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Nationals vs Cubs Prediction 3/26/26 MLB Picks Today

Washington Nationals (0-0) vs. Chicago Cubs (0-0)
March 26, 2026 2:20 pm EDT
The Line: Chicago Cubs -226 / Washington Nationals 184; Over/Under: 8
(Get latest betting odds)

In this article, we will formulate a Nationals vs Cubs Prediction for this MLB matchup on Thursday, March 26th. Let’s take a look at the prediction for this MLB matchup.

Chicago Cubs Preview

The Chicago Cubs finished last season with a 92-70 record and were placed 2nd in the NL Central. They had a 50-31 home record and 42-39 away record and were 77-80-13 in over/under.

Last season the Cubs had a .249 batting average, .320 OBP and .430 Slugging percentage. Chicago’s pitching staff had a 3.79 ERA and 1.18 WHIP. Nico Hoerner led the Cubs with 178 hits, and he was the team’s best hitter with a .297 batting average. Seiya Suzuki led the team in RBI, with 103 and added a team-high 32 home runs.

Matthew Boyd (L) is the projected starting pitcher for the Cubs, and last season he had a 14-8 record, 3.21 ERA and 1.09 WHIP.

Washington Nationals Preview

The Washington Nationals finished last season with a 66-96 record and were placed 5th in the NL East. They had a 32-49 home record and 34-47 away record and were 81-70-11 in over/under.

Last season the Nationals had a .242 batting average, .304 OBP and .389 Slugging percentage. Washington’s pitching staff had a 5.35 ERA and 1.45 WHIP. James Wood led the Nationals with 153 hits, and he was the team’s best hitter with a .256 batting average. James Wood also led the team in RBI, with 83 and added a team-high 31 home runs.

Cade Cavalli (R) is the projected starting pitcher for the Nationals, and last season he had a 3-1 record, 4.25 ERA and 1.48 WHIP.

Washington Nationals @ the Chicago Cubs Betting Trends: March 26, 2026

 

  • Probable Starting Pitcher: Matthew Boyd      Record this season: –      ERA: –
  • Home Record: –
  • Last 5 against Nationals: 1-2

Why the Chicago Cubs will win

  • The Nationals have lost each of their last nine Thursday games against NL Central opponents.
  • The home team has won each of the Cubs’ last six games.
  • The Nationals have failed to cover the run line in each of their last seven season openers.
  • The Cubs have covered the run line in six of their last seven games as favorites.
  • The Cubs have led after 3 innings in six of their last seven games as home favorites against NL East opponents.
  • The Cubs have led after 5 innings in each of their last seven games as favorites.

 

  • Probable Starting Pitcher: Cade Cavalli      Record this season: –      ERA: –
  • Road Record: –
  • Last 5 against Cubs: –

Why the Washington Nationals will win

  • The Nationals have won four of their last five games as underdogs against NL Central opponents.
  • The Cubs have lost three of their last four games as home favorites against NL East opponents.
  • The road team has covered the run line in seven of the Nationals’ last eight games.
  • The Cubs have failed to cover the run line in seven of their last eight day games against NL East opponents.
  • The Nationals have led after 5 innings in each of their last four day games against National League opponents.
  • The Nationals have led after 3 innings in five of their last six road games.

Total Runs Facts

  • Each of the Cubs’ last four home games against NL East opponents have gone OVER the total runs line.
  • Five of the Nationals’ last six road games against NL Central opponents have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Cubs’ last five games.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Nationals’ last six Thursday games against NL Central opponents.

Chicago Cubs Player Prop Facts

  • Ian Happ has recorded a Double in four of the Cubs’ last five games against NL East opponents.
  • Matthew Boyd has recorded a win in eight of his last 10 appearances with the Cubs as home favorites against NL opponents.
  • Seiya Suzuki has recorded at least one hit in each of his last 14 home appearances.
  • Seiya Suzuki has hit a home run in four of the Cubs’ last six games as favorites.

Washington Nationals Player Prop Facts

  • CJ Abrams has recorded at least one hit in each of his last 11 road appearances against NL Central opponents.
  • Luis Garcia has hit a home run in four of his last 10 road appearances against NL opponents.

Nationals vs Cubs Prediction

Both teams were tied 3-3 in their 6 meetings last season, with each team winning one series by 2-1 wins. The Nationals won the series in Chicago by 2-1 and the under is 6-3 in their last 9 meetings.

In this Nationals vs Cubs Prediction, the Cubs are coming as -200 home favorites. The Cubs were the far better team last season and very strong at home. Boyd was far better at home as well, with a 2.51 home ERA, while Cavalli was terrible on the road for the Nationals, with a 6.17 road ERA. On top of that, Washington was just 26th in baseball against left-handed pitching last season, so everything points towards a comfortable Chicago win. Take the Cubs on the runline in this one.

Nikos Lagouretos's Free Pick: Chicago Cubs -1.5

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