Reds vs Brewers Prediction 8/16/25 MLB Picks Today

Milwaukee Brewers (77-44) vs. Cincinnati Reds (64-59)
August 16, 2025 6:40 pm EDT
The Line: Cincinnati Reds 112 / Milwaukee Brewers -136; Over/Under: 9
(Get latest betting odds)

The Milwaukee Brewers and Cincinnati Reds meet Saturday in MLB action at Great American Ball Park. Here’s a Reds vs Brewers Prediction. This article will include a Reds vs Brewers Pick.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 77-44 on the year and play the Cubs, Giants, and Diamondbacks next. The Milwaukee Brewers are batting .260 on the season, have a .333 OBP, and a .409 slugging percentage. The Milwaukee Brewers pitching staff has a 3.63 ERA and a 1.23 WHIP. Jackson Chourio leads the Milwaukee Brewers with 123 hits and 67 RBI, while Brice Turang and Christian Yelich have combined for 240 hits and 143 RBI.

Quinn Priester gets the ball for the Milwaukee Brewers, and he is 11-2 with a 3.49 ERA and 95 strikeouts this season. Priester is 1-0 with a 2.45 ERA and 8 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 64-59 on the year and play the Angels, Diamondbacks, and Dodgers next. The Cincinnati Reds are batting .247 on the season, have a .319 OBP, and a .390 slugging percentage. The Cincinnati Reds pitching staff has a 3.85 ERA and a 1.24 WHIP. Elly De La Cruz leads the Cincinnati Reds with 131 hits and 76 RBI while TJ Friedl and Spencer Steer have combined for 214 hits and 97 RBI.

Zack Littell gets the ball for the Cincinnati Reds, and he is 9-8 with a 3.60 ERA and 100 strikeouts this season. Littell is 0-1 with a 1.80 ERA and 12 strikeouts in his career against the Milwaukee Brewers.

Why the Cincinnati Reds will win

The Reds have won five of their last six games as home underdogs against National League opponents following a loss.
The Brewers have lost each of their last three games as favorites against NL Central opponents following a road win.
The Reds have covered the run line in each of their last 12 games as underdogs against the Brewers following a loss.
The Brewers have failed to cover the run line in eight of their last nine games as favorites against the Reds following a win.
The Reds have won the first inning in each of their last four games as home underdogs against NL Central opponents.
The Reds have led after 5 innings in four of their last five night games at Great American Ball Park against National League opponents.
The Reds have led after 3 innings in each of their last six games as home underdogs against NL Central opponents.

Why the Milwaukee Brewers will win

The Brewers have won each of their last 13 games.
The Reds have lost four of their last five home games against NL Central opponents that held a winning record.
The Brewers have covered the run line in each of their last 14 road games.
The Reds have failed to cover the run line in each of their last four night games against NL Central opponents.
The Brewers have led after 5 innings in seven of their last eight road games.
The Brewers have led after 3 innings in six of their last seven road games against NL Central opponents.

Cincinnati Reds Player Prop Facts

Miguel Andujar has hit a home run in three of the Reds’ last four games as underdogs.
TJ Friedl has recorded at least one hit in each of his last seven home appearances after playing the previous day.
Jose Trevino has recorded at least one Double in each of his last four appearances against NL Central opponents that held a winning record.
Elly De La Cruz ranks T5th in the league in Steals (31) this season.

Milwaukee Brewers Player Prop Facts

Christian Yelich has hit at least one home run in five of the Brewers’ last six games at Great American Ball Park against opponents that held a winning record.
Brice Turang has recorded a Double in four of the Brewers’ last five road games against NL Central opponents.
Jackson Chourio has recorded at least one hit in each of his last 11 road appearances.
Quinn Priester ranks T8th in the league for Wins (11) this season.