White Sox vs Brewers Prediction 4/30/25 MLB Picks Today

In this article, we will formulate a White Sox vs Brewers Prediction for this MLB game on Wednesday, April 30th, at Guaranteed Rate Field. Let’s take a look at a Chicago White Sox vs Milwaukee Brewers prediction. 

What a Strong Game for the Brewers

The Brewers come into this game with a 15-15 record overall, and they picked up a victory on Tuesday. The Brewers scored seven runs, and they ended up winning by five runs. The Brewers scored four runs in the 6th inning, and that was enough for the victory. Isaac Collins had a strong game, hitting a home run and driving in two RBIs. Freddy Peralta went six innings, giving up three hits and two runs. 

The Brewers are averaging 5.1 runs while their pitching is giving up 4.37 runs per game. The offense is ranked 5th while the pitching is ranked 15th. Jackson Churio has hit six home runs and driven in 24 RBIs. Getting the start for the Brewers will be Tobias Myers, who sits with a 0-0 record and an ERA of 4.50. Against the San Francisco Giants in his last start, he went four innings, giving up four hits and two runs. 

Why the Brewers Will Beat the White Sox

• The Brewers have lost four of their last five road games following a win.
• The White Sox have covered the run line in each of their last four games as underdogs after playing the previous day.
• The Brewers have failed to cover the run line in four of their last five games against AL Central opponents that held a losing record.
• The White Sox have led after 5 innings in five of their last six home night games.
• The White Sox have led after 3 innings in each of their last four night games against the Brewers at Rate Field.

White Sox Continue to Have Issues

Heading into the season, the White Sox knew it might be a long season, and so far that’s exactly what has happened. The White Sox have only seven wins, and on Tuesday, the pitching was a problem. The two goals were scored by Luis Robert and Andrew Benintendi on home run balls. The White Sox also used six pitchers, and with the bullpen so taxed, that is going to hurt them in this game. Bryse Wilson went 3.1 innings, giving up two hits and three earned runs. 

The White Sox are averaging 3.34 runs while their pitching is giving up 4.38 runs per game. The offense is ranked 27th, while the pitching is ranked 165th. They have a negative run differential of -1.03. Shane Smith is going to get the start for the White Sox in this game, and he comes into this game with a 1-1 record and an ERA of 2.30. Against the Twins in his last start, he went five innings, giving up four hits and zero runs. 

Why the White Sox Will Beat the Brewers

• The Brewers have lost four of their last five road games following a win.
• The White Sox have covered the run line in each of their last four games as underdogs after playing the previous day.
• The Brewers have failed to cover the run line in four of their last five games against AL Central opponents that held a losing record.
• The White Sox have led after 5 innings in five of their last six home night games.
• The White Sox have led after 3 innings in each of their last four night games against the Brewers at Rate Field.

White Sox vs Brewers Prediction

This game is going to be lower scoring. Shane Smith sits with an ERA of 2.30, and he was quite impressive in the last game against the Twins. Even against a good offensive team, he’s going to have another big game. Tobias Myers wasn’t exactly dominant in his last start, but now he gets to face off against a White Sox offense that has been awful all season. The White Sox’s bats are going to be ice cold here, and this game is going to end up staying well under the total.