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Panthers vs Seahawks Prediction 12/28/25 NFL Picks Today

Seattle Seahawks (12-3) vs. Carolina Panthers (8-7)
December 28, 2025 1:00 pm EDT
The Line: Carolina Panthers +7; Over/Under: 42.5
(Get latest betting odds)

The Seattle Seahawks and Carolina Panthers meet Sunday in NFL action at Bank of America Stadium. Here’s a Panthers vs Seahawks Prediction. This article will include a Panthers vs Seahawks Pick.

Seattle Seahawks Betting Preview

The Seattle Seahawks beat the Rams and Colts, and they play the 49ers next. The Seahawks have won 9 of their last 10 games. Sam Darnold is completing 67.2 percent of his passes for 3,703 yards, 24 touchdowns, and 13 interceptions. Jaxon Smith-Njigba and Cooper Kupp have combined for 2,195 receiving yards and 12 touchdowns, while AJ Barner has 47 receptions.

The Seattle Seahawks ground game is averaging 116.9 yards per contest, and Kenneth Walker III leads the way with 879 yards and 5 touchdowns. Defensively, Seattle is allowing 18.6 points and 303.2 yards per game. Ernest Jones IV leads the Seattle Seahawks with 116 tackles, Leonard Williams has 7 sacks and Coby Bryant has 4 interceptions.

Carolina Panthers Betting Preview

The Carolina Panthers lost to the Saints, beat the Buccaneers, and they play the Buccaneers next. The Carolina Panthers have split their last 8 games. Bryce Young is completing 63.5 percent of his passes for 2,691 yards, 21 touchdowns, and 9 interceptions. Tetairoa McMillan and Xavier Legette have combined for 1,262 receiving yards and 10 touchdowns, while Jalen Cooker has 25 receptions.

The Carolina Panthers ground game is averaging 123.9 yards per contest, and Rico Dowdle leads the way with 1,007 yards and 6 touchdowns. Defensively, Carolina is allowing 22.5 points and 329.1 yards per game. Christian Rozeboom leads the Carolina Panthers with 104 tackles, Derrick Brown has 5 sacks and Jaycee Horn has 5 interceptions.

Why the Carolina Panthers will win

  • The underdogs have won eight of the Panthers’ last nine games at Bank of America Stadium.
  • The Seahawks have lost each of their last four games following a Division win.
  • The Seahawks have failed to cover the spread in each of their last eight games as favorites following a Division game.
  • The Panthers have covered the spread in each of their last six December games as home underdogs.
  • The Panthers have won the first quarter in three of their last four games as home underdogs against NFC West opponents.
  • The Seahawks have lost the first half in 12 of their last 15 games in December.

Why the Seattle Seahawks will win

  • The Seahawks have won each of their last 13 games as road favorites.
  • The Panthers have lost each of their last six Week 17 games.
  • The Panthers have failed to cover the spread in each of their last six Week 17 games.
  • The Seahawks have covered the spread in seven of their last eight road games following a Division game.
  • The Seahawks have won the first quarter in four of their last five Week 17 games.
  • The Panthers have lost the first half in each of their last eight home games against teams that held a winning record.
  • The Seahawks have scored the first touchdown in eight of their last nine games as favorites against NFC opponents.

Total Points Facts

  • Each of the last eight games between the Seahawks and Panthers have gone OVER the total points line.
  • Each of the Seahawks’ last six games as favorites against the Panthers have gone OVER the total points line.
  • Eleven of the last 14 Sunday games at Bank of America Stadium have gone OVER the total points line.

Carolina Panthers Player Prop Facts

  • Chuba Hubbard has scored a touchdown in five of his last six appearances in day games against teams that held a winning record.
  • Chuba Hubbard has recorded 34+ rushing yards in each of the Panthers’ last 10 games at Bank of America Stadium as moderate underdogs (+3.5 to +7.0 points).
  • Rico Dowdle has recorded 74+ rushing and receiving yards in five of the Panthers’ last six games as underdogs against NFC opponents.
  • Rico Dowdle has recorded 14+ receiving yards in each of the Panthers’ last four games as underdogs.
  • Andy Dalton has recorded 331+ passing yards in three of his last four appearances against the Seahawks.
  • Andy Dalton has recorded 26+ completions in four of his last five appearances with his team as an underdog against NFC West opponents.
  • Heading into Week 17, Mike Jackson ranks T1st in the league for passes defensed (17) this season.

Seattle Seahawks Player Prop Facts

  • Cooper Kupp has scored at least one touchdown in nine of his last 10 appearances on the East Coast.
  • Zach Charbonnet has recorded 44+ rushing yards in each of the Seahawks’ last four December road games against NFC opponents.
  • Sam Darnold has recorded 240+ passing yards in each of his last 11 appearances with his team as a road favorite.
  • Jaxon Smith-Njigba has recorded 92+ receiving yards in each of the Seahawks’ last six Sunday road games.
  • Sam Darnold has recorded 20+ completions in each of his last eight December appearances.
  • Cooper Kupp has recorded 35+ rushing and receiving yards in 16 of his 18 previous appearances against NFC South opponents.
  • Heading into Week 17, Jaxon Smith-Njigba ranks 1st in the NFL in receiving yards (1637) this season.

Matchup/League Facts

  • Panthers – two different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 17.
  • Heading into Week 17, the Panthers are the only team to overturn multiple 12+ point 2nd quarter deficits to win this season.
  • Seahawks – six different players have recorded multi-touchdown games this season – equal-most in the NFL, heading into Week 17.
  • Seahawks – two different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 17.

Panthers vs Seahawks Prediction

The Seahawks are the more trustworthy team as they’ve top-5 in scoring offense and scoring defense, and they’ve had extra time to prepare for this game. I understand why the Seahawks are favored. However, it feels like everybody is waiting for the Panthers to regress, but they’re closing in on a division title.

The Panthers still have a ways to go offensively, and the defense is average at best, but they’re still winning games and are a profitable 9-6 ATS on the season. A touchdown feels a bit rich. Since October, the Panthers are 7-2 ATS and SU as an underdog. The Panthers have covered 9 of their last 12 games when an underdog of 6 or more points. Give me the points with the Panthers.

Randy Chambers's Free Pick: Carolina Panthers +7

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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