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Diamondbacks vs Brewers Prediction 8/27/25 MLB Picks Today

Diamondbacks vs Brewers
August 27, 2025 7:40 pm EDT
The Line: Brewers -140 / Over/Under 8.5
(Get latest betting odds)

In this article, we will formulate a Diamondbacks vs Brewers Prediction for this MLB game on Wednesday, August 27th at the American Family Field in the third game of this series, with the Brewers having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

Milwaukee Brewers Preview

The Milwaukee Brewers have an 83-50 record this season and are sitting on the first place of the NL Central. They have a 45-22 home record and are 63-66 in over/under. They are coming off a 9-8 home victory over the Dbacks, and have back-to-back wins. Over is 3-1 in their last 4 games and are playing the Blue Jays and the Phillies next.

The Brewers have a .258 batting average this season, .332 OBP and .406 Slugging percentage. Milwaukee’s pitching staff has a 3.62 ERA and 1.23 WHIP. Brice Turang leads the Brewers with 136 hits, while Christian Yelich leads the team in RBI, with 90, adding a team-high 26 home runs. Sal Frelick is the team’s best hitter with a .297 batting average.

Quinn Priester (R) is the projected starting pitcher for the Brewers, and he has a 11-2 record, 3.44 ERA and 1.26 WHIP.

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 64-69 record this season and are sitting on the third place of the NL West. The Diamondbacks have a 30-37 road record and are 64-61 in over/under They are coming off an 8-9 road defeat by the Brewers, and have three consecutive losses. Over is 4-1 in their last 5 games and are playing the Rangers and the Dodgers next.

The Diamondbacks have a .251 batting average this season, .324 OBP and .439 slugging percentage. Arizona’s pitching staff has a 4.58 ERA and 1.33 WHIP. Geraldo Perdomo leads the Diamondbacks with 141 hits, adding a team-high 86 RBI. Ketel Marte is the team’s best hitter with a .290 batting average. Corbin Carroll leads the team in home runs with 27.

Ryne Nelson (R) is the projected starting pitcher for the Diamondbacks, and he has a 6-3 record, 3.63 ERA and 1.07 WHIP.

Why the Milwaukee Brewers will win

  • The Brewers have won 18 of their last 19 night games against National League opponents following a win.
  • The Diamondbacks have lost each of their last seven night games against the Brewers following a road loss.
  • The Diamondbacks have failed to cover the run line in seven of their last eight road games against NL Central opponents.
  • The Brewers have covered the run line in 10 of their last 12 night games following a home win.
  • The Brewers have led after 5 innings in 13 of their last 14 games against National League opponents that held a losing record.
  • The Diamondbacks have trailed after 3 innings in each of their last four road games against NL Central opponents.

Why the Arizona Diamondbacks will win

  • The Diamondbacks have won each of their last nine Wednesday night games as underdogs against NL Central opponents.
  • The Brewers have lost four of their last five games as favorites against the Diamondbacks following a home win.
  • The Diamondbacks have covered the run line in each of their last 10 Wednesday night games as underdogs against NL Central opponents.
  • The Brewers have failed to cover the run line in each of their last seven games as favorites against the Diamondbacks following a win.
  • The Diamondbacks have won the first inning in eight of their last 10 games against National League opponents that held a winning record.
  • The Diamondbacks have led after 5 innings in nine of their last 11 games against National League opponents that held a winning record.
  • The Diamondbacks have led after 3 innings in 10 of their last 13 games against National League opponents that held a winning record.

Total Runs Facts

  • Each of the Diamondbacks’ last five night games against National League opponents have gone OVER the total runs line.
  • Four of the Brewers’ last five night games after playing the previous day have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in 11 of the Diamondbacks’ last 12 night games against National League opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the last five games between the Diamondbacks and Brewers at American Family Field.

Matchup/League Facts

  • The Brewers rank 2nd in the league for runs scored this season (682).
  • The Brewers rank 2nd in the league for hits this season (1164).
  • The Diamondbacks rank 1st in the league for triples this season (33).
  • The Diamondbacks rank 3rd in the league for RBIs this season (643).

Diamondbacks vs Brewers Prediction

The Brewers are 4-2 in their last 6 meetings against the Diamondbacks, and have won their last three meetings in Milwaukee. Over is 4-1 in their last 5 meetings in Milwaukee.

In this Diamondbacks vs Brewers Prediction, the Brewers are coming as -160 home favorites. Nelson has been weaker on the road for the Dbacks, despite his good overall numbers. He has a 5.01 road ERA across 9 road starts, and he has been struggling lately, with a 1-4 record and 12 earned runs in 17.2 innings pitched across his last three starts. On the flip side, Priester has been a winning machine for the Brewers, as he has won his last 9 starts. The Brewers have both a better bullpen and a better offense, and I expect them to dominate this game and get away with another home victory on their way to the top of the NL Central.

Nikos Lagouretos's Free Pick: Milwaukee Brewers -140

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