Oklahoma State Cowboys (4-1) vs. Houston Cougars (5-1)
October 17, 2026 7:30 pm EDT
The Line: Houston Cougars -192 / Oklahoma State Cowboys 160; Over/Under: 62.5
(Get latest betting odds)
In this article we will formulate a Houston vs Oklahoma State prediction for this College Football game on Saturday, October 17th at TDECU Stadium in Houston, Texas. Let’s take a look at the prediction for this Week 7 matchup.
Houston Cougars Betting Preview
The Houston Cougars are 5-1 (2-1) this season after they defeated Kansas State by a score of 35-16 in their last game. Houston led 21-3 at halftime and they added 14 points in the third quarter in the win. The Cougars out gained Kansas State by a total of 475-299, went 7-14 on third downs, and won the turnover battle by a total of 1-0 in the game. Conner Weigman threw for 242 yards and four touchdowns, while Patrick Overmyer caught eight passes for 83 yards and four scores. Re’Shaun Sanford II rushed 20 times for 90 yards in the win.
Prior to that game, Houston defeated UCF by a score of 27-17 and Georgia Southern by a score of 42-28. The Cougars have scored 40.0 points per game with 251.8 passing yards and 230.0 rushing yards per game, while they have allowed 19.2 points against per game this season. Conner Weigman has thrown for 1,428 yards with 15 touchdowns and one interception, while Patrick Overmyer has 33 receptions for 400 yards and six scores this season.
Oklahoma State Cowboys Betting Preview
The Oklahoma State Cowboys are 4-1 (2-0) this year after they defeated UCF by a score of 42-28 last week. Oklahoma State was tied 21-21 at halftime, but they scored the first 21 points in the second half to run away with the win. The Cowboys out gained UCF by a total of 414-375, went 4-9 on third downs, and won the turnover battle by a total of 2-1 in the game. Drew Mestemaker threw for 304 yards and two touchdowns, while Justin Bowick caught six passes for 98 yards and one score. Caleb Hawkins rushed 23 times for 83 yards in the win.
Prior to that game, Oklahoma State defeated West Virginia by a score of 41-24 and Murray State by a score of 59-0. The Cowboys have scored 38.2 points per game with 322.4 passing yards and 199.0 rushing yards per game, while they have allowed 21.4 points against per game this season. Drew Mestemaker has thrown for 1,575 yards with 13 touchdowns and five interceptions this year.
Why the Houston Cougars will win
- Houston has won each of its last 13 October games as a favorite.
- Oklahoma State has lost each of its last six games against teams from Texas.
- Oklahoma State has failed to cover the spread in each of its last five October games as an underdog.
- The home team has covered the spread in five of Oklahoma State’s last six games.
- Oklahoma State has lost the first half in eight of its last nine road games.
- Houston has won the first quarter in five of its last six games.
Why the Oklahoma State Cowboys will win
- Oklahoma State has won each of its last four games.
- Houston has lost 17 of its last 20 games against AP-ranked teams.
- Oklahoma State has covered the spread in each of its last six games as an underdog.
- Houston has failed to cover the spread in each of its last four home games against teams from Oklahoma.
- The road team has won the first half in each of Houston’s last four games.
- The underdog has won the first quarter in three of Houston’s last four games.
Total Points Facts
- Nine of Houston’s last 10 games as a favorite have gone OVER the total points line.
- Eight of Oklahoma State’s last 10 games as an underdog against teams from Texas have gone OVER the total points line.
Houston Cougars Player Prop Facts
- Heading into Week 7, Conner Weigman ranks 2nd in the league for TD:INT ratio (15.00) this season.
Oklahoma State Cowboys Player Prop Facts
- Heading into Week 7, Sam Keltner ranks T3rd amongst FBS players for made field goals (12) this season.
Matchup/League Facts
- Houston ranks 1st among FBS teams for 3rd down conversion percentage this season (62.7).
- Houston ranks T3rd among FBS teams for 1st downs this season (162).
- Oklahoma State ranks 6th among FBS teams for yards per game this season (521.4).
- Oklahoma State ranks 6th among FBS teams for passing yards per game this season (322.4).
Houston vs Oklahoma State Prediction
Oklahoma State comes into this matchup on a four game winning streak and they have scored 39+ points in all four wins. The Cowboys lost their first game of the year to Tulsa, but they have dominated since then. Houston has won three in a row and they have scored 27+ in all three. The Cougars have a road loss to Texas Tech, but Weigman is a solid quarterback. I think this is a game that could go either way, so I will gladly take the points with Oklahoma State here.
