Mariners vs White Sox Prediction 5/10/26 MLB Picks Today

In this article, we will formulate a Mariners vs White Sox Prediction for this MLB matchup on Sunday, May 10^th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago White Sox Preview

The Chicago White Sox have a 18-21 record this season and are sitting in the third place of the AL Central. They have an 8-9 home record and are coming off a 6-1 win at home against the Mariners. They will face the Royals and the Cubs next.

The White Sox have a .232 batting average this season, .324 OBP and .391 Slugging percentage. Chicago’s pitching staff has a 4.32 ERA and 1.37 WHIP. Chase Meidroth is the team’s best hitter with a .277 batting average. Munetaka Murakami leads the team in RBI with 29, also adding a team‑high 15 home runs.

Davis Martin (R) is the projected starting pitcher for the White Sox, and he has a 5-1 record, 1.64 ERA and 1.02 WHIP.

Seattle Mariners Preview

The Seattle Mariners have a 19-21 record this season and are sitting in the second place of the AL West. They have a 7-10 away record and are coming off a 1-6 loss on the road against the White Sox. They will face the Astros and the Padres next.

The Mariners have a .230 batting average this season, .320 OBP and .379 Slugging percentage. Seattle’s pitching staff has a 3.81 ERA and 1.24 WHIP. Randy Arozarena is the team’s best hitter with a .278 batting average. Luke Raley leads the team in RBI with 23, also adding a team‑high 8 home runs.

Logan Gilbert (R) is the projected starting pitcher for the Mariners, and he has a 2-3 record, 4.30 ERA and 1.30 WHIP.

Seattle Mariners @ the Chicago White Sox Betting Trends: May 10, 2026

• Probable Starting Pitcher: Davis Martin      Record this season: 5-1      ERA: 1.64
• Home Record: 2-0
• Last 5 against Mariners: 0-2

Why the Chicago White Sox will win

• The White Sox have won six of their last seven games as underdogs after playing the previous day.
• The Mariners have lost four of their last five games as road favorites following a loss.
• The White Sox have covered the run line in each of their last 11 home games against American League opponents following a home win.
• The Mariners have failed to cover the run line in five of their last six games after playing the previous day.
• The White Sox have won the first inning in each of their last three games as underdogs.
• The Mariners have trailed after 5 innings in eight of their last nine games as road favorites against American League opponents.
• The White Sox have led after 3 innings in eight of their last nine games as underdogs against American League opponents.

• Probable Starting Pitcher: Logan Gilbert      Record this season: 2-3      ERA: 4.30
• Road Record: 0-1
• Last 5 against White Sox: 2-0

Why the Seattle Mariners will win

• The Mariners have won each of their last six games against the White Sox following a loss.
• The White Sox have lost each of their last five games against the Mariners following a win.
• The Mariners have covered the run line in six of their last seven day games against the White Sox following a loss.
• The White Sox have failed to cover the run line in five of their last six games as underdogs against the Mariners following a win.
• The Mariners have led after 5 innings in four of their last five games against the White Sox.
• The Mariners have led after 3 innings in nine of their last 10 day games against AL Central opponents that held a losing record.

Total Runs Facts

• Seven of the White Sox’s last eight games after playing the previous day have gone UNDER the total runs line.
• Five of the Mariners’ last six games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Mariners’ last seven day games against AL Central opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the White Sox’s last six day games at Rate Field.

Chicago White Sox Player Prop Facts

• Miguel Vargas has recorded at least one hit in each of the White Sox’s last 12 games as underdogs.
• Austin Hays has hit a home run in two of his last three appearances against the Mariners.
• Munetaka Murakami ranks T1st in the league in Home Runs (15) this season.

Seattle Mariners Player Prop Facts

• Julio Rodriguez has hit a home run in four of his last seven appearances against the White Sox after playing the previous day.
• Logan Gilbert has recorded a win in three of his last four appearances with the Mariners as road favorites.
• Logan Gilbert has recorded seven or more strikeouts in seven of his last eight appearances in day games against AL teams that held a losing record.
• Julio Rodriguez has recorded at least one hit in each of the Mariners’ last 11 day games against opponents that held a losing record.
• Randy Arozarena ranks T9th in the league in Steals (9) this season.

Matchup/League Facts

• The White Sox rank 30th in the league for doubles this season (43).
• The White Sox rank T26th in the league for hits this season (299).
• The Mariners rank 1st in the league for walks allowed this season (98).
• The Mariners rank 28th in the league for doubles this season (51).

Mariners vs White Sox Prediction

The Mariners are 8-2 in their last 10 meetings against the White Sox and are 5-2 in their last 7 meetings in Chicago.

In this Mariners vs White Sox Prediction, the Mariners are coming as -130 road favorites. The White Sox destroyed the Mariners yesterday and are home dogs today with Davis Martin on the mound, who has a 1.64 ERA and has been unhittable at home with a 0.77 home ERA. On top of that, the White Sox also have a better offense and Gilbert has been up and down this season, so I like the value with the home team in this one. Take the White Sox on the moneyline for plus money.