Rams vs Bills Prediction 10/12/26 NFL Picks Today

In this article we will formulate a Rams vs Bills prediction for this NFL game on Monday, October 12th at SoFi Stadium in Inglewood, California. Let’s take a look at the prediction for this week 5 matchup.

Los Angeles Rams Betting Preview

The Los Angeles Rams are 2-2 this season after they defeated the Eagles by a score of 24-20 last week. Los Angeles trailed 20-10 at halftime and 20-10 late in the fourth quarter, but they scored 14 points in the last four minutes for the win. The Rams out gained Philadelphia by a total of 415-172, went 7-16 on third downs, and lost the turnover battle by a total of 2-0 in the game. Matthew Stafford threw for 317 yards and two interceptions, while Puka Nacua caught nine passes for 125 yards. Kyren Williams rushed 16 times for 80 yards and two scores in the win. 

Prior to that game, Los Angeles lost to the Broncos by a score of 30-26, but did defeat the Giants by a score of 28-6 before that. The Rams have scored 21.3 points per game with 290.3 passing yards and 126.8 rushing yards per game, while they have allowed 20.8 points against per game this season. Matthew Stafford has thrown for 1,189 yards with six touchdowns and six interceptions this season. 

Buffalo Bills Betting Preview

The Buffalo Bills are 3-1 this year after they lost to the Patriots by a score of 29-26 last week. Buffalo led 17-14 at halftime and 26-21 in the fourth, but they allowed a touchdown with 1:50 left for the loss. The Bills were out gained by a total of 405-340, went 6-12 on third downs, and tied the turnover battle at two in the game. Josh Allen threw for 253 yards, one touchdown, and one interception, while Keon Coleman caught six passes for 116 yards and one score. James Cook III rushed 12 times for 75 yards and one touchdown in the loss. 

Prior to that game, Buffalo defeated the Chargers by a score of 24-16 and the Lions by a score of 41-31. The Bills have scored 31.8 points per game with 247.3 passing yards and 139.0 rushing yards per game, while they have allowed 26.8 points against per game this season. Josh Allen has thrown for 1,039 yards with six touchdowns and three interceptions this year. 

Why the Los Angeles Rams will win

• The Rams have won each of their last six Monday games against teams that held a winning record.
• The Bills have lost each of their last four road games without Dawson Knox.
• The Rams have covered the spread in each of their last six Monday games against teams that held a winning record.
• The Bills have failed to cover the spread in each of their last four road games without Dawson Knox.
• The Rams have scored the first touchdown in nine of their last 10 games as favorites following a win.
• The Rams have won the first half in eight of their last nine October games against AFC opponents.
• The Rams have won the first quarter in five of their last six Monday games against teams that held a winning record.

Why the Buffalo Bills will win

• The Rams have lost each of their last six Week 5 home games.
• The road team has won each of the Rams’ last six Week 5 games.
• The road team has covered the spread in each of the Rams’ last seven Week 5 games.
• The Rams have failed to cover the spread in each of their last six Week 5 home games.
• The Bills have won the first quarter in each of their last four games as underdogs.
• The Bills have scored the first touchdown in four of their last five games as underdogs against NFC West opponents.
• The Rams have lost the first half in each of their last five October games against AFC East opponents.

Total Points Facts

• Nine of the Bills’ last 10 October games as underdogs have gone UNDER the total points line.
• Seven of the Rams’ last eight Monday games have gone UNDER the total points line.

Los Angeles Rams Player Prop Facts

• Kyren Williams has scored the last touchdown in each of his three previous October appearances with the Rams as home favorites.
• Kyren Williams has scored the first touchdown in three of his four previous October appearances against AFC opponents.
• Kyren Williams has scored two touchdowns in three of the Rams’ last four games as favorites against teams that held a winning record.
• Matthew Stafford has recorded 286+ passing yards in each of his last four Monday regular season home appearances.
• Puka Nacua has recorded 98+ receiving yards in each of his six previous home appearances against AFC opponents.
• Blake Corum has recorded 48+ rushing yards in each of the Rams’ last six games played on the West Coast.
• Matthew Stafford has recorded 24+ completions in each of the Rams’ last seven games as favorites with a total points line of at least 50.0.
• Kyren Williams has scored at least one touchdown in seven of his last eight October appearances.
• Blake Corum has recorded 61+ rushing and receiving yards in each of the Rams’ last six games played on the West Coast.
• Heading into Week 5, Matthew Stafford has recorded the equal-most passing touchdowns in a single game this season (4 vs Giants, Week 2).

Buffalo Bills Player Prop Facts

• Josh Allen has scored two touchdowns in each of the Bills’ last five games as underdogs with a total points line of at least 50.0.
• Josh Allen has recorded 253+ passing yards in 17 of the Bills’ last 18 road games with a total points line of at least 50.0.
• James Cook has recorded 95+ rushing and receiving yards in seven of the Bills’ last eight regular season games as underdogs.
• Josh Allen has recorded 38+ rushing yards in seven of the Bills’ last eight games as road underdogs with a total points line of at least 50.0.
• Dawson Knox has recorded 12+ receiving yards in nine of the Bills’ last 10 games following a loss.
• Josh Allen has recorded 22+ completions in each of the Bills’ last seven road games with a total points line of at least 50.0.
• Josh Allen has scored at least one touchdown in each of the Bills’ last six games as underdogs with a total points line of at least 50.0.
• Heading into Week 5, Gregory Rousseau ranks 1st in the NFL in sacks (6.0) this season.

Matchup/League Facts

• Rams – two different players have recorded 70+ rushing yards in a game this season – equal-most in the NFL, heading into Week 5.
• Rams – six different players have recorded 50+ receiving yards in a game this season – most in the NFL, heading into Week 5.
• Bills – four different players have recorded 80+ receiving yards in a game this season – equal-most in the NFL, heading into Week 5.
• Bills – three different players have recorded 90+ receiving yards in a game this season – equal-most in the NFL, heading into Week 5.

Rams vs Bills Prediction 

Buffalo comes into this matchup after picking up their first loss of the season last week and they have allowed 29+ points in three of their four games. The Bills may struggle to get stops, but they have scored at least 26 points in three of their first four games. Los Angeles has been pretty inconsistent this year and they were very lucky to win last week in Philly. The Rams have a ton of talent, but something just seems a little off to start the year. This is a very high number, but I love both offenses and I am taking the over here.