
Guardians vs Reds Prediction 6/11/25 MLB Picks Today
Cincinnati Reds (35-33) vs. Cleveland Guardians (34-32)
June 11, 2025 1:10 pm EDT
The Line: Cleveland Guardians -115 / Cincinnati Reds -106; Over/Under: 8.5
(Get latest betting odds)
The Cincinnati Reds and Cleveland Guardians meet Wednesday in MLB action at Progressive Field. Here’s a Guardians vs Reds Prediction. This article will include a Guardians vs Reds Pick.
Cincinnati Reds Betting Preview
The Cincinnati Reds are 35-33 on the year and play the Tigers, Twins, and Cardinals next. The Cincinnati Reds are batting .246 on the season, have a .321 OBP, and a .398 slugging percentage. The Cincinnati Reds pitching staff has a 3.66 ERA and a 1.18 WHIP. TJ Friedl leads the Cincinnati Reds with 72 hits and 24 RBI, while Elly De La Cruz and Gavin Lux have combined for 122 hits and 70 RBI.
Nick Lodolo gets the ball for the Cincinnati Reds, and he is 4-4 with a 3.21 ERA and 64 strikeouts this season. Lodolo is 1-1 with a 6.30 ERA and 10 strikeouts in his career against the Cleveland Guardians.
Cleveland Guardians Betting Preview
The Cleveland Guardians are 34-32 on the year and play the Mariners, Giants, and Athletics next. The Cleveland Guardians are batting .232 on the season, have a .305 OBP, and a .373 slugging percentage. The Cleveland Guardians’ pitching staff has a 3.92 ERA and a 1.37 WHIP. Jose Ramirez leads the Cleveland Guardians with 80 hits and 32 RBI, while Steven Kwan and Carlos Santana have combined for 130 hits and 52 RBI.
Logan Allen gets the ball for the Cleveland Guardians, and he is 3-4 with a 4.42 ERA and 40 strikeouts this season. This will be Allen’s second career game against the Cincinnati Reds.
Why the Cleveland Guardians will win
- The Reds have lost each of their last four day games against American League opponents following a road win.
- The Guardians have won eight of their last 10 day games at Progressive Field following a loss.
- The Reds have failed to cover the run line in each of their last four day games against American League opponents following a road win.
- The Guardians have covered the run line in each of their last four home games against NL Central opponents following a loss.
- The Reds have trailed after 3 innings in six of their last seven games at Progressive Field.
Why the Cincinnati Reds will win
- The Reds have won each of their last five games as underdogs against American League opponents.
- The Guardians have lost each of their last four games as favorites against National League opponents.
- The underdogs have covered the run line in each of the Reds’ last six games.
- The Guardians have failed to cover the run line in seven of their last eight games as favorites against National League opponents following a home loss.
- The Guardians have trailed after 5 innings in each of their last 10 Wednesday day games against opponents that held a winning record.
- The Guardians have trailed after 3 innings in four of their last five day games against NL Central opponents that held a winning record.
Cleveland Guardians Player Prop Facts
- Jose Ramirez has hit a home run in three of the Guardians’ last four games as home favorites against NL Central opponents.
- Carlos Santana has recorded at least one RBI in nine of his last 10 appearances with the Guardians as home favorites against the Reds.
- Jose Ramirez has scored at least one run in each of the Guardians’ last six games as home favorites against NL Central opponents.
- Jose Ramirez has recorded a Single in each of the Guardians’ last seven home games.
- Nolan Jones has recorded at least one hit in each of his last six appearances in day games against NL teams that held a winning record.
- Jose Ramirez ranks 4th amongst qualified players for Batting Average (.332) this season.
Cincinnati Reds Player Prop Facts
- Will Benson has hit at least one home run in three of the Reds’ last five games against the Guardians.
- Nick Lodolo has recorded five or more strikeouts in each of his last four road appearances.
- TJ Friedl has recorded at least one hit in each of his last 17 road appearances against AL Central opponents.
- Jose Trevino has recorded a Double in six of his last seven appearances with the Reds as underdogs against AL opponents.
- Jeimer Candelario has scored at least one run in each of his last nine road appearances against AL Central opponents.
- Jeimer Candelario has recorded at least one RBI in each of his last four appearances against the Guardians.
- TJ Friedl has recorded at least one Single in each of the Reds’ last 11 road games against AL opponents that held a winning record.
- Elly De La Cruz ranks 6th in the league in Steals (20) this season.
Guardians vs Reds Prediction
The Reds are finally putting things together and look like the team we expected to see out of the gate. The Reds will be a team to watch over the next month. Lodolo has been sharp with his 3.21 ERA and 1.08 WHIP, and he’s been at his best through 43.1 road innings, where he has a 1.25 ERA and .195 allowed batting average.
The Guardians have been sluggish offensively during this losing stretch, and Allen has been hittable this season, allowing 15 earned runs in his last 29.1 innings. Allen has a .280 allowed batting average on the season and has 27 walks with 40 strikeouts. Give me the Reds and the cheap price, as they’re in better form and have the hotter pitcher on the bump.