Tigers vs Nationals Prediction 9/22/26 MLB Picks Today
Washington Nationals (73-84) vs. Detroit Tigers (74-83)
September 22, 2026 6:40 pm EDT
The Line: Detroit Tigers -157 / Washington Nationals 130; Over/Under: 8
(Get latest betting odds)
The Washington Nationals and Detroit Tigers meet Tuesday in MLB action at Comerica Park. Here’s a Tigers vs. Nationals Prediction. This article will include a Tigers vs. Nationals Pick.
Washington Nationals Betting Preview
The Washington Nationals are 73-84 on the year and play the Tigers and Mets next. The Washington Nationals are batting .247 on the season, with a .322 OBP and a .424 slugging percentage. The Washington Nationals’ pitching staff has a 4.69 ERA and a 1.39 WHIP. CJ Abrams leads the Washington Nationals with 146 hits and 99 RBI, while James Wood and Daylen Lile have combined for 277 hits and 164 RBI.
Jackson Kent gets the ball for the Washington Nationals, and he is 1-4 with a 6.40 ERA and 27 strikeouts this season. This will be Kent’s first career game against the Detroit Tigers.
Detroit Tigers Betting Preview
The Detroit Tigers are 74-83 on the year and play the Pirates next. The Detroit Tigers are batting .241 on the season and have a .319 OBP and a .401 slugging percentage. The Detroit Tigers’ pitching staff has a 3.65 ERA and a 1.22 WHIP. Kevin McGonigle leads the Detroit Tigers with 160 hits and 70 RBI, while Dillon Dingler and Riley Greene have combined for 273 hits and 164 RBI.
Drew Anderson gets the ball for the Detroit Tigers, and he is 5-6 with a 3.62 ERA and 109 strikeouts this season. This will be Anderson’s first career game against the Washington Nationals.
Why the Detroit Tigers will win
- The Nationals have lost each of their last nine road games following a road loss.
- The Tigers have won seven of their last eight home games against teams that held a losing record.
- The Tigers have covered the run line in each of their last seven games as favorites against NL opponents.
- The Nationals have failed to cover the run line in seven of their last eight games against AL opponents.
- The Nationals have lost the first inning in each of their last three games as underdogs.
- The Nationals have trailed after 3 innings in nine of their last 10 games as road underdogs.
- The Tigers have led after 5 innings in each of their last eight Tuesday home games.
Why the Washington Nationals will win
- The Tigers have lost nine of their last 10 night games against NL East opponents following a win.
- The Nationals have won five of their last seven games as road underdogs against AL opponents following a road loss.
- The Nationals have covered the run line in seven of their last eight road games against AL Central opponents.
- The Tigers have failed to cover the run line in each of their last seven Tuesday games against NL opponents.
- The Tigers have trailed after 5 innings in five of their last six games.
- The Tigers have trailed after 3 innings in four of their last five games.
Total Runs Facts
- Each of the Nationals’ last seven night games against AL Central opponents have gone OVER the total runs line.
- Seven of the last eight games between the Nationals and Tigers have gone OVER the total runs line.
- There has been at least one run scored in the first inning in each of the Nationals’ last six games.
- There has been no run scored during the first inning in seven of Drew Anderson’s last eight appearances as a starter.
Detroit Tigers Player Prop Facts
- Spencer Torkelson has hit a home run in each of the Tigers’ last three games as favorites against the Nationals.
- Spencer Torkelson has recorded at least one hit in each of his seven previous appearances against the Nationals.
- Drew Anderson has recorded four or more strikeouts in each of his last seven appearances.
Washington Nationals Player Prop Facts
- James Wood has hit a home run in three of his last five appearances with the Nationals as underdogs against AL opponents.
- James Wood has recorded at least one hit in each of his last eight appearances with the Nationals as underdogs against AL opponents.
Matchup/League Facts
- The Tigers rank 29th in the league for steals this season (55).
- The Tigers rank 4th in the league for triples this season (33).
- The Nationals rank 1st in the league for doubles this season (277).
- The Nationals rank 1st in the league for steals this season (171).
Tigers vs Nationals Prediction
The Tigers should be favored at home with Anderson on the mound as he’s been a bright spot for Detroit with a 3.62 ERA and 1.29 WHIP. However, the Nationals are a team we’ve been on lately, as they’re a losing team that’s playing through the finish line and has been able to cash some nice underdog tickets. Kent has been rough through 32.1 innings, but the bottom line is neither of these teams have anything to play for, and I usually want the more favorable price this time of year. Give me the Nationals and the plus money.