Chicago Cubs (46-32) vs. St. Louis Cardinals (43-36)
June 24, 2025 7:45 pm EDT
The Line: St. Louis Cardinals -101 / Chicago Cubs -120; Over/Under: 9
(Get latest betting odds)
In this article, we will formulate a Cardinals vs Cubs prediction for this MLB game on Tuesday, June 24, at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup.
Chicago Cubs Betting Preview
The Chicago Cubs (46-32, 21-17 Away) lost four of the previous five games, which is their weakest run of results this season. The Cubs lost the latest series to the Seattle Mariners and opened the current series against the St. Louis Cardinals with an 8-2 defeat on Monday. Ben Brown took the loss after allowing eight runs on nine hits with three strikeouts and two walks in 5.0 innings.
This season, the Cubs average 5.37 runs per game (2nd in the MLB) on a .254/.324/.442 triple-slash. When it comes to pitching, the Cubs’ staff has a 3.89 ERA (16th) and 1.26 WHIP (14th). Seiya Suzuki leads the Cubs with a .256 batting average, 20 home runs, and 64 RBI this season.
Jameson Taillon will take the mound for the Cubs on Tuesday. The 33-year-old right-hander has a 7-4 record in 15 starts this year with a 3.84 ERA and 1.04 WHIP in 86.2 innings.
St. Louis Cardinals Betting Preview
The St. Louis Cardinals (43-36, 25-15 Home) were on a five-game winning streak after sweeping the Chicago White Sox and beating the Cincinnati Reds in two games before losing Game 3 of that series against Cincy. Still, the Cards returned to winning ways with an 8-2 victory over the Chicago Cubs last night. Brendan Donovan, Alec Burleson, Lars Nootbaar, and Nolan Gorman led the offense with two RBI apiece. Matthew Liberatore got the win after allowing two runs on six hits with five strikeouts and one walk across 7.0 innings of work.
This year, the Cardinals average 4.73 runs per game (8th in the MLB) on a .255/.327/.396 triple-slash. When it comes to pitching, the Cardinals’ staff has a 3.90 ERA (17th) and 1.25 WHIP (13th). Willson Contreras leads the Cardinals with a .248 batting average, ten home runs, and 50 RBI this season.
The projected starting pitcher for the Cardinals is Michael McGreevy, who is 1-1 in two starts this season, with a 2.70 ERA and 0.84 WHIP in 16.2 innings.
Total Runs Facts
- Each of the Cubs’ last four road games against NL Central opponents have gone OVER the total runs line.
- Each of the last four games between the Cubs and Cardinals at Busch Stadium have gone OVER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Cardinals’ last eight night games against National League opponents.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Cubs’ last four night games against National League opponents.
Matchup/League Facts
- The Cardinals rank 28th in the league for strikeouts this season (574).
- The Cardinals rank 3rd in the league for home runs allowed this season (64).
- The Cubs rank 3rd in the league for doubles this season (139).
- The Cubs rank T3rd in the league for triples this season (15).
Cardinals vs Cubs Prediction
The teams have traded victories in the past couple of years, each recording five in the previous ten H2H encounters, while the Cubs won four of the last six. Seven of the last eight duels went Over, and I am going with another Over in this one. Both teams are bettor-friendly when it comes to Over bets; St. Louis is 42-34 Over/Under, while Chicago is 39-31 Over/Under. I am not sure about Jameson Taillon and Michael McGreevy, today’s starters, so I am backing Over.
