Best MLB Prop Bets Today 9/22/21

It’s a full slate of games across the MLB and there are plenty of MLB prop bets across the league. Let’s take a look at the best MLB prop bets to make your Wednesday a winning one. 

Keegan Akin under 3.5 strikeouts (-125)

Keegan Akin isn’t a strikeout pitcher, and he isn’t going to run up that number against the Philadelphia Phillies. Two starts ago Akin had three strikeouts and in his last start, he went four innings but had zero strikeouts. Akin will finish with only one or two strikeouts. 

Philadelphia Phillies over 5.5 runs (+110)

The Philadelphia Phillies are going to have no issue running up the score against Akin. In two of Akin’s last three starts he has given up four runs, and in the other game he gave up three runs. The Phillies bats have been a bit cold heading into this game, but going against Akin is the perfect way to break out of that. 

San Francisco Giants over 4.5 runs (-125)

The San Francisco Giants are going to be hitting 1-9 in this game against Vince Velasquez. The San Diego Padres are desperate for pitching, but Vince Velasquez isn’t the answer for them. Over Velasquez’s last start he went six innings giving up nine runs. The Giants will finish with at least seven runs. 

Chicago Cubs under 3.5 runs (-125)

The Chicago Cubs are going to struggle to score in this game. Joe Ryan is on the mound and he has been lights out this year. Over Ryan’s last two starts he has gone 12 innings total giving up only one run. The Cubs are going to struggle against him, and finish under 3.5 runs.

Shane Mickle's Free Pick:
Up to $5000 Risk Free Bet; Use code DAWGZRF

Shane Mickle

I have been following sports for as long as I can remember and started writing about them back in high school. My favorite sports include MLB, NBA, NFL, CFB, CBB, and the UFC. Follow me on Twitter at @shanemickle

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