Marlins vs Padres Prediction 5/27/25 MLB Picks Today

The Miami Marlins are visiting the San Diego Padres on Tuesday, May 27^th at the Petco Park in the second game of this series, with the Padres having a 1-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Marlins vs Padres Prediction. We will examine:

The San Diego Padres’ recent form and player performance

The Miami Marlins’ recent form and player performance

Recent betting trends and streaks involving the San Diego Padres

Recent betting trends and streaks involving the Miami Marlins

Recent betting trends in games played between the Miami Marlins vs San Diego Padres

A summary that ties it all together and produces a favorable betting outcome for the Miami Marlins vs San Diego Padres game

San Diego Padres Preview

The San Diego Padres have a 30-22 record this season and are sitting in second place in the NL West. They have a 17-8 home record, and are 21-29 in over/under. The Padres are coming off a 4-3 home victory over the Marlins and have back-to-back wins. Under is 9-2-1 in their last 12 games, and they are playing the Giants and the Pirates next.

The Padres have a .251 batting average this season, a .317 OBP, and a .388 Slugging percentage. San Diego’s pitching staff has a 3.49 ERA and 1.19 WHIP.  Manny Machado leads the Padres with 61 hits and a team-high .319 batting average. Gavin Sheets leads the team in RBI, with 31, while Fernando Tatis Jr. adds a team-high 12 home runs.

Stephen Kolek (R) will take the mound for the Padres, and he has a 2-1 record, 2.84 ERA, and 1.26 WHIP. He struggled in his only home start this season, as he gave up 5 runs in 5 innings pitched in a 5-1 loss to the Mariners. This will be his first career start versus the Marlins.

Miami Marlins Preview

The Miami Marlins have a 21-31 record this season and are sitting in last place in the NL East. The Marlins have an 8-16 road record and are 30-22 in over/under. They are coming off a 3-4 road defeat by the Padres, which ended their previous two-game winning streak. Under is 4-1 in their last 5 games, and they are playing the Rockies and the Giants next.

The Marlins have a .249 batting average this season, a .314 OBP, and a .387 slugging percentage. Miami’s pitching staff has a 5.21 ERA and 1.44 WHIP.  Kyle Stowers leads the Marlins with 54 hits, adding team-highs in RBI with 31, in home runs with 10, and is the team’s best hitter with a .300 batting average.

Max Meyer (R) will take the mound for the Marlins, and he has a 3-4 record, 4.15 ERA, and 1.28 WHIP. He has been weaker on the road with a 5.16 ERA across four road starts, but he is coming off a quality start against the Cubs, with just one earned run in 6 innings pitched. This will be his first career start versus the Padres.

Why the San Diego Padres will win

• The Padres have won each of their last 10 night games against National League opponents that held a losing record.
• The Marlins have lost 11 of their last 12 games against NL West opponents that held a winning record.
• The Padres have covered the run line in each of their last seven home games against National League opponents following a home win.
• The Marlins have failed to cover the run line in five of their last six games against National League opponents after going to extra innings.
• The Marlins have trailed after 3 innings in seven of their last eight night games against NL West opponents that held a winning record.
• The Marlins have lost the first inning in four of their last five night games against NL West opponents.
• The Padres have led after 5 innings in each of their last six Tuesday home games.

Why the Miami Marlins will win

• The Padres have lost five of their last six games as favorites.
• The underdogs have won three of the Padres’ last four games at Petco Park.
• The Padres have failed to cover the run line in each of their last six games as favorites.
• The Marlins have covered the run line in each of their last five road games after playing the previous day.
• The Padres have lost the first inning in three of their last four night games against NL East opponents.
• The Padres have trailed after 5 innings in seven of their last eight games.
• The Marlins have led after 3 innings in four of their last five road games.

Total Runs Facts

• Seven of the last eight games between the Marlins and Padres at Petco Park have gone UNDER the total runs line.
• Seven of the Marlins’ last eight road games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Padres’ last eight night games against NL East opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Marlins’ last eight road games.

Matchup/League Facts

• The Padres rank 1st in the league for strikeouts against this season (371).
• The Padres rank 3rd in the league for opponent batting average this season (.223).
• The Marlins rank 27th in the league for ERA this season (5.21).
• The Marlins rank 27th in the league for runs allowed this season (289).

Marlins vs Padres Prediction

The Padres are 8-3 in their last 11 meetings against the Marlins, and are 4-1 in their last 5 meetings in San Diego. Under is 6-1 in their last 7 meetings in San Diego.

In this Marlins vs Padres Prediction, the Padres are coming as -185 home favorites. The Padres are rightfully favored, as they have been the better team this season and have been extremely strong at home, while the Marlins have been struggling on the road. San Diego also has a better bullpen, and Kolek has been very good so far this season, while Meyer managed to keep the league’s best offense in check in his last start. Both teams are 13-3-1 to the under in their last 17 games combined, and six of their last seven meetings in San Diego were low-scoring ones. Take the under 7.5 in this one.