yards as well this season. On defense, Azeez Al-Shaair leads the Texans with 84 total tackles while Jalen Pitre has 4 INTs and Will Anderson Jr. has 10.5 sacks. Danielle Hunter also has 11 sacks while Calen Bullock has 4 interceptions and Derek Stingley Jr. and Kamari Lassiter each have 3 interceptions as well this season. As a unit, Houston’s defense has combined for 36 sacks and 15 interceptions up to this point in the year.
Why the Houston Texans will win
- The Cardinals have lost each of their last 12 games against opponents on a winning streak.
- The home team has won each of the six previous games between the Cardinals and Texans.
- The Texans have covered the spread in each of their last seven Week 15 games.
- The Cardinals have failed to cover the spread in each of their last four games following a Division game.
Houston Texans Player Prop Facts
- Nico Collins has scored the first touchdown in three of his last four home appearances against NFC opponents.
- C.J. Stroud has recorded 232+ passing yards in five of the Texans’ last six home games against NFC opponents.
- Joe Mixon has scored at least one touchdown in five of his last six appearances against NFC opponents.
- Christian Kirk has recorded 39+ receiving yards in each of his last 15 appearances against NFC opponents.
- Nick Chubb has recorded 32+ rushing and receiving yards in each of his last 34 Sunday home appearances.
- Nick Chubb has recorded 17+ rushing yards in each of his last 47 appearances with his team as a favorite.
- Davis Mills has recorded 22+ completions in four of his last five appearances as a starter.
- Heading into Week 15, Calen Bullock has recorded the equal-most interceptions in a single game this season (2 vs Bills, Week 12).
Total Points Facts
- Seven of the Cardinals’ last eight Sunday games have gone OVER the total points line.
- Each of the Texans’ last five games following a win have gone UNDER the total points line.
Texans vs Cardinals Prediction
I’m on the under in this one. I just think this is setting up for a bit of a letdown spot for Houston after such a big win over Kansas City in primetime last time out. But I also think this Texans defense is legit and is going to hold down Arizona here. We’ve seen 4 straight low-scoring unders for Houston, and I think a 5th could be on the cards here. Give me the under.