Nationals vs Diamondbacks Prediction 4/6/25 MLB Picks Today

In this article we will formulate a Nationals vs Diamondbacks prediction for this MLB game on Sunday, April 6th at Nationals Park in Washington, DC. Let’s take a look at the prediction for this MLB matchup. 

Washington Nationals Betting Preview

The Washington Nationals are 2-6 this year after they won game two by a score of 4-3 on Saturday. Washington scored the first four runs in the game, but they allowed the last three and barely held off the Diamondbacks in the ninth for the win. The Nationals recorded six hits and committed one error in the game, while they were led by Wood and Call, who both had two RBIs. Washington started Parker, who allowed two hits and one earned run over 6.0 innings, while Finnegan allowed one hit and one earned run in the ninth, but still got the save. 

Prior to this series, the Nationals were swept in three games by the Blue Jays and they lost two out of three against the Phillies. The Washington pitching staff has a 4.89 ERA with a 1.59 WHIP and a .285 opponent batting average, while their offense has scored 29 runs with a .216 batting average and a .272 on base percentage this season. Nathaniel Lowe has led Washington with three home runs and seven RBIs, while CJ Abrams has added three home runs and five RBIs this year. The projected starting pitcher for Washington is Brad Lord, who is 0-0 with a 4.50 ERA and a 2.50 WHIP over 2.0 innings pitched this year. 

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 5-4 this season after they dropped game two in this series, but they did win game one by a score of 6-4. In that game two loss, Arizona fell behind 4-0 in the fourth, but they scored one in the sixth, one in the seventh, and one in the ninth in the close loss. The Diamondbacks recorded five hits in the game and they were led by Grichuk, Thomas, and Tawa, who all had one RBI in the loss. Arizona started Rodriguez, who allowed five hits and four earned runs over 5.0 innings, while Jarvis and Mantiply combined for 3.0 scoreless innings out of the pen. 

Prior to this series, the Diamondbacks won two out of three against the Yankees and split four games with the Cubs. The Arizona pitching staff has a 5.01 ERA with a 1.19 WHIP and a .224 opponent batting average, while their offense has scored 54 runs with a .261 batting average and a .353 on base percentage this year. Eugenio Suarez has led Arizona with five home runs and 11 RBIs, while Geraldo Perdomo has added one home run and 11 RBIs this season. The projected starting pitcher for Arizona is Corbin Burnes, who is 0-0 with a 4.15 ERA and a 1.62 WHIP over 4.1 innings pitched this year. 

Why the Diamondbacks will beat the Nationals

• The Diamondbacks have won each of their last seven day games against National League opponents following a loss.
• The Nationals have lost 12 of their last 13 games against NL West opponents that held a winning record.
• The Nationals have failed to cover the run line in each of their last eight games against the Diamondbacks following a win.
• The Diamondbacks have covered the run line in each of their last five road games against the Nationals following a loss.
• The Diamondbacks have led after 5 innings in nine of their last 10 games against the Nationals at Nationals Park.
• The Diamondbacks have led after 3 innings in four of their last five road day games.

Total Runs Facts

• Seven of the Diamondbacks’ last eight day games after playing the previous day have gone OVER the total runs line.
• Each of the Nationals’ last five games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Diamondbacks’ last eight road games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the last five games between the Diamondbacks and Nationals.

Washington Nationals Player Prop Facts

• Trevor Williams has recorded four or more strikeouts in each of his last six appearances in day games against NL West teams that held a winning record.
• Trevor Williams has recorded a win in three of his last four home appearances against opponents that held a winning record.
• Nathaniel Lowe has hit a home run in three of the Nationals’ last four games against NL opponents.
• Amed Rosario has recorded at least one Single in each of his last eight appearances against NL West opponents.
• Amed Rosario has scored at least one run in eight of his last nine appearances at Nationals Park against opponents that held a winning record.
• Amed Rosario has recorded at least one RBI in five of his last six appearances against NL West opponents.
• Amed Rosario has recorded at least one hit in each of his last nine appearances at Nationals Park against opponents that held a winning record.

Arizona Diamondbacks Player Prop Facts

• Randal Grichuk has recorded a Double in three of his last four appearances against the Nationals after playing the previous day.
• Corbin Burnes has recorded six or more strikeouts in eight of his last 10 road appearances against NL East opponents.
• Ketel Marte has hit a home run in three of his last four road appearances with the Diamondbacks against NL opponents.
• Josh Naylor has recorded at least one Single in nine of his last 10 appearances against opponents that held a losing record.
• Corbin Carroll has scored at least one run in seven of the Diamondbacks’ last eight games against NL East opponents that held a losing record.
• Randal Grichuk has recorded at least one RBI in six of the Diamondbacks’ last seven day games.
• Lourdes Gurriel Jr. has recorded at least one hit in 17 of his last 18 road appearances against NL East opponents.

Nationals vs Diamondbacks Prediction 

Washington was able to pickup their second win of the season on Saturday afternoon and they will look for their first series win of 2025 with a win here. The Nationals have struggled with their hitting and pitching through their first eight games, and they don’t have a clear plan for their starter for this one. Arizona is 5-4 to start the season and they have a very dangerous lineup, but their pitching staff has also struggled. The Diamondbacks will be starting Burnes in this game, who didn’t look very good in his first outing, but should be fine against this Washington lineup. Take the Diamondbacks to win by at least two runs here.