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Cavaliers vs Grizzlies Prediction 11/15/25 NBA Picks Today

Memphis Grizzlies (4-9) vs. Cleveland Cavaliers (8-5)
November 15, 2025 5:00 pm EDT
The Line: Cleveland Cavaliers -10.5; Over/Under: 238.5
(Get latest betting odds)

The Memphis Grizzlies and Cleveland Cavaliers meet Saturday in NBA action at the Rocket Arena. Here’s a Cavaliers vs Grizzlies Prediction. This article will include a Cavaliers vs Grizzlies Pick.

Memphis Grizzlies Betting Preview

The Memphis Grizzlies lost to the Celtics and Knicks, and they play the Spurs next. The Grizzlies have lost 7 of their last 8 games.

The Memphis Grizzlies are averaging 112.8 points on 43.5 percent shooting and allowing 120.7 points on 48.5 percent shooting. Ja Morant is averaging 18.9 points and 3.7 rebounds, while Jaren Jackson Jr. is averaging 17.2 points and 1.3 assists. Cedric Coward is the third double-digit scorer, and Santi Aldama is grabbing 6.5 rebounds. The Memphis Grizzlies are shooting 33.2 percent from beyond the arc and 83.2 percent from the free-throw line. The Memphis Grizzlies are allowing 36.6 percent shooting from deep and are grabbing 43.5 rebounds per game.

Cleveland Cavaliers Betting Preview

The Cleveland Cavaliers lost to the Raptors, beat the Heat, and they play the Bucks next. The Cavs have won 8 of their last 12 games.

The Cleveland Cavaliers are averaging 132.3 points on 45.3 percent shooting and allowing 128.1 points on 47.3 percent shooting. Donovan Mitchell is averaging 30.5 points and 5.5 assists, while Evan Mobley is averaging 19 points and 4.2 assists. De’Andre Hunter is the third double-digit scorer and Jarrett Allen is grabbing 7.9 rebounds. The Cleveland Cavaliers are shooting 34.8 percent from beyond the arc and 77.2 percent from the free throw line. The Cleveland Cavaliers are allowing 37.7 percent shooting from deep and are grabbing 47 rebounds per game.

Why the Cleveland Cavaliers will win

  • The Grizzlies have lost each of their last 11 night games against teams that held a winning record.
  • The Cavaliers have won each of their last nine home games against Southwest Division opponents that held a losing record.
  • The Grizzlies have failed to cover the spread in each of their last seven road games.
  • The favorites have covered the spread in 10 of the Grizzlies’ last 11 games.

Why the Memphis Grizzlies will win

  • The Grizzlies have won each of their last six games when playing with a rest advantage.
  • The Cavaliers have lost three of their last four games as home favorites following a loss.
  • The Cavaliers have failed to cover the spread in nine of their last 10 games at Rocket Arena.
  • The road team has covered the spread in five of the Cavaliers’ last six games.

Total Points Facts

  • Seven of the Cavaliers’ last eight home games against Western Conference opponents have gone OVER the total points line.
  • Five of the Grizzlies’ last six road games against Eastern Conference opponents have gone UNDER the total points line.

Cleveland Cavaliers Player Facts

  • Dean Wade ranks 4th amongst qualified players for assist:turnover ratio (5.0) this season.
  • Evan Mobley rank 8th amongst qualified players for steals + blocks per game (2.8) this season.

Memphis Grizzlies Player Facts

  • Jock Landale ranks 2nd amongst qualified Centers for 3P% (48.5%) this season.
  • Kentavious Caldwell-Pope ranks T25th amongst qualified players for FT% (88.5%) this season.

Matchup/League Facts

  • The Cavaliers rank 1st in the league for H2 points per game this season (62.2).
  • The Cavaliers rank T1st in the league for Q3 win percentage this season (76.9%).
  • The Grizzlies rank 4th in the league for opponent free throw attempts per game this season (22.8).
  • The Grizzlies rank 27th in the league for field goals made per game this season (38.9).

Cavaliers vs Grizzlies Injury Report

The Cavs will be without Max Strus, Jaylon Tyson, and Darius Garland.

The Grizzlies will be without Ty Jerome, Javon Small, Scotty Pippen Jr., Brandon Clarke, and Zach Edey. Olivier-Maxence Prosper is questionable.

Cavaliers vs Grizzlies Prediction

The Cavs are winning, but they’re just 4-9 ATS on the season, so I’m not thrilled to lay double-digit chalk. However, the Grizzlies aren’t winning and aren’t covering, as they’re 3-10 ATS on the season. The Grizzlies are in rough shape and the Morant trade rumors are still floating out there, which can’t be great for the locker room. Weird start time, which doesn’t help and usually leads to a sloppy, ugly game. I’m still going to lay the points with the Cavs, but it feels like a fade of the Grizzlies more than anything.

Randy Chambers's Free Pick: Cleveland Cavaliers -10.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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