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White Sox vs Royals Prediction 6/6/25 MLB Picks Today

Kansas City Royals (33-30) vs. Chicago White Sox (20-43)
June 6, 2025 7:40 pm EDT
The Line: Chicago White Sox 145 / Kansas City Royals -175; Over/Under: 8.5
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In this article, we will formulate a White Sox vs Royals prediction for this MLB game on Friday, June 6th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 20-43 this year after they split four games with Detroit by scores of 1-13, 8-1, 4-5, and 3-2. In their game four win, Chicago blew a 2-0 lead in the seventh inning, but they were able to get the win in extra innings. The White Sox recorded 11 hits in the game, and they were led by Elko, Meidroth, and Tauchman, who all had one RBI in the win. Chicago started Burke, who allowed seven hits and two earned runs over 7.0 innings, while Wilson picked up the win in relief. 


Prior to that series, the White Sox lost all three games against the Orioles and two out of three against the Mets. Chicago has lost five of their last seven games, and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.16 ERA with a 1.37 WHIP and a .247 opponent batting average, while the offense has scored 217 runs with a .223 batting average and a .296 on-base percentage this season. Miguel Vargas has led Chicago with eight home runs and 26 RBIs, while Andrew Benintendi has added six home runs and 23 RBIs this year. The projected starting pitcher for Chicago is Davis Martin, who is 2-6 with a 3.67 ERA and a 1.24 WHIP over 68.2 innings pitched this year. 

Kansas City Royals Betting Preview

The Kansas City Royals are 33-30 this season after they won two out of three against St. Louis by scores of 10-7, 5-6, and 7-5. In their game three win, Kansas City blew a 5-1 lead in the third inning, but they scored the last two runs in the game for the win. The Royals recorded 12 hits in the game, and they were led by Garcia and Perez, who both had two RBIs in the win. KC started Ragans, who allowed five hits and five earned runs over 3.0 innings, while Zerpa picked up the win and Estevez got the save. 

Prior to that series, the Royals lost two out of three against the Tigers and two out of three against the Reds. Kansas City has alternated wins and losses over its last eight games, and they are currently fourth in the AL Central standings. The Kansas City pitching staff has a 3.23 ERA with a 1.19 WHIP and a .234 opponent batting average, while the offense has scored 216 runs with a .250 batting average and a .303 on-base percentage this season. Vinnie Pasquantino has led KC with eight home runs and 36 RBIs, while Bobby Witt has added seven home runs and 35 RBIs this year. The projected starting pitcher for Kansas City is Seth Lugo, who is 3-5 with a 3.45 ERA and a 1.15 WHIP over 60.0 innings pitched this season. 

Why the White Sox will beat the Royals

  • The Royals have lost each of their last six games as favorites after playing the previous day.
  • The White Sox have won four of their last five games as underdogs following an extra-innings win.
  • The Royals have failed to cover the run line in each of their last seven games as favorites after playing the previous day.
  • The White Sox have covered the run line in each of their last six games against American League opponents after going to extra innings.
  • The Royals have trailed after 3 innings in three of their last four games against American League opponents.
  • The White Sox have led after 5 innings in 10 of their last 11 Friday night games against the Royals at Rate Field.

Why the Royals will beat the White Sox

  • The Royals have won each of their last 10 games against the White Sox.
  • The White Sox have lost each of their last 10 night games against the Royals following a win.
  • The Royals have covered the run line in each of their last 10 road games after playing the previous day.
  • The White Sox have failed to cover the run line in each of their last seven night games against the Royals following a win.
  • The White Sox have trailed after 3 innings in six of their last eight home games against AL Central opponents that held a winning record.
  • The Royals have led after 5 innings in four of their last five games against the White Sox.
  • The Royals have won the first inning in each of their last three games.

Total Runs Facts

  • Seven of the White Sox’s last eight games following an extra innings win have gone UNDER the total runs line.
  • Six of the Royals’ last seven night games after playing the previous day have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Royals’ last eight games as favorites against American League opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last three night games between the Royals and White Sox.

Chicago White Sox Player Prop Facts

  • Mike Tauchman has recorded an RBI in five of the White Sox’s last six games against AL opponents.
  • Andrew Benintendi has recorded at least one hit in eight of his last nine home appearances against former teams.
  • Mike Tauchman has recorded at least one Single in four of his last five appearances against the Royals.
  • Michael A. Taylor has scored at least one run in each of the White Sox’s last three games.
  • Andrew Benintendi has recorded a Double in three of his last four home appearances against former teams.
  • Andrew Vaughn has hit a home run in two of the White Sox’s last three home games against the Royals.

Kansas City Royals Player Prop Facts

  • Michael Massey has hit a home run in four of his last five appearances at Rate Field against AL opponents that held a losing record.
  • Bobby Witt Jr. has recorded at least one RBI in each of the Royals’ last five games against AL Central opponents that held a losing record.
  • Seth Lugo has recorded a win in eight of his last nine road appearances against AL opponents that held a losing record.
  • Bobby Witt Jr. has scored at least one run in nine of the Royals’ last 10 games against the White Sox.
  • Seth Lugo has recorded five or more strikeouts in five of his last six road appearances against AL opponents.
  • Maikel Garcia has recorded at least one hit in each of the Royals’ last 11 night games.
  • Vinnie Pasquantino has recorded at least one Single in each of the Royals’ last nine road games.
  • Maikel Garcia has recorded a Double in four of his last five appearances with the Royals as favorites.

White Sox vs Royals Prediction 

Chicago was able to split a four-game series with the Tigers earlier this week, which should give them at least a little momentum coming into this matchup. The White Sox are 14-17 at home this season, while the Royals are 14-17 on the road. Kansas City did take two out of three against the Cardinals, but they haven’t won two games in a row in their last 14 games. The Royals are starting Lugo, who has allowed seven earned runs and 11 hits over his last 9.1 innings. The White Sox are going with Martin, who has allowed two earned runs or fewer in three of his last four starts. Neither one of these teams is very good at hitting the baseball, and with Martin being solid for Chicago, I like the under here. 

David Racey's Free Pick: Under 8.5

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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