Cubs vs Nationals Prediction 9/6/25 MLB Picks Today

The Chicago Cubs and Washington Nationals meet on Saturday in MLB action from Wrigley Field. Here’s a Cubs vs Nationals prediction. We will look at this from a betting perspective and determine the best Nationals vs Cubs pick.

Cubs Bats Were Alive

The wind was blowing out on Friday afternoon at Wrigley Field, and the Cubs take advantage. They ended up hitting out four home runs and the offense managed 11 runs. Dansby Swanson hit a home run and drove in three RBIs. Ian Happ also walked three times and hit a home run. Javier Assad didn’t have his best start of the season, but he was good enough with some run support. He finished the game going 5.1 innings, giving up three hits and four runs. The Cubs also ended up using four different bullpen members to lock down the game. 

The Cubs are averaging 4.91 runs while their pitching is giving up 4.09 runs per game. The offense is ranked 6th, while the pitching is ranked 7th. Matthew Boyd will be on the mound for the Cubs and he sits with a 12-7 record and an ERA of 2.94. Against the Rockies in his start, he went six innings, giving up six hits and four runs. 

Why the Cubs Will Win

• The Nationals have lost each of their last eight day games against NL Central opponents that held a winning record.
• The home team has won each of the Nationals’ last four games.
• The Nationals have failed to cover the run line in seven of their last eight day games against NL Central opponents.
• The home team has covered the run line in each of the Nationals’ last four games.
• The Cubs have led after 5 innings in five of their last six games against the Nationals at Wrigley Field.
• The Cubs have won the first inning in three of their last four games as favorites against the Nationals at Wrigley Field.
• The Cubs have led after 3 innings in four of their last five day games against the Nationals.

Nationals Pitching Let Them Down

It’s really hard to win a game when you are down 5-0 after the first inning, and that’s exactly the hole that Washington found itself in on Friday afternoon. The bats did show some signs of life but by the time they got the bats going, it was too little too late. Jake Irvin got the start and he went 3.1 innings, giving up five hits and seven runs. Luis Garcia Jr was the top offensive player and he hit a home run and drove in three RBIs. 

The Nationals are averaging 4.24 runs while their pitching is giving up 5.49 runs per game. The offense is ranked 22nd while the pitching is ranked 29th. Brad Lord is going to get the start for the Nationals and he sits with a 12-7 record and an ERA of 2.94. Against the Tampa Bay Rays in his last start he went three innings giving up five hits and seven runs. Two starts ago against the Yankees, he gave up seven runs and eight hits. 

Why the Nationals Will Beat the Cubs

• The Nationals have won seven of their last eight Saturday day games as road underdogs against NL Central opponents.
• The Cubs have lost 10 of their last 13 games as favorites against National League opponents following a win.
• The Cubs have failed to cover the run line in each of their last 11 day games following a win.
• The Nationals have covered the run line in each of their last eight Saturday road games against NL Central opponents.

Cubs vs Nationals Prediction

This game is going to get ugly early, much like it did on Friday for the Nationals. The starting pitching was an issue then, and it’s going to be much of the same here. Brad Lord in his last start gave up seven runs, and he’s going to give up at least that here. The Cubs are averaging 4.91 runs per game, but they have continued to beat up on bad pitchers as of late. The Nationals offense might score a few runs, but it’s not going to be enough for them to have any real shot in this game. Back the Cubs on the run line.