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Rays vs Twins Prediction 4/25/26 MLB Picks Today

Minnesota Twins (12-14) vs. Tampa Bay Rays (14-11)
April 25, 2026 4:10 pm EDT
The Line: Tampa Bay Rays -136 / Minnesota Twins 113; Over/Under: 8
(Get latest betting odds)

In this article we will formulate a Rays vs Twins prediction for this MLB game on Saturday, April 25th at Tropicana Field in St. Petersburg, Florida. Let’s take a look at the prediction for this MLB matchup. 

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 14-11 this year after they won game one by a score of 6-2 last night. Tampa Bay scored the first three runs in the game and they were able to get the easy victory. The Rays recorded seven hits in the game and they were led by Caminero, who went 2-4 with two home runs and three RBIs. Rasmussen allowed five hits and one earned run over 6.0 innings for the win, while Martin allowed one earned run in relief. Prior to this series, Tampa Bay lost two out of three against the Reds and two out of three against the Pirates. 

This season, Tampa Bay has a 4.59 ERA with a 1.28 WHIP and a .230 opponent batting average, while they have scored 122 runs with a .256 batting average and a .332 on base percentage. Jonathan Aranda has led the Rays with six home runs and 21 RBIs, while Yandy Diaz has added three home runs and 18 RBIs. The projected starting pitcher for Tampa Bay is Shane McClanahan, who is 1-2 with a 5.00 ERA and a 1.33 WHIP over 18.0 innings pitched this year. 

Minnesota Twins Betting Preview

The Minnesota Twins are 12-14 this season after they lost game one by a score of 6-2 on Friday night. Minnesota cut the deficit to 3-1 in the fifth inning, but didn’t score again until the ninth in the loss. The Twins recorded nine hits in the game and they were led by Lewis and Lee, who both had one RBI. Bradley allowed seven hits and six earned runs over 6.1 innings for the loss, while Orze threw a scoreless inning in relief. Prior to this series, Minnesota lost two out of three against the Mets and all three against the Reds. 

This season, Minnesota has a 4.22 ERA with a 1.36 WHIP and a .251 opponent batting average, while they have scored 129 runs with a .232 batting average and a .330 on base percentage. Josh Bell has led the Twins with three home runs and 16 RBIs, while Tristan Gray has added three home runs and 13 RBIs. The projected starting pitcher for Minnesota is Bailey Ober, who is 2-0 with a 4.15 ERA and a 1.23 WHIP over 26.0 innings pitched this season. 

Why the Tampa Bay Rays will win

  • The Rays have won each of their last nine games against American League opponents.
  • The Twins have lost each of their last six games after playing the previous day.
  • The Rays have covered the run line in each of their last nine games against American League opponents.
  • The Twins have failed to cover the run line in 10 of their last 11 games against the Rays following a loss.
  • The Twins have lost the first inning in five of their last six road games.
  • The Twins have trailed after 3 innings in seven of their last eight road games against AL East opponents that held a winning record.
  • The Rays have led after 5 innings in each of their last six home day games.

Why the Minnesota Twins will win

  • The Rays have lost five of their last six games as home favorites against American League opponents.
  • The Twins have won eight of their last nine day games against American League opponents that held a winning record.
  • The Twins have covered the run line in nine of their last 10 day games against American League opponents that held a winning record.
  • The Rays have failed to cover the run line in six of their last seven home games against American League opponents that held a losing record.
  • The Twins have won the first inning in each of their last three day games.
  • The Twins have led after 3 innings in four of their last five road games against American League opponents.
  • The Twins have led after 5 innings in each of their last four day games against opponents that held a winning record.

Total Runs Facts

  • Each of the Twins’ last five road games against AL East opponents have gone OVER the total runs line.
  • Six of the Rays’ last seven home games against American League opponents have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Twins’ last seven games against American League opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Rays’ last seven day games at Tropicana Field.

Tampa Bay Rays Player Prop Facts

  • Yandy Diaz has hit a home run in four of the Rays’ last nine home games against AL opponents that held a losing record.
  • Shane McClanahan has recorded six or more strikeouts in 12 of his 13 previous home appearances against AL opponents that held a losing record.
  • Yandy Diaz has recorded at least one hit in each of his last 11 appearances against AL opponents.

Minnesota Twins Player Prop Facts

  • Byron Buxton has hit at least one home run in four of the Twins’ last seven games as underdogs.
  • Bailey Ober has recorded five or more strikeouts in four of his last five appearances in day games against teams that held a winning record.
  • Trevor Larnach has recorded a hit in each of his last seven appearances with the Twins as underdogs.

Rays vs Twins Prediction 

Tampa Bay comes into this matchup on a two game winning streak and they have scored six runs in three straight. The Rays are 6-4 at home this year, while the Twins are 5-8 on the road. Minnesota has lost three in a row and they have allowed 16 runs in their last two. The Twins are starting Ober, who has allowed two earned runs or fewer in two of his last three starts, while McClanahan has allowed two earned runs in three of his four outings. I like how both pitchers are throwing right now and I think runs could be at a premium, so I like the under here. 

David Racey's Free Pick: Under 8

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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