
Brewers vs Cardinals Prediction 6/15/25 MLB Picks Today
St. Louis Cardinals (37-34) vs. Milwaukee Brewers (38-34)
June 15, 2025 2:10 pm EDT
The Line: Milwaukee Brewers -126 / St. Louis Cardinals 104; Over/Under: 8
(Get latest betting odds)
In this article, we will formulate a Brewers vs Cardinals prediction for this MLB game on Sunday, June 15, at American Family Field in Milwaukee, Wisconsin. Let’s take a look at the prediction for this MLB matchup.
St. Louis Cardinals Betting Preview
The St. Louis Cardinals (37-34, 15-20 Away) went through their worst part of the season, during which they lost six games in a row, but avoided the seventh thanks to an 8-5 win over the Brewers on Saturday. The Cards lost the opening two games of this series and were swept by the Blue Jays before that. In Saturday’s victory, Nolan Gorman led the offense with three RBI, while Andre Pallante pitched for 4.1 innings in a no-decision, allowing four runs (three earned) on four hits with seven strikeouts and two walks. Kyle Leahy was credited with the win.
This year, the Cardinals average 4.59 runs per game (10th in the MLB) on a .255/.326/.391 triple-slash. When it comes to pitching, the Cardinals’ staff has a 4.00 ERA (18th) and 1.28 WHIP (16th). Willson Contreras leads the Cardinals with a .255 batting average, nine home runs, and 44 RBI this season.
The projected starting pitcher for the Cardinals is Miles Mikolas, who is 4-3 in 13 starts this season, with a 4.48 ERA and 1.31 WHIP in 66.1 innings.
Milwaukee Brewers Betting Preview
The Milwaukee Brewers (38-34, 22-15 Home) lost back-to-back series at home to the San Diego Padres and Atlanta Braves, but will not suffer the third sweep in a row thanks to wins over the Cardinals in the opening two games of the current series. Still, the Brewers lost Game 3 on Saturday, 8-5. Sal Frelick led the team with two RBI, while Jose Quintana took the loss after allowing seven runs (five earned) on eight hits with four strikeouts and three walks in 4.1 innings.
This season, the Brewers’ average 4.35 runs per game (13th in the MLB) on a .236/.313/.363 triple-slash. When it comes to pitching, the Brewers’ staff has a 3.81 ERA (13th) and 1.30 WHIP (18th). Christian Yelich leads the Brewers with a .231 batting average, 13 home runs, and 42 RBI this season.
Quinn Priester will take the mound for the Brewers on Sunday. The 24-year-old right-hander has a 4-2 record in eight starts this year with a 3.65 ERA and 1.30 WHIP in 61.2 innings.
Why the Brewers will beat the Cardinals
- The Brewers have won 10 of their last 11 day games against NL Central opponents following a home loss.
- The Cardinals have lost each of their last five day games against NL Central opponents following a road win.
- The Cardinals have failed to cover the run line in 13 of their last 15 day games against NL Central opponents following a road win.
- The Brewers have covered the run line in each of their last four games against the Cardinals following a loss.
Total Runs Facts
- Four of the Brewers’ last five games as favorites have gone UNDER the total runs line.
- Six of the Cardinals’ last eight road games against National League opponents have gone UNDER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the Brewers’ last 11 games at American Family Field.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Cardinals’ last four day games at American Family Field.
Matchup/League Facts
- The Brewers rank T27th in the league for walks allowed this season (260).
- The Brewers rank 24th in the league for home runs this season (64).
- The Cardinals rank T3rd in the league for home runs allowed this season (58).
- The Cardinals rank 4th in the league for doubles this season (124).
Brewers vs Cardinals Prediction
The Cardinals won six of the previous ten H2H encounters, while this season, each team recorded three wins in six meetings. I am going with the Brewers in this one because I prefer Priester over Mikolas. Priester allowed more than two runs just once in his last seven starts, and opened June with just two runs in two games (11.0 innings). Miles Mikolas, on the other hand, surrendered 3+ runs in his previous three starts, and 13 in total, so I am backing Milwaukee to get to him early on. Go with the Brewers.