Astros vs White Sox Prediction 7/26/26 MLB Picks Today

In this article, we will formulate a Astros vs White Sox Prediction for this MLB matchup on Sunday, July 26^th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago White Sox Preview

The Chicago White Sox have a 54-49 record this season and are sitting in the 1st place of the AL Central. They have a 31-19 home record and are coming off a 1-4 home loss against the Astros. They will face the Yankees and the Rays next.

The Chicago White Sox have a .239 batting average this season, .317 OBP and .406 Slugging percentage. Chicago’s pitching staff has a 4.12 ERA and 1.31 WHIP. Sam Antonacci is the team’s best hitter with a .278 batting average. Miguel Vargas leads the team in RBI with 61, while Colson Montgomery adds a team-high 24 home runs.

Erick Fedde (R) is the projected starting pitcher for the Chicago White Sox, and he has a 5-6 record, 4.16 ERA and 1.40 WHIP.

Houston Astros Preview

The Houston Astros have a 52-54 record this season and are sitting in the 2nd place of the AL West. They have a 26-27 away record and are coming off a 4-1 road win against the White Sox. They will face the Angels and the Rangers next.

The Houston Astros have a .242 batting average this season, .316 OBP and .412 Slugging percentage. Houston’s pitching staff has a 4.67 ERA and 1.38 WHIP. Yordan Alvarez is the team’s best hitter with a .325 batting average, leads the team in RBI with 77, and adds a team-high 34 home runs.

Ronel Blanco (R) is the projected starting pitcher for the Houston Astros, and he has a 0-0 record, 7.71 ERA and 1.07 WHIP.

Houston Astros @ the Chicago White Sox Betting Trends: July 26, 2026

• Probable Starting Pitcher: Erick Fedde      Record this season: 5-6      ERA: 4.16
• Home Record: 2-1
• Last 5 against Astros: 0-1

Why the Chicago White Sox will win

• The White Sox have won eight of their last nine games against AL West opponents following a home loss.
• The Astros have lost each of their last three day games against American League opponents.
• The White Sox have covered the run line in each of their last six Sunday home games against AL West opponents.
• The Astros have failed to cover the run line in seven of their last nine day games against AL Central opponents following a road win.
• The Astros have lost the first inning in three of their last four games against AL Central opponents.
• The Astros have trailed after 5 innings in five of their last six day games.
• The Astros have trailed after 3 innings in five of their last six road day games.

• Probable Starting Pitcher: Ronel Blanco      Record this season: 0-0      ERA: 7.71
• Road Record: 0-0
• Last 5 against White Sox: 0-0

Why the Houston Astros will win

• The Astros have won each of their last four games as underdogs against AL Central opponents.
• The White Sox have lost seven of their last eight day games following a home loss.
• The Astros have covered the run line each of their last seven games against teams that held a winning record.
• The White Sox have failed to cover the run line in each of their last five day games against American League opponents following a home loss.
• The Astros have led after 5 innings in four of their last five day games against American League opponents that held a winning record.
• The Astros have led after 3 innings in five of their last six day games against the White Sox at Rate Field.

Total Runs Facts

• Six of the Astros’ last seven road games against American League opponents have gone OVER the total runs line.
• Four of the last five games between the Astros and White Sox at Rate Field have gone OVER the total runs line.
• There has been at least one run scored in the first inning in each of Erick Fedde’s last six appearances as a starter.
• There has been no run scored during the first inning in each of the Astros’ last six day games.

Chicago White Sox Player Prop Facts

• Erick Fedde has recorded a win in four of his last five appearances in day games.
• Braden Montgomery has recorded at least one hit in each of the White Sox’s last six games against opponents that held a losing record.
• Randal Grichuk has hit a home run in two of his last three appearances in day games against AL West teams that held a losing record.
• Colson Montgomery ranks 10th in the league in Home Runs (24) this season.

Houston Astros Player Prop Facts

• Yordan Alvarez has hit a home run in each of the Astros’ last two day games against AL Central opponents that held a winning record.
• Ronel Blanco has recorded six or more strikeouts in four of his last five appearances.
• Yainer Diaz has recorded at least one hit in each of his nine previous appearances against the White Sox after playing the previous day.
• Yordan Alvarez ranks 1st in the league in Home Runs (34) this season.

Matchup/League Facts

• The White Sox rank 24th in the league for strikeouts against this season (924).
• The White Sox rank 24th in the league for strikeouts against this season (924).
• The Astros rank 30th in the league for walks allowed this season (458).
• The Astros rank 30th in the league for walks allowed this season (458).

Astros vs White Sox Prediction

The Astros are 7-3 in their last 10 meetings against the White Sox and are 3-1 in their last 4 visits in Chicago.

In this Astros vs White Sox Prediction, the White Sox are coming as -115 home favorites. I like the White Sox at home in this one as they are looking to avoid the series sweep. Erick Fedde has been very good at home with a 2.91 ERA, while Ronel Blanco gave up 4 runs in his season debut for the Astros. The White Sox have both a better offense and a better bullpen and I expect them to win this one at home.