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TNF: Seattle Seahawks vs San Francisco 49ers 12/15/22 NFL Picks, Predictions, Odds

San Francisco 49ers (9-4) vs. Seattle Seahawks (7-6)
December 15, 2022 8:15 pm EDT
The Line: Seattle Seahawks +3.5 / San Francisco 49ers -3.5; Over/Under: 43.5
(Get latest betting odds)

The Seattle Seahawks and San Francisco 49ers do battle in week 15 Thursday Night Football NFL action at Lumen Field. The San Francisco 49ers have won 6 straight games. The Seattle Seahawks have lost 3 of their last 4 games.

The San Francisco 49ers have lost 3 of their last 5 road games. Brock Purdy is completing 67.2 percent of his passes for 461 yards, 4 touchdowns and 2 interceptions. Brandon Aiyuk and Deebo Samuel have combined for 1,367 receiving yards and 9 touchdowns, while George Kittle has 42 receptions. The San Francisco 49ers ground game is averaging 130.6 yards per contest, and Christian McCaffrey leads the way with 426 yards and 3 touchdowns. Defensively, San Francisco is allowing 15.2 points and 286.8 yards per game. Dre Greenlaw leads the San Francisco 49ers with 103 tackles, Nick Bosa has 14.5 sacks and Talanoa Hufanga has 4 interceptions.

The Seattle Seahawks have split their last 6 home games. Geno Smith is completing 71.5 percent of his passes for 3,433 yards, 25 touchdowns and 8 interceptions. Tyler Lockett and DK Metcalf have combined for 1,765 receiving yards and 14 touchdowns, while Noah Fant has 37 receptions. The Seattle Seahawks ground game is averaging 111.1 yards per contest, and Kenneth Walker III leads the way with 649 yards and 9 touchdowns. Defensively, Seattle is allowing 25.7 points and 378.7 yards per game. Jordyn Brooks leads the Seattle Seahawks with 141 tackles, Uchenna Nwosu has 9 sacks and Tariq Woolen has 6 interceptions.

The 49ers are 7-3 ATS in their last 10 road games and 4-0 ATS in their last 4 games overall. The Seahawks are 8-2-2 ATS in their last 12 Thursday games and 0-4 ATS in their last 4 games overall. The over is 5-2 in 49ers last 7 games overall. The over is 4-1 in Seahawks last 5 games overall. The 49ers are 2-8-1 ATS in their last 11 meetings in Seattle and 6-15-1 ATS in their last 22 meetings. The home team is 4-1 ATS in their last 5 meetings.

The San Francisco 49ers are the better team obviously, they smoked the Seahawks earlier this season, and they should be favored. The Seattle Seahawks are in a bit of a funk right now and if it weren’t for a late touchdown against the Rams, they’d be riding a 4-game losing streak. With all that said, this is a short week and Thursday night where weird things happen all the time. This will be Brock Purdy’s first road start, and Seattle is still a tough place to play. I’ll take my chances with the points.

Randy Chambers's Free Pick: Seattle Seahawks +3.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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