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St. Louis Cardinals vs Milwaukee Brewers MLB Picks, Odds, Predictions 9/29/21

Milwaukee Brewers (94-63) vs. St. Louis Cardinals (88-69)
September 29, 2021 7:45 pm EDT
The Line: St. Louis Cardinals -132 / Milwaukee Brewers +100; Over/Under: -7.5
(Get latest betting odds)

The Milwaukee Brewers and St. Louis Cardinals meet Wednesday in MLB action at Busch Stadium. The Brewers need a win after losing six of their last nine games. The Cardinals look to build on their 17-game winning streak.

The Milwaukee Brewers have scored 12 runs in their last three games and four or more runs in five of their last 10 games. The Brewers have won 10 of their last 12 games when scoring four or more runs. Avisail Garcia leads the Brewers with 119 hits and 85 RBI while Kolten Wong and Luis Urias have combined for 235 hits and 120 RBI. Adrian Houser gets the ball, and he is 9-6 with a 3.34 ERA and 104 strikeouts this season. Houser is 3-2 with a 2.61 ERA and 29 strikeouts in his career against the Cardinals.

The St. Louis Cardinals have scored 18 runs in their last three games and four or more runs in seven straight games. The Cardinals have won 15 straight games when scoring four or more runs. Paul Goldschmidt leads the Cardinals with 175 hits and 98 RBI while Tommy Edman and Nolan Arenado have combined for 314 hits and 159 RBI. Miles Mikolas gets the ball, and he is 2-2 with a 4.15 ERA and 24 strikeouts this season. Mikolas is 5-1 with a 3.83 ERA and 39 strikeouts in his career against the Brewers.

The Brewers are 11-3 in their last 14 during game 2 of a series and 38-15 in their last 53 road games. The Cardinals are 5-0 in their last 5 during game 2 of a series and 35-17 in their last 52 overall. The under is 8-3-1 in Brewers last 12 road games. The over is 5-1 in Cardinals last 6 overall. The Brewers are 4-1 in the last 5 meetings in St. Louis.

The Brewers have the pitching edge here and Houser has been dominant this month, allowing 16 hits and five earned runs in his last 25 innings. The Cardinals also clinched a wild card spot last night, so they may be a little hungover or in a letdown spot. With that said, are you really going to bet against a team that’s won 17 straight games? The Cardinals are five wins away from tying the 2017 Indians for the longest winning streak since the expansion era in 1961. I’m riding the hot hand until it runs cold.

Randy Chambers's Free Pick: St. Louis Cardinals -132

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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