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Brewers vs Mariners Prediction 7/22/25 MLB Picks Today

Brewers vs Mariners
July 22, 2025 9:40 pm EDT
The Line: Brewers +105 / Mariners -125 / Over/Under: 7
(Get latest betting odds)

The Milwaukee Brewers are visiting the Seattle Mariners on Tuesday, July 22nd at the T-Mobile Park in the second game of this series, with the Brewers having a 1-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Brewers vs Mariners Prediction. We will examine:

The Seattle Mariners’ recent form and player performance


The Milwaukee Brewers’ recent form and player performance

Recent betting trends and streaks involving the Seattle Mariners

Recent betting trends and streaks involving the Milwaukee Brewers

Recent betting trends in games played between the Milwaukee Brewers vs Seattle Mariners

A summary that ties it all together and produces a favorable betting outcome for the Milwaukee Brewers vs Seattle Mariners game

Seattle Mariners Preview

The Seattle Mariners have a 53-47 record this season and are sitting in second place in the AL West. The Mariners have a 27-23 home record and are 56-39 in over/under. They are coming off a 0-6 home defeat to the Brewers, and have back-to-back losses. Over is 8-1 in their last 9 games, and they are playing the Athletics and the Angels next.

The Mariners have a .249 batting average this season, a .325 OBP, and a .413 Slugging percentage. Seattle’s pitching staff has a 3.94 ERA and 1.27 WHIP. J.P. Crawford leads the Mariners in hits with 103, and is the team’s best hitter with a .285 batting average. Cal Raleigh leads the team both in RBI with 83 and in home runs with 38.

Logan Gilbert (R) is the projected starting pitcher for the Mariners, and he has a 2-3 record, 3.39 ERA, and 1.05 WHIP.

Milwaukee Brewers Preview

The Milwaukee Brewers have a 60-40 record this season and are sitting in first place in the NL Central. They have a 27-23 road record and are 42-55 in over/under. They are coming off a 6-0 road victory over the Mariners, and have 11 consecutive wins. Over is 5-2 in their last 7 games, and they are playing the Marlins and the Cubs next.

The Brewers have a .250 batting average this season, a .325 OBP, and a .385 Slugging percentage. Milwaukee’s pitching staff has a 3.62 ERA and 1.24 WHIP. Jackson Churio leads the Brewers with 112 hits, while Christian Yelich leads the team in RBI, with 66, adding a team-high 19 home runs. Sal Frelick is the team’s best hitter with a .294 batting average.

Jacob Misiorowski (R) is the projected starting pitcher for the Brewers, and he has a 4-1 record, 2.81 ERA, and 0.90 WHIP.

Why the Seattle Mariners will win

  • The Mariners have won six of their last seven games against NL Central opponents following a loss.
  • The Brewers have lost four of their last five night games against American League opponents that held a winning record.
  • The Mariners have covered the run line in six of their last seven games against NL Central opponents following a loss.
  • The Brewers have failed to cover the run line in four of their last five night games against American League opponents that held a winning record.
  • The Brewers have trailed after 3 innings in three of their last four night games against American League opponents that held a winning record.
  • The Brewers have lost the first inning in three of their last four night games against American League opponents that held a winning record.
  • The Mariners have led after 5 innings in four of their last five night games against opponents that held a winning record.

Why the Milwaukee Brewers will win

  • The Brewers have won each of their last 11 games as underdogs following a win.
  • The Mariners have lost each of their last three games as favorites against the Brewers following a home loss.
  • The Brewers have covered the run line in each of their last 15 games as underdogs.
  • The Mariners have failed to cover the run line in each of their last six night games against National League opponents.
  • The Brewers have led after 3 innings in six of their last seven games against AL West opponents that held a winning record.
  • The Brewers have led after 5 innings in five of their last six night games.

Total Runs Facts

  • Each of the Mariners’ last six home games against NL Central opponents have gone UNDER the total runs line.
  • Each of the Brewers’ last four night games against AL West opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Brewers’ last eight games.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Mariners’ last six home games.

Matchup/League Facts

  • The Mariners rank 28th in the league for doubles this season (142).
  • The Mariners rank 28th in the league for triples this season (5).
  • The Brewers rank 2nd in the league for steals this season (116).
  • The Brewers rank 27th in the league for doubles this season (144).

Brewers vs Mariners Prediction

The Brewers are 7-1 in their 8 meetings against the Mariners, and have won their last five meetings in Seattle.

In this Brewers vs Mariners Prediction, the Mariners are coming as -125 home favorites. The wrong team is favored once again, as the Brewers have a better record than the Mariners, while both teams have exactly 27 home/away wins. We get the hottest team in the league with the better pitcher on the mound as an underdog. Give me the Milwaukee Brewers as a road dog in this one.

Nikos Lagouretos's Free Pick: Milwaukee Brewers +105

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