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Marlins vs Pirates Prediction 3/28/25 MLB Picks Today

Pittsburgh Pirates (0-1) vs. Miami Marlins (1-0)
March 28, 2025 7:10 pm EDT
The Line: Miami Marlins +120 / Pittsburgh Pirates -142; Over/Under: 7.5
(Get latest betting odds)

The Pittsburgh Pirates and the Miami Marlins meet on Friday in MLB action from LoanDepot Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Marlins vs Pirates Prediction.

Starting Pitching Matchup

The Pittsburgh Pirates will start Mitch Keller here, and Keller was 11-12 with a 4.25 ERA and 166 strikeouts last season. In his last five starts against Miami, Keller is 1-0 with a 3.58 ERA and 22 strikeouts. Connor Gillispie will get the start for the Marlins here and was 0-0 with a 2.25 ERA and 8 strikeouts last season. This will be Gillispie’s first career start.

Pittsburgh Pirates Recap

The Pittsburgh Pirates will be out to bounce back after ending up with a 5-4 loss at the hands of the Marlins in Thursday’s series & season opener. After this four-game set, the Pirates will continue on the road for an interleague series with Tampa Bay.

Pirates Looking To Get Revenge In Friday’s Rematch

Nick Gonzales launched a two-run home run, and Bryan Reynolds went 1 for 4 with the other two RBIs for Pittsburgh in the loss, and Tommy Pham’s lone base knock ended up as a double. KeBryan Hayes added a base hit as the Pirates managed just four hits as a team, with Pittsburgh combining for 11 strikeouts and a 1 for 9 mark with runners in scoring position. Paul Skenes allowed two runs on three hits with 7 strikeouts over 5.1 innings of work, not factoring in the decision. Colin Holderman blew the save, and David Bednar allowed the walk-off run to take the loss, falling to 0-1 on the year.

Why the Pittsburgh Pirates will win

  • The Marlins have lost each of their last 10 night games against National League opponents following a win.
  • The Pirates have won eight of their last nine games against the Marlins.
  • The Marlins have failed to cover the run line in each of their last six night games at LoanDepot Park following a win.
  • The Pirates have covered the run line in six of their last seven night games against NL East opponents following a road loss.

Pittsburgh Pirates Player Prop Facts

  • Andrew McCutchen has hit at least one home run in 12 of his last 30 appearances with the Pirates as road favorites against NL opponents.
  • Bryan Reynolds has recorded a Double in six of the Pirates’ last eight games as road favorites against NL East opponents.
  • Bryan Reynolds has recorded at least one RBI in eight of his last nine appearances with the Pirates as favorites against the Marlins.
  • Mitch Keller has recorded six or more strikeouts in four of his last five appearances with the Pirates as favorites against NL East opponents.
  • Bryan Reynolds has recorded at least one Single in each of the Pirates’ last six night games against NL East opponents that held a winning record.
  • Bryan Reynolds has recorded at least one hit in each of his last nine appearances against the Marlins.
  • Mitch Keller has recorded a win in three of his last four appearances against NL East opponents.
  • Jack Suwinski has scored a run in each of his last six appearances with the Pirates as road favorites against NL opponents.
  • Ke’Bryan Hayes ranks T1st in the league in Steals (2) this season.

Miami Marlins Recap

The Miami Marlins will try to keep the ball rolling after a 5-4 win over the Pirates in Thursday’s opener. After this four-game set, the Marlins will welcome the New York Mets to town for an early NL East division series.

Marlins Trying To Start The Year 2 For 2

Xavier Edwards, Kyle Stowers, Otto Lopez, and Dane Myers each had a hit and an RBI in the win, while Nick Fortes had a triple and Derek Hill chipped in a double. Graham Pauley and Jonah Bridge each had a base hit as well to cap off the offense for Miami in the winning effort. Miami went 4 for 11 with runners in scoring position in the win. Sandy Alcantara gave up two runs on two hits with 7 strikeouts over 4.2 innings of work, not factoring in the decision. Jesus Tinoco picked up the win in relief to start the year 1-0.

Why the Miami Marlins will win

  • The Marlins have won each of their last five games as underdogs.
  • The Pirates have lost three of their last four games as favorites.
  • The Marlins have covered the run line in seven of their last eight games.
  • The Pirates have failed to cover the run line in each of their last four games as favorites.

Miami Marlins Player Prop Facts

  • Jonah Bride has recorded at least one RBI in each of the Marlins’ last four games against opponents that held a losing record.
  • Otto Lopez has scored a run in four of the Marlins’ last five games against NL Central opponents.
  • Otto Lopez has recorded at least one Single in each of his last seven appearances.
  • Jonah Bride has recorded at least one hit in each of the Marlins’ last nine games as underdogs.
  • Jesus Sanchez has hit a home run in four of his last eight home appearances against NL Central opponents.

Total Runs Facts

  • Eleven of the Marlins’ last 12 night games against NL Central opponents have gone OVER the total runs line.
  • Each of the Pirates’ last three games have gone OVER the total runs line.

Marlins vs Pirates Prediction

I’m on the Pirates here. I think it was a lot easier to make a case for the Marlins on Thursday, as Sandy Alcantara is an ace-level pitcher that will always give the Marlins a chance whenever he takes the mound. However, Friday is a bit tougher, with Connor Gillispie logging just 8 major league innings to this point. Mitch Keller isn’t my favorite arm in the Pirates’ rotation, but I think he’ll be good enough here. I’m not backing down that I think the Marlins have one of the worst lineups in baseball, but even the worst teams in baseball normally win 50–60 games a year. I think the Pirates get their get back here. Give me the Pirates.

Chris Ruffolo's Free Pick: Pittsburgh Pirates -142

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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