NY Yankees vs St. Louis Cardinals Prediction 8/4/26 MLB Picks Today

The St. Louis Cardinals and the New York Yankees meet Tuesday in MLB action from Yankee Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a St. Louis Cardinals vs. New York Yankees prediction.

Starting Pitching Matchup

The St. Louis Cardinals will send out Hunter Dobbins for the start here and Dobbins is 2-1 with a 3.74 ERA and 32 strikeouts this season. Ryan Weathers will start here for New York and is 4-7 with a 3.99 ERA and 126 strikeouts this season.

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to add on to their 13-7 win over New York from Monday’s opener to improve to 56-57 on the year. After this series, the Cards will head home for a series against the Colorado Rockies.

Cardinals Win Back-To-Back Games

Jordan Walker has 123 hits, 23 doubles, 22 home runs and 81 RBIs while Alec Burleson has 124 hits with 27 doubles, 18 home runs and 77 RBIs. JJ Wetherholt has 104 hits with 16 home runs and 41 RBIs while Ivan Herrera has 100 hits with 18 doubles, 12 home runs and 46 RBIs. Nolan Gorman has 39 hits with 7 home runs and 26 RBIs this season. Masyn Winn’s added 90 hits with 14 doubles and 45 RBIs and Nathan Church has 66 hits with 9 home runs and 35 RBIs this season.

New York Yankees Recap

The New York Yankees come into this game looking to shake off Monday’s loss at the hands of St. Louis to sit at 63-50 this season. After this series, the Yankees will take on the Atlanta Braves in a series at home.

Yankees Alternate Wins & Losses In 5 Straight

Ben Rice has 106 hits with 19 doubles, 31 home runs and 73 RBIs and Aaron Judge has 53 hits with 10 doubles, 17 home runs and 38 RBIs. Cody Bellinger also has 97 hits with 21 doubles, 3 triples, 11 home runs and 53 RBIs. Jazz Chisholm Jr. also has 81 hits with 14 doubles, 16 home runs and 45 RBIs as well on the year.

St. Louis Cardinals @ New York Yankees Betting Trends: August 4, 2026

• Probable Starting Pitcher: Ryan Weathers      Record this season: 4-7      ERA: 3.99
• Home Record: 2-5
• Last 5 against Cardinals: 0-0

Why the New York Yankees will win

• The Cardinals have lost seven of their last eight games against AL East opponents that held a winning record.
• The Yankees have won seven of their last eight night games against National League opponents following a home loss.
• The Yankees have covered the run line in each of their last four night games against National League opponents following a loss.
• The Cardinals have failed to cover the run line in five of their last six games against teams that held a winning record.
• The Yankees have led after 3 innings in eight of their last 10 home games against National League opponents that held a losing record.
• The Cardinals have lost the first inning in four of their last five night games against AL East opponents that held a winning record.
• The Cardinals have trailed after 5 innings in six of their last seven night games against AL East opponents that held a winning record.

• Probable Starting Pitcher: Hunter Dobbins      Record this season: 2-1      ERA: 3.74
• Road Record: 1-0
• Last 5 against Yankees: 2-0

Why the St. Louis Cardinals will win

• The Yankees have lost seven of their last eight games as home favorites after playing the previous day.
• The Cardinals have won seven of their last eight games as underdogs against AL East opponents following a road win.
• The Yankees have failed to cover the run line in eight of their last nine home games against teams that held a losing record.
• The Cardinals have covered the run line in eight of their last nine games against AL East opponents following a road win.
• The Yankees have trailed after 3 innings in six of their last seven games against opponents that held a losing record.
• The Yankees have lost the first inning in each of their last four night games against National League opponents.
• The Yankees have trailed after 5 innings in 10 of their last 11 games against opponents that held a losing record.

Total Runs Facts

• Seven of the Cardinals’ last eight games as underdogs against the Yankees have gone OVER the total runs line.
• Each of the last five games between the Cardinals and Yankees at Yankee Stadium have gone OVER the total runs line.
• There has been at least one run scored in the first inning in each of the Yankees’ last four night games against National League opponents.
• There has been no run scored during the first inning in five of the Cardinals’ last six games.

New York Yankees Player Prop Facts

• Trent Grisham has hit a home run in three of his last four appearances in night games against teams that held a losing record.
• Ryan Weathers has recorded six or more strikeouts in three of his last four appearances with the Yankees as favorites.
• Jasson Dominguez has recorded at least one hit in each of his last 18 appearances with the Yankees as favorites against NL opponents.
• Jazz Chisholm ranks T2nd in the league in Steals (30) this season.

St. Louis Cardinals Player Prop Facts

• Hunter Dobbins has recorded a win in each of his last three appearances with his team as an underdog against AL opponents.
• Hunter Dobbins has recorded five or more strikeouts in three of his last four appearances with his team as an underdog against AL opponents.
• Jordan Walker has recorded at least one hit in each of the Cardinals’ last nine games as road underdogs against AL East opponents.
• Jimmy Crooks has hit a home run in each of his last two road appearances against opponents that held a winning record.
• Alec Burleson ranks 7th in the league in Hits (124) this season.

Matchup/League Facts

• The Yankees rank 1st in the league for ERA this season (3.37).
• The Yankees rank 2nd in the league for home runs this season (162).
• The Cardinals rank 27th in the league for doubles this season (153).
• The Cardinals rank 4th in the league for strikeouts against this season (872).

St. Louis Cardinals vs. New York Yankees Prediction

I’m on the Yankees in this one. We can talk about New York’s struggles at the plate without Aaron Judge, but we can’t forget how bad the Cardinals have been since the all-star break when it comes to facing left-handed pitching, boasting some of the worst numbers in baseball. I think the Yankees get to Dobbins here and get the job done in this one so give me New York.