Brewers vs Diamondbacks Prediction 8/28/25 MLB Picks Today

The Arizona Diamondbacks and the Milwaukee Brewers meet Tuesday in MLB action from American Family Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Brewers vs Diamondbacks Prediction.

Starting Pitching Matchup

The Arizona Diamondbacks will send out Nabil Crismatt for the start here and Crismatt is 1-0 with a 1.00 ERA and 9 strikeouts this season. This will be Crismatt’s first career start against the Brewers. Jose Quintana will get the start here for the Brewers and is 10-4 with a 3.32 ERA and 75 strikeouts this season. In his last five starts against the Diamondbacks, Quintana is 1-0 with a 3.70 ERA and 12 strikeouts.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to add on to their 3-2 win over the Brewers from Wednesday’s matchup to sit at 65-69 on the year. After this series, the Diamondbacks will head on the road for a division series against the Dodgers.

Diamondbacks Snap Three-Game Losing Streak

Corbin Carroll has 120 hits with 27 home runs, 67 RBIs, 16 triples and 25 doubles this season. Carroll also has 20 stolen bases and Geraldo Perdomo has a team-high 23 stolen bases as well as 15 home runs and 87 RBIs with a team-high 143 hits this season. Ketel Marte’s added 23 home runs and 60 RBIs as well on the year and Lourdes Gurriel has 119 hits with 23 doubles, 19 home runs and 80 RBIs.

Why the Arizona Diamondbacks will win

• The Diamondbacks have won each of their last six Thursday day games as underdogs against NL Central opponents.
• The Brewers have lost three of their last four games as favorites following a loss.
• The Diamondbacks have covered the run line in each of their last 11 games as road underdogs following a win.
• The Brewers have failed to cover the run line in eight of their last nine games as favorites.

Arizona Diamondbacks Player Prop Facts

• Geraldo Perdomo has hit a home run in three of the Diamondbacks’ last five games as underdogs.
• Geraldo Perdomo has recorded at least one hit in each of the Diamondbacks’ last 14 games against NL opponents that held a winning record.
• Geraldo Perdomo ranks 3rd amongst qualified players for On Base Percentage (.394) this season.

Milwaukee Brewers Recap

The Milwaukee Brewers come into this game looking to rebound from their loss at the hands of the Diamondbacks on Wednesday to drop to 83-51 this season. After this series, the Brewers will head north for a series against the Toronto Blue Jays.

Brewers Looking For Bounce Back Performance

Brice Turang has 137 hits with 15 home runs, 67 RBIs and 22 stolen bases while Jackson Chourio has 123 hits with a team-high 29 doubles, 22 stolen bases, 17 home runs and 67 RBIs and Sal Frelick has 129 hits as well as 3 triples, 9 home runs, 51 RBIs and 18 stolen bases so far this season. Christian Yelich also has 15 stolen bases with 26 homers and 90 RBIs while also adding 16 doubles. Yelich also has a team-high 145 strikeouts up to this point in the year. William Contreras has 16 homers and 66 RBIs as well this season. Joey Ortiz has chipped in 93 hits with 17 doubles, 7 home runs and 43 RBIs and Caleb Durbin also has 21 doubles with 9 homers and 45 RBIs. 

Why the Milwaukee Brewers will win

• The Brewers have won 10 of their last 11 day games following a loss.
• The Diamondbacks have lost each of their last four day games against the Brewers following a road win.
• The Brewers have covered the run line in each of their last six Thursday games against National League opponents.
• The Diamondbacks have failed to cover the run line in four of their last five day games against teams that held a winning record.

Milwaukee Brewers Player Prop Facts

• Jose Quintana has recorded six or more strikeouts in three of his last four appearances in day games against NL teams that held a losing record.
• Jose Quintana has recorded a win in seven of his last nine appearances against NL opponents that held a losing record.
• William Contreras has hit a home run in three of the Brewers’ last four games against the Diamondbacks.
• Brice Turang has recorded at least one hit in each of his last 13 appearances against NL West opponents.
• Sal Frelick ranks 10th amongst qualified players for Batting Average (.297) this season.

Total Runs Facts

• Five of the Brewers’ last six day games against NL West opponents have gone UNDER the total runs line.
• Four of the Diamondbacks’ last five day games against NL Central opponents have gone UNDER the total runs line.

Brewers vs Diamondbacks Prediction

I’ll take a shot on Arizona here. I get the case to be made for the Brewers at home, but the problem is I think Quintana is due to get hit at some point. This could happen here against a Diamondbacks team that has been steadily improving against left-handed pitching despite trading some pieces away at the deadline. The Brewers were playing with fire early on in this series, and I think that their focus might be on this marquee weekend series against Toronto. Give me Arizona in this one.