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Brewers vs Pirates Prediction 6/25/25 MLB Picks Today

Pittsburgh Pirates (32-49) vs. Milwaukee Brewers (44-36)
June 25, 2025 2:10 pm EDT
The Line: Milwaukee Brewers -103 / Pittsburgh Pirates -117; Over/Under: 6.5
(Get latest betting odds)

In this article we will formulate a Brewers vs Pirates prediction for this MLB game on Wednesday, June 25th at American Family Field in Milwaukee, Wisconsin. Let’s take a look at the prediction for this MLB matchup. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 44-36 this season after they split the first two games in this series by scores of 4-5 and 9-3. In their game two win, Milwaukee led 7-0 in the fifth inning, which was more than enough in the blowout win. The Brewers recorded 11 hits in the game and they were led by Ortiz, who went 2-4 with two home runs and four RBIs in the win. Milwaukee started Peralta, who allowed seven hits and three earned runs over 5.0 innings for the win, while four relievers combined for four scoreless innings. 

Prior to this series, the Brewers swept the Twins in three games and split two games with the Cubs. Milwaukee has won five of their last six games and they are currently second in the NL Central standings. The Milwaukee pitching staff has a 3.86 ERA with a 1.30 WHIP and a .241 opponent batting average, while the offense has scored 375 runs with a .247 batting average and a .322 on base percentage this season. Christian Yelich has led Milwaukee with 15 home runs and 56 RBIs, while Jackson Chourio has added 12 home runs and 46 RBIs this year. The projected starting pitcher for Milwaukee is Jacob Misiorowski, who is 2-0 with a 1.64 ERA and a 0.55 WHIP over 11.0 innings pitched this season. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 32-49 this year after they lost game two by a score of 9-3 on Tuesday. Pittsburgh cut the deficit to 7-3 in the sixth inning, but they couldn’t get any closer in the loss. The Pirates recorded eight hits and they committed one error in the game, while they were led by Gonzales, who went 1-4 with one home run and three RBIs in the loss. Pittsburgh started Heaney, who allowed seven hits and seven earned runs over 4.0 innings for the loss, while three relievers combined for four scoreless innings. 

Prior to this series, the Pirates lost two out of three against the Rangers and two out of three against the Tigers. Pittsburgh has lost three of their last five games and they are currently last in the NL Central standings. The Pittsburgh pitching staff has a 3.86 ERA with a 1.21 WHIP and a .234 opponent batting average, while their offense has scored 265 runs with a .229 batting average and a .303 on base percentage this season. Oneil Cruz has led Pittsburgh with 13 home runs and 31 RBIs, while Bryan Reynolds has added eight home runs and 39 RBIs this year. The projected starting pitcher for Pittsburgh is Paul Skenes, who is 4-6 with a 1.85 ERA and a 0.88 WHIP over 102.0 innings pitched this year. 

Why the Brewers will beat the Pirates

  • The Brewers have won each of their last four games as underdogs.
  • The Pirates have lost five of their last six games as road favorites against National League opponents.
  • The Pirates have failed to cover the run line in each of their last six games as road favorites against National League opponents.
  • The Brewers have covered the run line in 11 of their last 12 games as underdogs against the Pirates following a home win.
  • The Brewers have led after 3 innings in each of their last six games as underdogs against NL Central opponents.
  • The Brewers have led after 5 innings in each of their last four day games.

Why the Pirates will beat the Brewers

  • The Brewers have lost seven of their last eight games against National League opponents following a win.
  • The road team has won five of the Brewers’ last six games.
  • The Brewers have failed to cover the run line in each of their last 11 home games against National League opponents following a win.
  • The Pirates have covered the run line in each of their last six games against National League opponents following a loss.
  • The Pirates have led after 5 innings in each of their last six Wednesday games as favorites.

Total Runs Facts

  • Each of the Pirates’ last six day games against National League opponents have gone UNDER the total runs line.
  • Five of the Brewers’ last six games have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Pirates’ last 12 games as favorites.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last 10 day games between the Pirates and Brewers at American Family Field.

Milwaukee Brewers Player Prop Facts

  • Jackson Chourio has hit a home run in two of the Brewers’ last three games as home underdogs.
  • Christian Yelich has recorded at least one hit in each of his last 18 appearances against NL opponents that held a losing record.
  • Andrew Vaughn has recorded a Double in each of his three previous appearances at American Family Field.

Pittsburgh Pirates Player Prop Facts

  • Bryan Reynolds has recorded a Double in each of the Pirates’ last three games.
  • Bryan Reynolds has hit a home run in four of the Pirates’ last eight games as favorites against NL Central opponents.
  • Andrew McCutchen has recorded at least one hit in each of his last 11 appearances with the Pirates as road favorites against the Brewers.

Brewers vs Pirates Prediction 

Milwaukee comes into this contest playing some very solid baseball over the last week and they are closing in on the Cubs in the NL Central. The Brewers are 24-16 at home this year, while the Pirates are 12-28 on the road. Pittsburgh has the second lowest scoring offense in the MLB and they will go against Misiorowski, who has been elite through two starts. Pittsburgh is starting Skenes, who has allowed a total of three earned runs in his last five starts. I know this is a low total, but I like the under here. 

David Racey's Free Pick: Under 6.5

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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