Miami Dolphins vs LA Chargers Prediction 10/12/25 NFL Picks Today

The Los Angeles Chargers and the Miami Dolphins meet in week 6 NFL action from Hard Rock Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Chargers vs. Miami Dolphins prediction.

Los Angeles Chargers Recap

The Los Angeles Chargers come into this game looking to bounce back from their 27-10 loss at the hands of the Washington Commanders to sit at 3-2 this season. After this game, the Chargers will head home for a game against the Indianapolis Colts.

Chargers Drop Back-To-Back Games

Justin Herbert has thrown for 1,229 yards, 8 touchdowns and 4 interceptions on 65.7% passing while Omarion Hampton leads Los Angeles in rushing with 314 rushing yards and 2 TDs this season. Quentin Johnston has 377 receiving yards and 4 touchdowns to lead the Chargers’ group while Keenan Allen has 29 catches for 289 receiving yards and 3 touchdowns and Ladd McConkey’s added 21 catches and 213 receiving yards as well. On defense, Daiyan Henley has a team-high 39 total tackles and a pair of sacks while Derwin James Jr. has 37 total tackles including a team-high 34 solo tackles. Tuli Tuipulotu has a team-high 4 sacks while the Chargers’ defensive unit as a whole has combined for 14 sacks and 3 interceptions so far this season. 

Why the Los Angeles Chargers will win

• The Dolphins have lost each of their last 10 games as underdogs against AFC opponents.
• The Chargers have won each of their last four games following a home loss.
• The Dolphins have failed to cover the spread in each of their last seven October games as underdogs.
• The Chargers have covered the spread in 10 of their last 11 games as favorites against AFC opponents.

Los Angeles Chargers Player Prop Facts

• Tyler Conklin has scored a touchdown in three of his last four appearances against AFC East opponents.
• Justin Herbert has recorded 281+ passing yards in five of the Chargers’ last six regular season games against AFC opponents.
• Justin Herbert has recorded 25+ completions in four of the Chargers’ last five regular season games against AFC opponents.
• Will Dissly has recorded 26+ receiving yards in six of his last seven Sunday appearances with the Chargers as favorites.
• Ladd McConkey has recorded 58+ rushing and receiving yards in five of the Chargers’ last six games following a loss.
• Justin Herbert has recorded 24+ rushing yards in five of the Chargers’ last six regular season games.
• Heading into Week 6, Tuli Tuipulotu has recorded the most sacks in a single game this season (4.0 vs Giants, Week 4).

Miami Dolphins Recap

The Miami Dolphins come into this game looking to bounce back from their 27-24 loss to the Carolina Panthers last time out to sit at 1-4 on the year. After this game, Miami will head on the road for a game against the Cleveland Browns.

Dolphins Looking To Rebound

Tua Tagovailoa has thrown for 1,008 yards, 5 touchdowns and 4 interceptions on 69.7% passing while De’Von Achane has rushed for 262 yards as well this season. Jaylen Waddle has a team-high 295 receiving yards and 3 TDs coming on 23 catches while Achane has 25 receptions for 173 yards and 3 touchdowns. On defense, Jordyn Brooks leads the Dolphins with 57 total tackles including 32 solo tackles and 1.5 sacks while Bradley Chubb has a team-high 4 sacks so far this season. As a unit, Miami’s defense has combined for 11 sacks and an interception so far this season.

Why the Miami Dolphins will win

• The Dolphins have won 11 of their last 12 home games against opponents on a losing streak.
• The Chargers have lost seven of their last eight October road games against AFC East opponents.
• The Dolphins have covered the spread in five of their last six Week 6 home games.
• The Chargers have failed to cover the spread in four of their last five Week 6 games.

Miami Dolphins Player Prop Facts

• Jaylen Waddle has recorded 83+ receiving yards in four of his last five Sunday appearances with the Dolphins as home underdogs.
• De’Von Achane has recorded 62+ rushing yards in each of the Dolphins’ last four games played as underdogs on the East Coast.
• De’Von Achane has scored at least one touchdown in each of the Dolphins’ last nine Sunday games played on the East Coast.
• Jaylen Waddle has recorded 83+ rushing and receiving yards in four of his last five Sunday appearances with the Dolphins as home underdogs.
• Heading into Week 6, Jordyn Brooks has recorded the most tackles in a single game this season (18 vs Jets, Week 4).

Total Points Facts

• Each of the Dolphins’ last 11 games played on the East Coast have gone OVER the total points line.
• Each of the Chargers’ last eight Sunday games played on the East Coast have gone UNDER the total points line.
• Each of the last six Sunday games at Hard Rock Stadium have gone OVER the total points line.

Los Angeles Chargers vs. Miami Dolphins Prediction

I’m on the Chargers here. I just think that without Tyreek Hill, that takes away the downfield passing game for Miami and really makes this Dolphins team too one-dimensional for my liking. The Chargers have had a couple of down performances the last couple of weeks, but I think this is a good spot for them to bounce back in an extremely winnable game. Give me the Chargers in this one.