MLB Picks

Cardinals vs Dodgers Prediction 6/6/25 MLB Picks Today

LA Dodgers (38-25) vs. St. Louis Cardinals (34-28)
June 6, 2025 8:15 pm EDT
The Line: St. Louis Cardinals -105 / LA Dodgers -115; Over/Under: 8.5
(Get latest betting odds)

The Los Angeles Dodgers and the St. Louis Cardinals meet Friday in MLB action from Busch Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Dodgers vs. St. Louis Cardinals prediction.

Starting Pitching Matchup

The Los Angeles Dodgers will send out Justin Wrobleski for the start here, and Wrobleski is 1-1 with an 8.00 ERA and 8 strikeouts this season. This will be Wrobleski’s second career start against the Cardinals. Sonny Gray will get the start for the Cardinals here and is 6-1 with a 3.65 ERA and 76 strikeouts this season. In his last five starts against the Dodgers, Gray is 0-3 with a 4.26 ERA and 31 strikeouts.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to build off their 6-5 win over the New York Mets last time out to improve to 38-25 on the year. After this series, the Dodgers will head on the road for a series against the rival San Diego Padres.

Dodgers Salvage Series Split Vs. Mets

Shohei Ohtani has 72 hits, including 9 doubles, 23 home runs, 39 RBIs, and 4 triples, while Tommy Edman has 40 hits with 9 home runs and 29 RBIs. Michael Conforto has 29 hits with 9 doubles, while Teoscar Hernandez has 52 hits with 10 home runs, 14 doubles, and 43 RBIs as well this season. Ohtani has a team-high 11 stolen bases, while Max Muncy has 8 doubles but also has 55 strikeouts so far this season. Mookie Betts has also chipped in 9 home runs and 35 RBIs on the year. Freddie Freeman has also logged 69 hits with a team-high 19 doubles, 9 home runs, and 40 RBIs.

Why the Los Angeles Dodgers will win

  • The Dodgers have won nine of their last 10 games against National League opponents following a home win.
  • The Cardinals have lost three of their last four games.
  • The Cardinals have failed to cover the run line in each of their last five games at Busch Stadium.
  • The road team has covered the run line in each of the Dodgers’ last five games.

Los Angeles Dodgers Player Prop Facts

  • Andy Pages has hit a home run in three of his four previous road appearances against NL Central opponents that held a winning record.
  • Andy Pages has recorded an RBI in each of the Dodgers’ last six games as road favorites.
  • Mookie Betts has scored at least one run in eight of the Dodgers’ last nine games as road favorites against NL opponents.
  • Teoscar Hernandez has recorded a Double in each of his last four road appearances against NL opponents.
  • Miguel Rojas has recorded at least one hit in each of his last 16 appearances against the Cardinals after playing the previous day.
  • Freddie Freeman has recorded at least one Single in each of the Dodgers’ last 10 games as road favorites.
  • Shohei Ohtani ranks 2nd in the league in Home Runs (23) this season.

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to bounce back from a 7-5 loss at the hands of the Kansas City Royals last time out to sit at 34-28 on the year. After this series, the Cardinals will square off in a home series against the Toronto Blue Jays.

Cardinals Drop Another Series

Brendan Donovan has a team-high 72 hits along with 19 doubles, 4 home runs, and 24 RBIs, while Lars Nootbaar has 59 hits with 8 home runs, 28 RBIs, 12 doubles, and 4 stolen bases. Nolan Arenado also has 50 hits with 10 doubles, 7 home runs, and 31 RBIs of his own, and Victor Scott II has 45 hits with 8 doubles, a triple, 19 RBIs, and a team-high 17 stolen bases. Willson Contreras has also chipped in 55 hits with 6 home runs and 36 RBIs of his own this season.

Why the St. Louis Cardinals will win

  • The Cardinals have won each of their last seven games as home underdogs following a home loss.
  • The Dodgers have lost six of their last seven games as road favorites against National League opponents following a win.
  • The Cardinals have covered the run line in each of their last eight games as underdogs against National League opponents.
  • The Dodgers have failed to cover the run line in each of their last seven games as road favorites against National League opponents following a win.

St. Louis Cardinals Player Prop Facts

  • Masyn Winn has hit a home run in each of the Cardinals’ last two games as underdogs against the Dodgers.
  • Sonny Gray has recorded a win in three of his last four appearances with the Cardinals as home underdogs.
  • Willson Contreras has recorded at least one RBI in each of his last six home appearances against NL opponents that held a winning record.
  • Masyn Winn has scored at least one run in 11 of his last 12 appearances against NL West opponents.
  • Sonny Gray has recorded six or more strikeouts in 10 of his last 11 home appearances against opponents that held a winning record.
  • Willson Contreras has recorded at least one hit in each of his last 12 home appearances against opponents that held a winning record.
  • Willson Contreras has recorded a Double in four of the Cardinals’ last five games.
  • Masyn Winn has recorded at least one Single in each of the Cardinals’ last six games against NL West opponents that held a winning record.
  • Sonny Gray ranks T6th in the league for Wins (6) this season.

Total Runs Facts

  • Seven of the Cardinals’ last eight games have gone OVER the total runs line.
  • Eight of the Dodgers’ last 10 games have gone OVER the total runs line.

Los Angeles Dodgers vs. St. Louis Cardinals Prediction

I’m on the Cardinals here. I just haven’t loved what I’ve seen in limited action from Wrobleski as he fills in for a Dodger pitching rotation that’s being held together by duct tape at the moment. This feels like the best chance the Cardinals have at a win in this series with Sonny Gray pitching, and the Cardinals have still been a solid home team despite their inconsistencies at times as of late. Give me the Cardinals in this one.

Chris Ruffolo's Free Pick: St. Louis Cardinals -105

Need More? Get Premium Picks

Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

Related Articles

Back to top button