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76ers vs Pacers Prediction 12/12/25 NBA Picks Today

Indiana Pacers (6-18) vs. Philadelphia 76ers (13-10)
December 12, 2025 7:00 pm EDT
The Line: Philadelphia 76ers -6.5; Over/Under: 230.5
(Get latest betting odds)

The Indiana Pacers and Philadelphia 76ers meet Friday in NBA action at the Xfinity Mobile Arena. Here’s a 76ers vs Pacers Prediction. This article will include a 76ers vs Pacers Pick.

Indiana Pacers Betting Preview

The Indiana Pacers beat the Bulls and Kings, and they play the Wizards next. The Pacers have lost 18 of their last 24 games.


The Indiana Pacers are averaging 111.3 points on 43.4 percent shooting and allowing 118.8 points on 47.7 percent shooting. Pascal Siakam is averaging 24.5 points and 7 rebounds, while Bennedict Mathurin is averaging 21.5 points and 5.6 rebounds. Andrew Nembhard is the third double-digit scorer, and Aaron Nesmith is grabbing 4.5 rebounds. The Indiana Pacers are shooting 33.2 percent from beyond the arc and 77.5 percent from the free-throw line. The Indiana Pacers are allowing 33.4 percent shooting from deep and are grabbing 44 rebounds per game.

Philadelphia 76ers Betting Preview

The Philadelphia 76ers beat the Bucks, lost to the Lakers, and they play the Hawks next. The 76ers have split their last 10 games.

The Philadelphia 76ers are averaging 116.9 points on 45.6 percent shooting and allowing 116.1 points on 46.4 percent shooting. Tyrese Maxey is averaging 31.5 points and 7.2 assists, while Joel Embiid is averaging 18.2 points and 5.6 rebounds. Kelly Oubre Jr. is the third double-digit scorer and Quentin Grimes is grabbing 4 rebounds. The Philadelphia 76ers are shooting 36.2 percent from beyond the arc and 81.5 percent from the free-throw line. The Philadelphia 76ers are allowing 34.3 percent shooting from deep and are grabbing 45 rebounds per game.

Why the Philadelphia 76ers will win

  • The Pacers have lost each of their last 10 games against teams that held a winning record.
  • The 76ers have won each of their last nine games as favorites when playing with a rest advantage.
  • The 76ers have covered the spread in each of their last eight games against Eastern Conference opponents that held a losing record.
  • The Pacers have failed to cover the spread in six of their last eight road games against teams that held a winning record.

Why the Indiana Pacers will win

  • The Pacers have won each of their last three games as underdogs against the 76ers.
  • The 76ers have lost each of their last three games as home favorites against Central Division opponents.
  • The road team has covered the spread in 10 of the 76ers’ last 11 games.
  • The 76ers have failed to cover the spread in 16 of their last 18 games as home favorites.

Total Points Facts

  • Ten of the Pacers’ last 11 games as road underdogs have gone UNDER the total points line.
  • Each of the 76ers’ last four games have gone UNDER the total points line.

Philadelphia 76ers Player Facts

  • VJ Edgecombe ranks 2nd amongst qualified rookies for assists per game (4.0) this season.
  • Quentin Grimes ranks T11th in the Eastern Conference amongst qualified players for FT% (85.7%) this season.

Indiana Pacers Player Facts

  • Jay Huff ranks 1st amongst qualified players for blocks per 36 minutes (4.7) this season.
  • Pascal Siakam is one of only five qualified players in the league to be leading their team in points (24.5), rebounds (7.0) and assists (4.1) per game this season.

Matchup/League Facts

  • The 76ers rank 1st in the league for blocks per game this season (6.1).
  • The 76ers have suffered the equal-largest comeback loss from a HT lead this season – led by 19 points vs Bulls on November 4.
  • The Pacers rank 30th in the league for assists per game this season (23.5).
  • The Pacers rank 30th in the league for field goal percentage this season (43.4%).

76ers vs Pacers Injury Report

The 76ers will be without Kelly Oubre Jr. and Trendon Watford.

The Pacers will be without Tyrese Haliburton, Obi Toppin, Kam Jones, Aaron Nesmith, and Ben Sheppard.

76ers vs Pacers Prediction

Don’t look now, but the Pacers have won 4 of their last 6 games and have covered 8 of their last 10 games. However, these wins came against the Kings, Bulls and Wizards, teams you, three of your friends, and myself could beat. The Pacers are still extremely banged up and not a team I trust night to night.

This is probably the healthiest the 76ers will be all season, as Embiid and Maxey are probable, while PG13 isn’t on the injury report at all. At home and with the stars together, this should be a good performance from the 76ers and the fans should be out in full force. While the 76ers are known to disappoint, so nothing would surprise me, this is a favorable spot and the line isn’t crazy. I’ll lay the points.

Randy Chambers's Free Pick: Philadelphia 76ers -6.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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